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Molecular and Systems Biotechnology Lab @ UIUC

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Kew words 2017 Lee, Y. G., Jin, Y. S., Cha, Y. L. & Seo, J. H. (2017). Bioethanol production from cellulosic hydrolysates by engineered industrial Saccharomyces cerevisiae. Bioresource Technology, 228, 355-361. Kwak, S., & Jin, Y. S. (2017). Production of fuels and chemicals from xylose by engineered Saccharomyces cerevisiae: a review and perspective. Microbial cell factories, 16(1), 82. Kim, S. R., Skerker, J. M., Kong, I. I., Kim, H., Maurer, M. J., Zhang, G. C., ... & Jin, Y. S. (2017). Metabolic engineering of a haploid strain derived from a triploid industrial yeast for producing cellulosic ethanol. Metabolic Engineering, 40, 176-185. Lee, W. H., & Jin, Y. S. (2017). Improved ethanol production by engineered Saccharomyces cerevisiae expressing a mutated cellobiose transporter during simultaneous saccharification and fermentation. Journal of Biotechnology, 245, 1-8. Turner, T. L., Kim, E., Hwang, C., Zhang, G. C., Liu, J. J., & Jin, Y. S. (2017). Short communication: Conversion of lactose and whey into lactic acid by engineered yeast. Journal of Dairy Science, 100(1), 124-128. Zhang, G. C., Turner, T. L., & Jin, Y. S. (2017). Enhanced xylose fermentation by engineered yeast expressing NADH oxidase through high cell density inoculums. Journal of Industrial Microbiology & Biotechnology, 1-9. Seo, S. O., Wang, Y., Lu, T., Jin, Y. S., & Blaschek, H. P. (2017). Characterization of a Clostridium beijerinckii spo0A mutant and its application for butyl butyrate production. Biotechnology and Bioengineering, 114(1), 106-112. 2016 Zhang, G. C., Kong, I. I., Wei, N., Peng, D., Turner, T. L., Sung, B. H., ... & Jin, Y. S. (2016). Optimization of an acetate reduction pathway for producing cellulosic ethanol by engineered yeast. Biotechnology and Bioengineering, 113(12), 2587-2596. Xia, P. F., Zhang, G. C., Walker, B., Seo, S. O., Kwak, S., Liu, J. J., ... & Jin, Y. S. (2016). Recycling Carbon Dioxide during Xylose Fermentation by Engineered Saccharomyces cerevisiae. ACS Synthetic Biology. Xia, P. F., Zhang, G. C., Liu, J. J., Kwak, S., Tsai, C. S., Kong, I. I., ... & Jin, Y. S. (2016). GroE chaperonins assisted functional expression of bacterial enzymes in Saccharomyces cerevisiae. Biotechnology and Bioengineering, 113(10), 2149-2155. Turner, T. L., Kim, H., Kong, I. I., Liu, J. J., Zhang, G. C., & Jin, Y. S. (2016). Engineering and Evolution of Saccharomyces cerevisiae to Produce Biofuels and Chemicals. (Book Chapter) Kim, J. W., Kim, J., Seo, S. O., Kim, K. H., Jin, Y. S., & Seo, J. H. (2016). Enhanced production of 2, 3-butanediol by engineered Saccharomyces cerevisiae through fine-tuning of pyruvate decarboxylase and NADH oxidase activities. Biotechnology for Biofuels, 9(1), 265. Park, J., Wang, Z., Lee, W.-H., Jameel, H., Jin, Y.-S., and Park, S. (2016) Effect of the two-stage autohydrolysis of hardwood on the enzymatic saccharification and subsequent fermentation with an efficient xylose-utilizing Saccharomyces cerevisiae. BioResources 11, 9584-9595 Choi, E. J., Kim, J. W., Kim, S. J., Seo, S. O., Lane, S., Park, Y. C., ... & Seo, J. H. (2016). Enhanced production of 2, 3‐butanediol in pyruvate decarboxylase‐deficient Saccharomyces cerevisiae through optimizing ratio of glucose/galactose. Biotechnology Journal, 11(11), 1424-1432. Liu, J. J., Zhang, G. C., Oh, E. J., Pathanibul, P., Turner, T. L., and Jin, Y. S. (2016) Lactose fermentation by engineered Saccharomyces cerevisiae capable of fermenting cellobiose. Journal of Biotechnology 234, 99-104 Wang, Y., Zhang, Z. T., Seo, S. O., Lynn, P., Lu, T., Jin, Y. S., & Blaschek, H. P. (2016). Gene transcription repression in Clostridium beijerinckii using CRISPR‐dCas9. Biotechnology and Bioengineering, 113(12), 2739-2743. Quarterman, J., Skerker, J. M., Feng, X., Liu, I. Y., Zhao, H., Arkin, A. P., and Jin, Y. S. (2016) Rapid and efficient galactose fermentation by engineered Saccharomyces cerevisiae. Journal of Biotechnology 229, 13-21 Wang, Y., Zhang, Z. T., Seo, S. O., Lynn, P., Lu, T., Jin, Y. S., and Blaschek, H. P. (2016) Bacterial genome editing with CRISPR-Cas9: deletion, integration, single nucleotide modification, and desirable "clean" mutant selection in Clostridium beijerinckii as an example. ACS Synthetic Biology 15, 721-732 Oh, E. J., Skerker, J. M., Kim, S. R., Wei, N., Turner, T. L., Maurer, M. J., Arkin, A. P., and Jin, Y. S. (2016) Gene amplification on demand accelerates cellobiose utilization in engineered Saccharomyces cerevisiae. Applied and Environmental Microbiology 82, 3631-3639 Xu, H., Kim, S., Sorek, H., Lee, Y., Jeong, D., Kim, J., Oh, E. J., Yun, E. J., Wemmer, D. E., Kim, K. H., Kim, S. R., and Jin, Y. S. (2016) PHO13 deletion-induced transcriptional activation prevents sedoheptulose accumulation during xylose metabolism in engineered Saccharomyces cerevisiae. Metabolic Engineering 34, 88-96 Xia, P. F., Zhang, G. C., Liu, J. J., Kwak, S., Tsai, C. S., Kong, II, Sung, B. H., Sohn, J. H., Wang, S. G., and Jin, Y. S. (2016) GroE chaperonins assisted functional expression of bacterial enzymes in Saccharomyces cerevisiae. Biotechnology and Bioengineering 113, 2149-2155 Seo, J. H., and Jin, Y. S. (2016) Editorial overview: Food biotechnology: Critical gap filler in the nexus of food, energy, and waste for a prosperous future. Current Opinion in Biotechnology 37, 4-7 Park, Y. C., Oh, E. J., Jo, J. H., Jin, Y. S., and Seo, J. H. (2016) Recent advances in biological production of sugar alcohols. Current Opinion in Biotechnology 37, 105-113 Liu, J. J., Kong, II, Zhang, G. C., Jayakody, L. N., Kim, H., Xia, P. F., Kwak, S., Sung, B. H., Sohn, J. H., Walukiewicz, H. E., Rao, C. V., and Jin, Y. S. (2016) Metabolic engineering of probiotic Saccharomyces boulardii. Applied and Environmental Microbiology 82, 2280-2287 Li, X., Park, A., Estrela, R., Kim, S. R., Jin, Y. S., and Cate, J. H. D. (2016) Comparison of xylose fermentation by two high-performance engineered strains of Saccharomyces cerevisiae. Biotechnology Reports 9, 53-56 Kim, J. S., Cho, D. H., Heo, P., Jung, S. C., Park, M., Oh, E. J., Sung, J., Kim, P. J., Lee, S. C., Lee, D. H., Lee, S., Lee, C. H., Shin, D., Jin, Y. S., and Kweon, D. H. (2016) Fumarate-mediated persistence of Escherichia coli against antibiotics. Antimicrobial Agents and Chemotherapy 60, 2232-2240 Jayakody, L. N., Lane, S., Kim, H., and Jin, Y. S. (2016) Mitigating health risks associated with alcoholic beverages through metabolic engineering. Current Opinion in Biotechnology 37, 173-181 2015 Zhang, G. C., Liu, J. J., Kong, I. I., Kwak, S., and Jin, Y. S. (2015) Combining C6 and C5 sugar metabolism for enhancing microbial bioconversion. Current Opinion in Chemical Biology 29, 49-57 Yun, E. J., Kwak, S., Kim, S. R., Park, Y. C., Jin, Y. S., and Kim, K. H. (2015) Production of (S)-3-hydroxybutyrate by metabolically engineered Saccharomyces cerevisiae. Journal of Biotechnology 209, 23-30 Wei, N., Oh, E. J., Million, G., Cate, J. H. D., and Jin, Y. S. (2015) Simultaneous utilization of cellobiose, xylose, and acetic acid from lignocellulosic biomass for biofuel production by an engineered yeast platform. ACS Synthetic Biology 4, 707-713 Wang, Y., Zhang, Z. T., Seo, S. O., Choi, K., Lu, T., Jin, Y. S., and Blaschek, H. P. (2015) Markerless chromosomal gene deletion in Clostridium beijerinckii using CRISPR/Cas9 system. Journal of Biotechnology 200, 1-5 Turner, T. L., Zhang, G. C., Oh, E. J., Subramaniam, V., Adiputra, A., Subramaniam, V., Skory, C. D., Jang, J. Y., Yu, B. J., Park, I., and Jin, Y. S. (2015) Lactic acid production from cellobiose and xylose by engineered Saccharomyces cerevisiae. Biotechnology and Bioengineering 113, 1075-1083 Turner, T. L., Zhang, G. C., Kim, S. R., Subramaniam, V., Steffen, D., Skory, C. D., Jang, J. Y., Yu, B. J., and Jin, Y. S. (2015) Lactic acid production from xylose by engineered Saccharomyces cerevisiae without PDC or ADH deletion. Applied Microbiology and Biotechnology 99, 8023-8033 Tsai, C. S., Kwak, S., Turner, T. L., and Jin, Y. S. (2015) Yeast synthetic biology toolbox and applications for biofuel production. FEMS Yeast Research 15, 1-15 Tsai, C. S., Kong, I. I., Lesmana, A., Million, G., Zhang, G. C., Kim, S. R., and Jin, Y. S. (2015) Rapid and marker-free refactoring of xylose-fermenting yeast strains with Cas9/CRISPR. Biotechnology and Bioengineering 112, 2406-2411 Quarterman, J., Kim, S. R., Kim, P. J., and Jin, Y. S. (2015) Enhanced hexose fermentation by Saccharomyces cerevisiae through integration of stoichiometric modeling and genetic screening. Journal of Biotechnology 194, 48-57 Liao, C., Seo, S. O., Celik, V., Liu, H., Kong, W., Wang, Y., Blaschek, H., Jin, Y. S., and Lu, T. (2015) Integrated, systems metabolic picture of acetone-butanol-ethanol fermentation by Clostridium acetobutylicum. Proceedings of the National Academy of Sciences of the United States of America 112, 8505-8510 Li, X., Yu, V. Y., Lin, Y., Chomvong, K., Estrela, R., Park, A., Liang, J. M., Znameroski, E. A., Feehan, J., Kim, S. R., Jin, Y. S., Louise Glass, N., and Cate, J. H. D. (2015) Expanding xylose metabolism in yeast for plant cell wall conversion to biofuels. eLife 4, 1-55 Lewis, Z. T., Totten, S. M., Smilowitz, J. T., Popovic, M., Parker, E., Lemay, D. G., Van Tassell, M. L., Miller, M. J., Jin, Y. S., German, J. B., Lebrilla, C. B., and Mills, D. A. (2015) Maternal fucosyltransferase 2 status affects the gut bifidobacterial communities of breastfed infants. Microbiome 3, 13 Lane, S., Zhang, S., Wei, N., Rao, C., and Jin, Y. S. (2015) Development and physiological characterization of cellobiose-consuming Yarrowia lipolytica. Biotechnology and Bioengineering 112, 1012-1022 Kim, S. R., Xu, H., Lesmana, A., Kuzmanovic, U., Au, M., Florencia, C., Oh, E. J., Zhang, G., Kim, K. H., and Jin, Y. S. (2015) Deletion of PHO13, encoding haloacid dehalogenase type IIA phosphatase, results in upregulation of the pentose phosphate pathway in Saccharomyces cerevisiae. Applied and Environmental Microbiology 81, 1601-1609 Kim, S. M., Guo, J., Kwak, S., Jin, Y. S., Lee, D. K., and Singh, V. (2015) Effects of genetic variation and growing condition of prairie cordgrass on feedstock composition and ethanol yield. Bioresource Technology 183, 70-77 Kim, S. K., Jin, Y. S., Choi, I. G., Park, Y. C., and Seo, J. H. (2015) Enhanced tolerance of Saccharomyces cerevisiae to multiple lignocellulose-derived inhibitors through modulation of spermidine contents. Metabolic Engineering 29, 46-55 Kim, S., Sung, J., Foo, M., Jin, Y. S., and Kim, P. J. (2015) Uncovering the nutritional landscape of food. PLoS ONE 10 Kim, J. W., Seo, S. O., Zhang, G. C., Jin, Y. S., and Seo, J. H. (2015) Expression of Lactococcus lactis NADH oxidase increases 2,3-butanediol production in Pdc-deficient Saccharomyces cerevisiae. Bioresource Technology 191, 512-519 2014 Zhang, G. C., Kong, I. I., Kim, H., Liu, J. J., Cate, J. H. D., and Jin, Y. S. (2014) Construction of a quadruple auxotrophic mutant of an industrial polyploid Saccharomyces cerevisiae strain by using RNA-guided Cas9 nuclease. Applied and Environmental Microbiology 80, 7694-7701 Nan, H., Seo, S. O., Oh, E. J., Seo, J. H., Cate, J. H. D., and Jin, Y. S. (2014) 2,3-Butanediol production from cellobiose by engineered Saccharomyces cerevisiae. Applied Microbiology and Biotechnology 98, 5757-5764 Lin, Y., Chomvong, K., Acosta-Sampson, L., Estrela, R., Galazka, J. M., Kim, S. R., Jin, Y. S., and Cate, J. H. (2014) Leveraging transcription factors to speed cellobiose fermentation by Saccharomyces cerevisiae. Biotechnology for Biofuels 7 Kim, T. Y., Oh, E. J., Jin, Y. S., and Oh, M. K. (2014) Improved resistance against oxidative stress of engineered cellobiose-fermenting Saccharomyces cerevisiae revealed by metabolite profiling. Biotechnology and Bioprocess Engineering 19, 951-957 Kim, S. R., and Jin, Y. S. (2014) Metabolic engineering of Saccharomyces cerevisiae for redox balance of xylose fermentation. Current Research on Agriculture and Life Sciences 32, 199-202 Kim, S. J., Seo, S. O., Park, Y. C., Jin, Y. S., and Seo, J. H. (2014) Production of 2,3-butanediol from xylose by engineered Saccharomyces cerevisiae. Journal of Biotechnology 192, 376-382 Kim, H., Lee, W. H., Galazka, J. M., Cate, J. H. D., and Jin, Y. S. (2014) Analysis of cellodextrin transporters from Neurospora crassa in Saccharomyces cerevisiae for cellobiose fermentation. Applied Microbiology and Biotechnology 98, 1087-1094 Chomvong, K., Kordić, V., Li, X., Bauer, S., Gillespie, A. E., Ha, S. J., Oh, E. J., Galazka, J. M., Jin, Y. S., and Cate, J. H. D. (2014) Overcoming inefficient cellobiose fermentation by cellobiose phosphorylase in the presence of xylose. Biotechnology for Biofuels 7 Bae, Y. H., Kang, K. H., Jin, Y. S., and Seo, J. H. (2014) Molecular cloning and expression of fungal cellobiose transporters and β-glucosidases conferring efficient cellobiose fermentation in Saccharomyces cerevisiae. Journal of Biotechnology 169, 34-41 2013 Wei, N., Xu, H., Kim, S. R., and Jin, Y. S. (2013) Deletion of FPS1, encoding aquaglyceroporin Fps1p, improves xylose fermentation by engineered Saccharomyces cerevisiae. Applied and Environmental Microbiology 79, 3193-3201 Wei, N., Quarterman, J., Kim, S. R., Cate, J. H. D., and Jin, Y. S. (2013) Enhanced biofuel production through coupled acetic acid and xylose consumption by engineered yeast. Nature Communications 4 Link, News Release from Natureasia, Inside Illinois, BBC News Wei, N., Quarterman, J., and Jin, Y. S. (2013) Marine macroalgae: An untapped resource for producing fuels and chemicals. Trends in Biotechnology 31, 70-77 Wang, Y., Li, X., Milne, C. B., Janssen, H., Lin, W., Phan, G., Hu, H., Jin, Y. S., Price, N. D., and Blascheka, H. P. (2013) Development of a gene knockout system using mobile group II introns (Targetron) and genetic disruption of acid production pathways in Clostridium beijerinckii. Applied and Environmental Microbiology 79, 5853-5863 Oh, E. J., Ha, S. J., Rin Kim, S., Lee, W. H., Galazka, J. M., Cate, J. H. D., and Jin, Y. S. (2013) Enhanced xylitol production through simultaneous co-utilization of cellobiose and xylose by engineered Saccharomyces cerevisiae. Metabolic Engineering 15, 226-234 Li, S., Ha, S. J., Kim, H. J., Galazka, J. M., Cate, J. H. D., Jin, Y. S., and Zhao, H. (2013) Investigation of the functional role of aldose 1-epimerase in engineered cellobiose utilization. Journal of Biotechnology 168, 1-6 Lee, W. H., Nan, H., Kim, H. J., and Jin, Y. S. (2013) Simultaneous saccharification and fermentation by engineered Saccharomyces cerevisiae without supplementing extracellular β-glucosidase. Journal of Biotechnology 167, 316-322 Lee, W. H., Kim, M. D., Jin, Y. S., and Seo, J. H. (2013) Engineering of NADPH regenerators in Escherichia coli for enhanced biotransformation. Applied Microbiology and Biotechnology 97, 2761-2772 Lee, K. S., Kim, J. S., Heo, P., Yang, T. J., Sung, Y. J., Cheon, Y., Koo, H. M., Yu, B. J., Seo, J. H., Jin, Y. S., Park, J. C., and Kweon, D. H. (2013) Characterization of Saccharomyces cerevisiae promoters for heterologous gene expression in Kluyveromyces marxianus. Applied Microbiology and Biotechnology 97, 2029-2041 Kim, S. R., Skerker, J. M., Kang, W., Lesmana, A., Wei, N., Arkin, A. P., and Jin, Y. S. (2013) Rational and evolutionary engineering approaches uncover a small set of genetic changes efficient for rapid xylose fermentation in Saccharomyces cerevisiae. PLoS ONE 8 Kim, S. R., Park, Y. C., Jin, Y. S., and Seo, J. H. (2013) Strain engineering of Saccharomyces cerevisiae for enhanced xylose metabolism. Biotechnology Advances 31, 851-861 Kim, S. R., Lee, K. S., Kong, I. I., Lesmana, A., Lee, W. H., Seo, J. H., Kweon, D. H., and Jin, Y. S. (2013) Construction of an efficient xylose-fermenting diploid Saccharomyces cerevisiae strain through mating of two engineered haploid strains capable of xylose assimilation. Journal of Biotechnology 164, 105-111 Kim, S. R., Kwee, N. R., Kim, H., and Jin, Y. S. (2013) Feasibility of xylose fermentation by engineered Saccharomyces cerevisiae overexpressing endogenous aldose reductase (GRE3), xylitol dehydrogenase (XYL2), and xylulokinase (XYL3) from Scheffersomyces stipitis. FEMS Yeast Research 13, 312-321 Kim, S. J., Seo, S. O., Jin, Y. S., and Seo, J. H. (2013) Production of 2,3-butanediol by engineered Saccharomyces cerevisiae. Bioresource Technology 146, 274-281 Kim, H. J., Turner, T. L., and Jin, Y. S. (2013) Combinatorial genetic perturbation to refine metabolic circuits for producing biofuels and biochemicals. Biotechnology Advances 31, 976-985 Kim, H. J., Lee, H. R., Kim, C. S., Jin, Y. S., and Seo, J. H. (2013) Investigation of protein expression profiles of erythritol-producing Candida magnoliae in response to glucose perturbation. Enzyme and Microbial Technology 53, 174-180 Ha, S. J., Kim, S. R., Kim, H., Du, J., Cate, J. H. D., and Jin, Y. S. (2013) Continuous co-fermentation of cellobiose and xylose by engineered Saccharomyces cerevisiae. Bioresource Technology 149, 525-531 Ha, S. J., Kim, H., Lin, Y., Jang, M. U., Galazka, J. M., Kim, T. J., Cate, J. H. D., and Jin, Y. S. (2013) Single amino acid substitutions in HXT2.4 from Scheffersomyces stipitis lead to improved cellobiose fermentation by engineered Saccharomyces cerevisiae. Applied and Environmental Microbiology 79, 1500-1507 Ha, S. J., Galazka, J. M., Joong Oh, E., Kordić, V., Kim, H., Jin, Y. S., and Cate, J. H. D. (2013) Energetic benefits and rapid cellobiose fermentation by Saccharomyces cerevisiae expressing cellobiose phosphorylase and mutant cellodextrin transporters. Metabolic Engineering 15, 134-143 Guo, B., Zhang, Y., Yu, G., Lee, W. H., Jin, Y. S., and Morgenroth, E. (2013) Two-stage acidic-alkaline hydrothermal pretreatment of lignocellulose for the high recovery of cellulose and hemicellulose sugars. Applied Biochemistry and Biotechnology 169, 1069-1087 2012 Lee, W. H., Seo, S. O., Bae, Y. H., Nan, H., Jin, Y. S., and Seo, J. H. (2012) Isobutanol production in engineered Saccharomyces cerevisiae by overexpression of 2-ketoisovalerate decarboxylase and valine biosynthetic enzymes. Bioprocess and Biosystems Engineering 35, 1467-1475 Lee, W. H., Pathanibul, P., Quarterman, J., Jo, J. H., Han, N. S., Miller, M. J., Jin, Y. S., and Seo, J. H. (2012) Whole cell biosynthesis of a functional oligosaccharide, 2'-fucosyllactose, using engineered Escherichia coli. Microbial Cell Factories 11, 48 Kim, S. R., Ha, S. J., Wei, N., Oh, E. J., and Jin, Y. S. (2012) Simultaneous co-fermentation of mixed sugars: A promising strategy for producing cellulosic ethanol. Trends in Biotechnology 30, 274-282 Kim, S. R., Ha, S. J., Kong, I. I., and Jin, Y. S. (2012) High expression of XYL2 coding for xylitol dehydrogenase is necessary for efficient xylose fermentation by engineered Saccharomyces cerevisiae. Metabolic Engineering 14, 336-343 Jin, Y. S., and Cate, J. H. D. (2012) Model-guided strain improvement: Simultaneous hydrolysis and co-fermentation of cellulosic sugars. Biotechnology Journal 7, 328-329 Guo, B., Zhang, Y., Ha, S. J., Jin, Y. S., and Morgenroth, E. (2012) Combined biomimetic and inorganic acids hydrolysis of hemicellulose in Miscanthus for bioethanol production. Bioresource Technology 110, 278-287 Cha, C., Kim, S. R., Jin, Y. S., and Kong, H. (2012) Tuning structural durability of yeast-encapsulating alginate gel beads with interpenetrating networks for sustained bioethanol production. Biotechnology and Bioengineering 109, 63-73 Milne, C. B., Eddy, J. A., Raju, R., Ardekani, S., Kim, P. J., Senger, R. S., Jin, Y. S., Blaschek, H. P., and Price, N. D. (2011) Metabolic network reconstruction and genome-scale model of butanol-producing strain Clostridium beijerinckii NCIMB 8052. BMC Systems Biology 5 2011 Lu, C. H., Choi, J. H., Engelmann Moran, N., Jin, Y. S., and Erdman, J. W. (2011) Laboratory-scale production of 13C-labeled lycopene and phytoene by bioengineered Escherichia coli. Journal of Agricultural and Food Chemistry 59, 9996-10005 Lee, K. S., Hong, M. E., Jung, S. C., Ha, S. J., Yu, B. J., Koo, H. M., Park, S. M., Seo, J. H., Kweon, D. H., Park, J. C., and Jin, Y. S. (2011) Improved galactose fermentation of Saccharomyces cerevisiae through inverse metabolic engineering. Biotechnology and Bioengineering 108, 621-631 Kim, J. S., Heo, P., Yang, T. J., Lee, K. S., Jin, Y. S., Kim, S. K., Shin, D., and Kweon, D. H. (2011) Bacterial persisters tolerate antibiotics by not producing hydroxyl radicals. Biochemical and Biophysical Research Communications 413, 105-110 Ha, S. J., Wei, Q., Kim, S. R., Galazka, J. M., Cate, J., and Jin, Y. S. (2011) Cofermentation of cellobiose and galactose by an engineered Saccharomyces cerevisiae Strain. Applied and Environmental Microbiology 77, 5822-5825 Link, Related News Ha, S. J., Kim, S. R., Choi, J. H., Park, M. S., and Jin, Y. S. (2011) Xylitol does not inhibit xylose fermentation by engineered Saccharomyces cerevisiae expressing xylA as severely as it inhibits xylose isomerase reaction in vitro. Applied Microbiology and Biotechnology 92, 77-84 Ha, S. J., Galazka, J. M., Kim, S. R., Choi, J. H., Yang, X., Seo, J. H., Glass, N. L., Cate, J. H. D., and Jin, Y. S. (2011) Engineered Saccharomyces cerevisiae capable of simultaneous cellobiose and xylose fermentation. Proceedings of the National Academy of Sciences of the United States of America 108, 516-521 Link,In This Issue-PNAS, Related News 2010 Kim, S. R., Lee, K. S., Choi, J. H., Ha, S. J., Kweon, D. H., Seo, J. H., and Jin, Y. S. (2010) Repeated-batch fermentations of xylose and glucose-xylose mixtures using a respiration-deficient Saccharomyces cerevisiae engineered for xylose metabolism. Journal of Biotechnology 150, 404-407 Jung, S. C., Smith, C. L., Lee, K. S., Hong, M. E., Kweon, D. H., Stephanopoulos, G., and Jin, Y. S. (2010) Restoration of growth phenotypes of Escherichia coli DH5α in minimal media through reversal of a point mutation in purB. Applied and Environmental Microbiology 76, 6307-6309 Related News1, Related News2 Hong, M. E., Lee, K. S., Yu, B. J., Sung, Y. J., Park, S. M., Koo, H. M., Kweon, D. H., Park, J. C., and Jin, Y. S. (2010) Identification of gene targets eliciting improved alcohol tolerance in Saccharomyces cerevisiae through inverse metabolic engineering. Journal of Biotechnology 149, 52-59 Related News 2009 Tyo, K. E. J., Espinoza, F. A., Stephanopoulos, G., and Jin, Y. S. (2009) Identification of gene disruptions for increased poly-3-hydroxybutyrate accumulation in Synechocystis PCC 6803. Biotechnology Progress 25, 1236-1243 Shin, J. Y., Shin, J. I., Kim, J. S., Yang, Y. S., Hwang, Y., Yang, J. S., Shin, D., Seo, J. H., Jin, Y. S., Park, Y. C., Hwang, J. S., and Kweon, D. H. (2009) Assembly of Coenzyme Q10 nanostructure resembling nascent discoidal high density lipoprotein particle. Biochemical and Biophysical Research Communications 388, 217-221 Lee, K., Shin, J. Y., Yang, Y. S., Shin, J. I., Park, Y. C., Seo, J. H., Park, T. H., Shin, C. S., Jin, Y. S., and Kweon, D. H. (2009) Towards a microarray of functional membrane proteins: Assembly of a surface-attachable, membrane-protein-anchored membrane structure using apolipoprotein A-1. Enzyme and Microbial Technology 44, 217-222 Lee, J., Seo, E., Kweon, D. H., Park, K., and Jin, Y. S. (2009) Fermentation of rice bran and defatted rice bran for butanol production using Clostridium beijerinckii NCIMB 8052. Journal of Microbiology and Biotechnology 19, 482-490 2008 Lee, K. S., Shin, J. Y., Jang, Y. H., Kweon, D. H., Park, K. M., and Jin, Y. S. (2008) Production of casein phosphopeptides using Streptococcus faecalis var. liquefaciens cell immobilization. KSBB Journal 23, 59-64 Jung, C. H., Yang, Y. S., Kim, J. S., Shin, J. I., Jin, Y. S., Shin, J. Y., Lee, J. H., Chung, K. M., Hwang, J. S., Oh, J. M., Shin, Y. K., and Kweon, D. H. (2008) A search for synthetic peptides that inhibit soluble N-ethylmaleimide sensitive-factor attachment receptor-mediated membrane fusion. FEBS Journal 275, 3051-3063 2007 and before Jung, S. C., Chung, C. Y., Kim, J. S., Kweon, D. H., Park, K. M., and Jin, Y. S. (2007) Policosanol production from rice bran oil byproducts. Food Engineering Progress 11, 337-347 Jin, Y. S., and Stephanopoulos, G. (2007) Multi-dimensional gene target search for improving lycopene biosynthesis in Escherichia coli. Metabolic Engineering 9, 337-347 Jeffries, T. W., Grigoriev, I. V., Grimwood, J., Laplaza, J. M., Aerts, A., Salamov, A., Schmutz, J., Lindquist, E., Dehal, P., Shapiro, H., Jin, Y. S., Passoth, V., and Richardson, P. M. (2007) Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis. Nature Biotechnology 25, 319-326 Laplaza, J. M., Torres, B. R., Jin, Y. S., and Jeffries, T. W. (2006) Sh ble and Cre adapted for functional genomics and metabolic engineering of Pichia stipitis. Enzyme and Microbial Technology 38, 741-747 Kim, J. S., Lee, K. W., Jin, Y. S., Yoo, S. J., Jung, K. Y., Lee, J. W., Lee, S. Y., and Hwang, D. H. (2006) Standardization on metabolic and biological pathway. Bioinformatics and Biosystems 1, 196-200 Jin, Y. S., Cruz, J., and Jeffries, T. W. (2005) Xylitol production by a Pichia stipitis D-xylulokinase mutant. Applied Microbiology and Biotechnology 68, 42-45 Jin, Y. S., Alper, H., Yang, Y. T., and Stephanopoulos, G. (2005) Improvement of xylose uptake and ethanol production in recombinant Saccharomyces cerevisiae through an inverse metabolic engineering approach. Applied and Environmental Microbiology 71, 8249-8256 Alper, H., Jin, Y. S., Moxley, J. F., and Stephanopoulos, G. (2005) Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli. Metabolic Engineering 7, 155-164 Jin, Y. S., Laplaza, J. M., and Jeffries, T. W. (2004) Saccharomyces cerevisiae engineered for xylose metabolism exhibits a respiratory response. Applied and Environmental Microbiology 70, 6816-6825 Jin, Y. S., and Jeffries, T. W. (2004) Stoichiometric network constraints on xylose metabolism by recombinant Saccharomyces cerevisiae. Metabolic Engineering 6, 229-238 Jeffries, T. W., and Jin, Y. S. (2004) Metabolic engineering for improved fermentation of pentoses by yeasts. Applied Microbiology and Biotechnology 63, 495-509 Jin, Y. S., Ni, H., Laplaza, J. M., and Jeffries, T. W. (2003) Optimal growth and ethanol production from xylose by recombinant Saccharomyces cerevisiae require moderate D-xylulokinase activity. Applied and Environmental Microbiology 69, 495-503 Jin, Y. S., and Jeffries, T. W. (2003) Changing flux of xylose metabolites by altering expression of xylose reductase and xylitol dehydrogenase in recombinant Saccharomyces cerevisiae. Applied Biochemistry and Biotechnology 106, 277-286 Jin, Y. S., Jones, S., Shi, N. Q., and Jeffries, T. W. (2002) Molecular cloning of XYL3 (D-xylulokinase) from Pichia stipitis and characterization of its physiological function. 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