Javidlab: Difference between revisions
Babak Javid (talk | contribs) No edit summary |
Babak Javid (talk | contribs) No edit summary |
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1. 'Adaptive mistranslation'<br> | 1. 'Adaptive mistranslation'<br> | ||
2. Mycobacteria and host-pathogen interactions<br> | 2. Mycobacteria and host-pathogen interactions<br> | ||
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RESEARCH | RESEARCH INTEREST<br> | ||
INTEREST<br> | |||
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The Javid lab principal interest is in mycobacterial pathophysiology. Tuberculosis causes more infectious disease deaths in China than any other pathogen, and the basic biology of its causative organism,Mycobacterium tuberculosis is still poorly understood.Our lab is interested in how fundamental physiological processes in mycobacteria can influence important clinical phenotypes such as antibiotic tolerance and immune evasion. We have shown that altering the protein translation error rate in mycobacteria can profoundly influence phenotypic resistance to first-line anti-mycobacterial drugs. We are now trying to understand the molecular mechanism and regulation of translational fidelity.Mycobacterium tuberculosis can reside within the host for decades without detection. We are trying to understand how this happens -- at the level of both innate and adaptive immunity. | The Javid lab principal interest is in mycobacterial pathophysiology. Tuberculosis causes more infectious disease deaths in China than any other pathogen, and the basic biology of its causative organism,Mycobacterium tuberculosis is still poorly understood.Our lab is interested in how fundamental physiological processes in mycobacteria can influence important clinical phenotypes such as antibiotic tolerance and immune evasion. We have shown that altering the protein translation error rate in mycobacteria can profoundly influence phenotypic resistance to first-line anti-mycobacterial drugs. We are now trying to understand the molecular mechanism and regulation of translational fidelity.Mycobacterium tuberculosis can reside within the host for decades without detection. We are trying to understand how this happens -- at the level of both innate and adaptive immunity. | ||
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== >>>>>>>>>>><br> <font face="trebuchet ms" size= | == >>>>>>>>>>><br> <font face="trebuchet ms" size=2 style="color:#930000"> '''See our members in the LINK below''' </font> == | ||
LINK:<br> | LINK:<br> | ||
[[Javidlab:labmembers]] | [[Javidlab:labmembers]] | ||
<br> | <br> | ||
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== <font face="trebuchet ms" size=2 style="color:#930000"> '''Amaze yourself by seeing the LINK below''' </font> == | |||
LINK:<br> | LINK:<br> | ||
[[Javidlab:research]] | [[Javidlab:research]] | ||
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Revision as of 04:58, 23 May 2013
RESEARCH INTEREST The Javid lab principal interest is in mycobacterial pathophysiology. Tuberculosis causes more infectious disease deaths in China than any other pathogen, and the basic biology of its causative organism,Mycobacterium tuberculosis is still poorly understood.Our lab is interested in how fundamental physiological processes in mycobacteria can influence important clinical phenotypes such as antibiotic tolerance and immune evasion. We have shown that altering the protein translation error rate in mycobacteria can profoundly influence phenotypic resistance to first-line anti-mycobacterial drugs. We are now trying to understand the molecular mechanism and regulation of translational fidelity.Mycobacterium tuberculosis can reside within the host for decades without detection. We are trying to understand how this happens -- at the level of both innate and adaptive immunity.
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