Javidlab

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'''Room 4-304 Biotech Building'''<br>
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[[Javidlab | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Home''' </font>]] &nbsp;&nbsp;&nbsp;
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'''School of Medicine, Tsinghua University'''<br>
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[[Javidlab:research | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Research''' </font>]] &nbsp;&nbsp;&nbsp;
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[[Javidlab:publications | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Publications''' </font>]] &nbsp;&nbsp;&nbsp;
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[[Javidlab:labmembers | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Lab Members''' </font>]] &nbsp;&nbsp;&nbsp;
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[[Javidlab:labalumni | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Lab Alumni''' </font>]] &nbsp;&nbsp;&nbsp;
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[[Javidlab:funstuff | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Fun Stuff''' </font>]]&nbsp;&nbsp;&nbsp;
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[[Javidlab:contact | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''Contact''' </font>]]
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[[Javidlab | <font face="trebuchet ms" size=2 style="color:#ffffff"> '''HOME''' </font>]]
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By NIAID on Flickr. [http://www.flickr.com/photos/niaid/5149398678/], via Wikimedia Commons
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[[Javidlab:news | <font face="trebuchet ms" size=2 style="color:#ffffff"> '''NEWS''' </font>]]
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[[Javidlab:research | <font face="trebuchet ms" size=2 style="color:#ffffff"> '''Research''' </font>]]
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[[Javidlab:publications | <font face="trebuchet ms" size=2 style="color:#ffffff"> '''Publication''' </font>]]
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[[Javidlab:labmembers | <font face="trebuchet ms" size=2 style="color:#ffffff"> '''Members''' </font>]]
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[[Javidlab:labalumni | <font face="trebuchet ms" size=2 style="color:#ffffff"> '''Alumni''' </font>]]
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[[Javidlab:funstuff | <font face="trebuchet ms" size=2 style="color:#ffffff"> '''Fun''' </font>]]
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[[Javidlab:contact | <font face="trebuchet ms" size=2 style="color:#ffffff"> '''Contact''' </font>]]
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MAIN<br>
 
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TOPIC<br>
 
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1. 'Adaptive mistranslation'<br>
 
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2. Mycobacteria and host-pathogen interactions<br>
 
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3. Protein translation fidelity<br>
 
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4. GatCAB dependent tRNA synthesis and protein evolution<br>
 
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<font face="trebuchet ms" size=6 style="color:#000079"><br>RESEARCH INTEREST<br></font>
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The Javid lab principal interest is in mycobacterial pathophysiology. Here are some of research interests:<br><br>
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<font face="calibri" size="4">'''1. 'Adaptive mistranslation''''</font><br>
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<font face="calibri" size="4">'''2. Mycobacteria and host-pathogen interactions'''</font><br>
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<font face="calibri" size="4">'''3. Protein translation fidelity'''</font><br>
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<font face="calibri" size="4">'''4. GatCAB dependent tRNA synthesis and protein evolution'''</font><br><br>
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<font style="color:#000079"> Undergraduate and graduate students, as well as post-doctoral scientists, interested in our work should contact Dr. Javid directly.  (email: ''bjavid{at}gmail.com'') </font>
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RESEARCH INTEREST<br>
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----
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The Javid lab principal interest is in mycobacterial pathophysiology. Tuberculosis causes more infectious disease deaths in China than any other pathogen, and the basic biology of its causative organism,Mycobacterium tuberculosis is still poorly understood.Our lab is interested in how fundamental physiological processes in mycobacteria can influence important clinical phenotypes such as antibiotic tolerance and immune evasion. We have shown that altering the protein translation error rate in mycobacteria can profoundly influence phenotypic resistance to first-line anti-mycobacterial drugs. We are now trying to understand the molecular mechanism and regulation of translational fidelity.Mycobacterium tuberculosis can reside within the host for decades without detection. We are trying to understand how this happens -- at the level of both innate and adaptive immunity.
 
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== >>>>>>>>>>><br> <font face="trebuchet ms" size=2 style="color:#930000"> '''See our members in the LINK below''' </font> ==
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LINK:<br>
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[[Javidlab:labmembers]]
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== <font face="trebuchet ms" size=2 style="color:#930000"> '''Amaze yourself by seeing the LINK below''' </font> ==
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LINK:<br>
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[[Javidlab:research]]
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''Exciting things happen here''
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''I love my research in Javid Lab''
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''Meet our lovely members''
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Lab name written by Nano Luciferase
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''Happy Hours''
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== <<<<<<<<<<<<br> <font face="trebuchet ms" size=4 style="color:#930000"> '''Nano Luciferase''' </font> ==
 
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Bio_luminescence by Nano Luciferase (Promega), which we optimised to be easily expressed in Mycobacterium, and a novel mistranslation reporter with 100 times higher signal over canonical Renilla luciferase.
 
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Current revision



Room 4-304 Biotech Building
School of Medicine, Tsinghua University

HOME

NEWS

Research

Publication

Members

Alumni

Fun

Contact


RESEARCH INTEREST

The Javid lab principal interest is in mycobacterial pathophysiology. Here are some of research interests:

1. 'Adaptive mistranslation'
2. Mycobacteria and host-pathogen interactions
3. Protein translation fidelity
4. GatCAB dependent tRNA synthesis and protein evolution

Undergraduate and graduate students, as well as post-doctoral scientists, interested in our work should contact Dr. Javid directly. (email: bjavid{at}gmail.com)


Exciting things happen here

I love my research in Javid Lab

Meet our lovely members

Happy Hours


Personal tools