Jane Johnson Lab:Projects: Difference between revisions
From OpenWetWare
Jump to navigationJump to search
Helen C. Lai (talk | contribs) mNo edit summary |
Helen C. Lai (talk | contribs) mNo edit summary |
||
Line 4: | Line 4: | ||
<div style="padding: 10px; width: 753px; border: 5px solid #CCCCFF;"> | <div style="padding: 10px; width: 753px; border: 5px solid #CCCCFF;"> | ||
We are investigating the role of basic helix-loop-helix (bHLH)transcription factors in differentiation and cell-type specification of neural subtypes. We are determining the cis-regulatory code and downstream targets of Atoh1, Neurog1/2, Ascl1, and Ptf1a. In addition, we are tracing the lineage of these factors to assess the ultimate cell fate of the neural subtypes they specify. | We are investigating the role of basic helix-loop-helix (bHLH)transcription factors in differentiation and cell-type specification of neural subtypes. We are determining the cis-regulatory code and downstream targets of Atoh1, Neurog1/2, Ascl1, and Ptf1a. In addition, we are tracing the lineage of these factors to assess the ultimate cell fate of the neural subtypes they specify.<br> | ||
Page is in progress... | |||
<gallery> | <gallery> | ||
Line 12: | Line 14: | ||
Image:Glasgow.png|LacZ expression in the Ptf1a domains | Image:Glasgow.png|LacZ expression in the Ptf1a domains | ||
<gallery> | <gallery> | ||
Revision as of 10:49, 9 February 2009
|
We are investigating the role of basic helix-loop-helix (bHLH)transcription factors in differentiation and cell-type specification of neural subtypes. We are determining the cis-regulatory code and downstream targets of Atoh1, Neurog1/2, Ascl1, and Ptf1a. In addition, we are tracing the lineage of these factors to assess the ultimate cell fate of the neural subtypes they specify.
Page is in progress...
<gallery> Image:JaneJohnsonLabMath1.jpg|LacZ expression in the Atoh1 domains Image:Nakada.png|GFP expression in the Neurog1 domains Image:Battiste.png|LacZ expression in the Ascl1 domains Image:Glasgow.png|LacZ expression in the Ptf1a domains <gallery>