Javidlab

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Current revision (04:16, 18 February 2014) (view source)
 
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[[Javidlab | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Home''' </font>]] &nbsp;&nbsp;&nbsp;
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[[Javidlab | <font face="trebuchet ms" size=4 style="color:#ffffff"> '''Home ''' </font>]]
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[[Javidlab:research | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Research''' </font>]] &nbsp;&nbsp;&nbsp;
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[[Javidlab:news | <font face="trebuchet ms" size=4 style="color:#ffffff"> '''/  NEWS  ''' </font>]]
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[[Javidlab:publications | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Publications''' </font>]] &nbsp;&nbsp;&nbsp;
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[[Javidlab:research | <font face="trebuchet ms" size=4 style="color:#ffffff"> '''Research ''' </font>]]
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[[Javidlab:labmembers | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Lab Members''' </font>]] &nbsp;&nbsp;&nbsp;
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[[Javidlab:publications | <font face="trebuchet ms" size=4 style="color:#ffffff"> '''Publications ''' </font>]]
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[[Javidlab:labalumni | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Lab Alumni''' </font>]] &nbsp;&nbsp;&nbsp;
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[[Javidlab:labmembers | <font face="trebuchet ms" size=4 style="color:#ffffff"> '''Lab Members ''' </font>]]
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[[Javidlab:funstuff | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Fun Stuff''' </font>]]&nbsp;&nbsp;&nbsp;
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[[Javidlab:labalumni | <font face="trebuchet ms" size=4 style="color:#ffffff"> '''Lab Alumni ''' </font>]]
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[[Javidlab:contact | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Contact''' </font>]]
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[[Javidlab:funstuff | <font face="trebuchet ms" size=4 style="color:#ffffff"> '''Fun Stuff ''' </font>]]
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[[Javidlab:contact | <font face="trebuchet ms" size=4 style="color:#ffffff"> '''Contact /''' </font>]]
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By NIAID on Flickr. [http://www.flickr.com/photos/niaid/5149398678/], via Wikimedia Commons
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MAIN<br>
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TOPIC<br>
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1. 'Adaptive mistranslation'<br>
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2. Mycobacteria and host-pathogen interactions<br>
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3. Protein translation fidelity<br>
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4. GatCAB dependent tRNA synthesis and protein evolution<br>
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<br>
RESEARCH INTEREST<br>
RESEARCH INTEREST<br>
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The Javid lab principal interest is in mycobacterial pathophysiology. Tuberculosis causes more infectious disease deaths in China than any other pathogen, and the basic biology of its causative organism,Mycobacterium tuberculosis is still poorly understood.Our lab is interested in how fundamental physiological processes in mycobacteria can influence important clinical phenotypes such as antibiotic tolerance and immune evasion. We have shown that altering the protein translation error rate in mycobacteria can profoundly influence phenotypic resistance to first-line anti-mycobacterial drugs. We are now trying to understand the molecular mechanism and regulation of translational fidelity.Mycobacterium tuberculosis can reside within the host for decades without detection. We are trying to understand how this happens -- at the level of both innate and adaptive immunity.
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<br>
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The Javid lab principal interest is in mycobacterial pathophysiology. Here are some of research interests:<br><br>
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<font face="calibri" size="4">'''1. 'Adaptive mistranslation''''</font><br>
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<font face="calibri" size="4">'''2. Mycobacteria and host-pathogen interactions'''</font><br>
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<font face="calibri" size="4">'''3. Protein translation fidelity'''</font><br>
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<font face="calibri" size="4">'''4. GatCAB dependent tRNA synthesis and protein evolution'''</font><br><br>
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Undergraduate and graduate students, as well as post-doctoral scientists, interested in our work should contact Dr. Javid directly. (email: ''bjavid{at}gmail.com'')
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== >>>>>>>>>>><br> <font face="trebuchet ms" size=2 style="color:#930000"> '''See our members in the LINK below''' </font> ==
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== >>>>>>>>>>><br> <font face="trebuchet ms" size=2 style="color:#CC0000"> '''Find who's NEW here!<br> via the LINK below''' </font> ==
LINK:<br>
LINK:<br>
[[Javidlab:labmembers]]
[[Javidlab:labmembers]]
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== <font face="trebuchet ms" size=2 style="color:#930000"> '''Amaze yourself by seeing the LINK below''' </font> ==
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== <font face="trebuchet ms" size=2 style="color:#CC0000"> '''Amaze yourself<br> via the LINK below''' </font> ==
LINK:<br>
LINK:<br>
[[Javidlab:research]]
[[Javidlab:research]]
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Lab name written by Nano Luciferase
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‘STOP TB’ written<br> by Nano Luciferase<br>
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(flashing by computer programming)<br>
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== <<<<<<<<<<<<br> <font face="trebuchet ms" size=4 style="color:#930000"> '''Nano Luciferase''' </font> ==
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== <<<<<<<<<<<<br> <font face="trebuchet ms" size=4 style="color:#CC0000"> '''Nano Luciferase''' </font> ==
Bio_luminescence by Nano Luciferase (Promega), which we optimised to be easily expressed in Mycobacterium, and a novel mistranslation reporter with 100 times higher signal over canonical Renilla luciferase.
Bio_luminescence by Nano Luciferase (Promega), which we optimised to be easily expressed in Mycobacterium, and a novel mistranslation reporter with 100 times higher signal over canonical Renilla luciferase.
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Room 4-302 Biotech Building<br>
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School of Medicine<br>
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Tsinghua University
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Current revision




RESEARCH INTEREST



The Javid lab principal interest is in mycobacterial pathophysiology. Here are some of research interests:

1. 'Adaptive mistranslation'
2. Mycobacteria and host-pathogen interactions
3. Protein translation fidelity
4. GatCAB dependent tRNA synthesis and protein evolution

Undergraduate and graduate students, as well as post-doctoral scientists, interested in our work should contact Dr. Javid directly. (email: bjavid{at}gmail.com)

>>>>>>>>>>>
Find who's NEW here!
via the LINK below

LINK:
Javidlab:labmembers


Amaze yourself
via the LINK below

LINK:
Javidlab:research




‘STOP TB’ written
by Nano Luciferase
(flashing by computer programming)

<<<<<<<<<<<
Nano Luciferase

Bio_luminescence by Nano Luciferase (Promega), which we optimised to be easily expressed in Mycobacterium, and a novel mistranslation reporter with 100 times higher signal over canonical Renilla luciferase.


Room 4-302 Biotech Building
School of Medicine
Tsinghua University

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