Janelle N. Ruiz Assignment 7

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Vocabulary

  1. Glycoprotein: A molecule that consists of a carbohydrate plus a protein. Glycoproteins play essential roles in the body. For instance, in the immune system almost all of the key molecules involved in the immune response are glycoproteins. http://www.medterms.com/script/main/art.asp?articlekey=16842
  2. Oligomer: A molecule that consists of a relatively small and specifiable number of monomers (usually less than five). Unlike a polymer, if one of the monomers is removed from an oligomer, its chemical properties are altered. http://www.thefreedictionary.com/oligomeric
  3. Discontinuous: Meaning that more than one segment of the polypeptide is required to form the domain. This is likely to be the result of the insertion of one domain into another during the protein's evolution. It has been shown from known structures that about a quarter of structural domains are discontinuous. http://en.wikipedia.org/wiki/Protein_domain
  4. Ectodomain: the part of a membrane protein that extends into the extracellular space (the space outside a cell). Ectodomains are usually the part of a protein that initiate contact with surface which leads to signal transduction. en.wikipedia.org/wiki/Ectodomain
  5. Glycosylation: Proteins are modified by the addition of carbohydrates (glycosylation) to specific amino acids in the peptide chain. www.encyclopedia.com/doc/1G2-3400700147.html
  6. Immunogenicity: the ability of a particular substance, such as an antigen or epitope, to provoke an immune response. en.wikipedia.org/wiki/Immunogenicity
  7. Antigenicity: the ability of a chemical structure (refered to as an Antigen) to bind specifically with certain products of adaptive immunity: T cell receptors or Antibodies (a.k.a. B cell receptors). en.wikipedia.org/wiki/Antigenicity
  8. Chemokine: a small protein molecule that activates immune cells, stimulates their migration, and helps direct immune cell traffic throughout the body. www3.niaid.nih.gov/topics/immuneSystem/glossary.htm
  9. Fusogenic: Facilitating fusion of the viral envelope with the cellular plasma membrane. www.nature.com/nrg/journal/v4/n5/glossary/nrg1066_glossary.html
  10. Prophylactic: A medical procedure or practice that prevents or protects against a disease or condition (eg, vaccines, antibiotics, drugs). www.pandemicflu.gov/glossary/
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