Jane Johnson Lab:Projects: Difference between revisions
From OpenWetWare
Jump to navigationJump to search
Helen C. Lai (talk | contribs) mNo edit summary |
Helen C. Lai (talk | contribs) mNo edit summary |
||
| Line 3: | Line 3: | ||
<br style="clear:both" /> | <br style="clear:both" /> | ||
<div style="padding: 10px; width: 753px; border: 5px solid #CCCCFF;"> | <div style="padding: 10px; width: 753px; border: 5px solid #CCCCFF;"> | ||
We are investigating the role of basic helix-loop-helix (bHLH)transcription factors in differentiation and cell-type specification of neural subtypes. We are determining the cis-regulatory code and downstream targets of Atoh1, Neurog1/2, Ascl1, and Ptf1a. In addition, we are tracing the lineage of these factors to assess the ultimate cell fate of the neural subtypes they specify. | |||
[[Image:JaneJohnsonLabMath1.jpg|thumb|LacZ expression in the Atoh1 domains]]<br> | |||
[[Image:Nakada.png|thumb|GFP expression in the Neurog1 domains]]<br> | [[Image:Nakada.png|thumb|GFP expression in the Neurog1 domains]]<br> | ||
[[Image:Battiste.png|thumb|LacZ expression in the Ascl1 domains]]<br> | [[Image:Battiste.png|thumb|LacZ expression in the Ascl1 domains]]<br> | ||
[[Image:Glasgow.png|thumb|LacZ expression in the Ptf1a domains]]<br> | [[Image:Glasgow.png|thumb|LacZ expression in the Ptf1a domains]]<br> | ||
Page is in progress... | Page is in progress... | ||
Revision as of 10:45, 9 February 2009
|
We are investigating the role of basic helix-loop-helix (bHLH)transcription factors in differentiation and cell-type specification of neural subtypes. We are determining the cis-regulatory code and downstream targets of Atoh1, Neurog1/2, Ascl1, and Ptf1a. In addition, we are tracing the lineage of these factors to assess the ultimate cell fate of the neural subtypes they specify.
Page is in progress...
