James P. McDonald Week 12

From OpenWetWare

(Difference between revisions)
Jump to: navigation, search
(answered the first 4 questions)
(answered questions 5 and 6)
Line 8: Line 8:
#'''''What is the p value for the enrichment of genes in this profile?'''''
#'''''What is the p value for the enrichment of genes in this profile?'''''
#*p-value = 4.2E-4 (significant)
#*p-value = 4.2E-4 (significant)
-
 
+
#'''''How many GO terms are associated with this profile at p < 0.05?'''''
 +
#*11 of 112
 +
#'''''How many GO terms are associated with this profile with a corrected p value < 0.05?'''''
 +
#*0 of 112
 +
#'''''Look up the definitions for each of the terms at http://geneontology.org. Write a paragraph that describes the biological interpretation of these GO terms. In other words, why does the cell react to cold shock by changing the expression of genes associated with these GO terms?'''''
 +
#*
{{James P. McDonald}}
{{James P. McDonald}}
[[Category:BIOL398-03/S13]]
[[Category:BIOL398-03/S13]]

Revision as of 17:10, 11 April 2013

STEM

  1. Why did you select this profile? In other words, why was it interesting to you?
    • I chose profile 48. I did this because all the genes are consistently upregulated for the first 3 time points (t15, t30, t60) and then drop down around zero by t120. The genes appear to be responding similarly to the cold shock, suggesting consistent responses.
  2. How many genes belong to this profile?
    • 48 genes belong to this profile
  3. How many genes were expected to belong to this profile?
    • 28.4 genes were expected to belong to this profile
  4. What is the p value for the enrichment of genes in this profile?
    • p-value = 4.2E-4 (significant)
  5. How many GO terms are associated with this profile at p < 0.05?
    • 11 of 112
  6. How many GO terms are associated with this profile with a corrected p value < 0.05?
    • 0 of 112
  7. Look up the definitions for each of the terms at http://geneontology.org. Write a paragraph that describes the biological interpretation of these GO terms. In other words, why does the cell react to cold shock by changing the expression of genes associated with these GO terms?

Class Links

Journal Entries and Assignments

Personal tools