Jin:Publications

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#Wei, N., Xu, H., Kim, S. R., and Jin, Y. S. (2013) Deletion of FPS1, encoding aquaglyceroporin Fps1p, improves xylose fermentation by engineered Saccharomyces cerevisiae. Applied and Environmental Microbiology 79, 3193-3201
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==Peer-reviewed articles==
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#Wei, N., Quarterman, J., and Jin, Y. S. (2013) Marine macroalgae: an untapped resource for producing fuels and chemicals. Trends in Biotechnology 31, 70-77
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#Wang, Y., Li, X., Milne, C. B., Janssen, H., Lin, W., Phan, G., Hu, H., Jin, Y. S., Price, N. D., and Blaschek, H. P. (2013) Development of a gene knockout system using mobile group II introns (Targetron) and genetic disruption of acid production pathways in Clostridium beijerinckii. Applied and Environmental Microbiology 79, 5853-5863
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===2013===
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#Oh, E. J., Ha, S. J., Rin Kim, S., Lee, W. H., Galazka, J. M., Cate, J. H., and Jin, Y. S. (2013) Enhanced xylitol production through simultaneous co-utilization of cellobiose and xylose by engineered Saccharomyces cerevisiae. Metabolic Engineering 15, 226-234
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*Kim, H.J., Lee, H.R., Kim, C.S., Jin, Y.S., Seo, J.H. Investigation of protein expression profiles of erythritol-producing ''Candida magnoliae'' in response to glucose perturbation. Enzyme and Microbial Technology [http://www.sciencedirect.com/science/article/pii/S0141022913000732 Link]
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#Na, W., Quarterman, J., Kim, S. R., Cate, J. H., and Jin, Y. S. (2013) Enhanced biofuel production through coupled acetic acid and xylose consumption by engineered yeast. Nature Communications
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#Li, S., Ha, S. J., Kim, H. J., Galazka, J. M., Cate, J. H., Jin, Y. S., and Zhao, H. (2013) Investigation of the functional role of aldose 1-epimerase in engineered cellobiose utilization. Journal of Biotechnology 168, 1-6
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*Kim, H.J., Turner, T.L., Jin, Y.S. Combinatorial genetic perturbation to refince metabolic circuits for producing biofuels and biochemicals. Biotechnology Advances (In press)
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#Lee, W. H., Nan, H., Kim, H. J., and Jin, Y. S. (2013) Simultaneous saccharification and fermentation by engineered Saccharomyces cerevisiae without supplementing extracellular beta-glucosidase. Journal of Biotechnology 167, 316-322
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#Lee, W. H., Kim, M. D., Jin, Y. S., and Seo, J. H. (2013) Engineering of NADPH regenerators in Escherichia coli for enhanced biotransformation. Applied Microbiology and Biotechnology 97, 2761-2772
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*Kim, S.J., Seo, S.O., Jin, Y.S. & Seo, J.H. Production of 2,3-butanediol by engineered ''Saccharomyces cerevisiae''. Bioresource Technology [http://www.sciencedirect.com/science/article/pii/S0960852413011498 Link]
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#Lee, K. S., Kim, J. S., Heo, P., Yang, T. J., Sung, Y. J., Cheon, Y., Koo, H. M., Yu, B. J., Seo, J. H., Jin, Y. S., Park, J. C., and Kweon, D. H. (2013) Characterization of Saccharomyces cerevisiae promoters for heterologous gene expression in Kluyveromyces marxianus. Applied Microbiology and Biotechnology 97, 2029-2041
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#Kim, S. R., Skerker, J. M., Kang, W., Lesmana, A., Wei, N., Arkin, A. P., and Jin, Y. S. (2013) Rational and evolutionary engineering approaches uncover a small set of genetic changes efficient for rapid xylose fermentation in Saccharomyces cerevisiae. PloS ONE 8, e57048
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*Wang, Y., Li, X.Z., Milne, C., Janssen, H., Lin, W., Phan, G., Hu, H., Jin, Y.S., Price, N. & Blaschek, H. Development of a gene knockout system using mobile group II introns (Targetron) and genetic disruption of acid production pathways in ''Clostridium beijerinckii''. Applied and Environmental Microbiology [http://aem.asm.org/content/early/2013/07/15/AEM.00971-13.short Link] 
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#Kim, S. R., Park, Y. C., Jin, Y. S., and Seo, J. H. (2013) Strain engineering of Saccharomyces cerevisiae for enhanced xylose metabolism. Biotechnology Advances 31, 851-861
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#Kim, S. R., Lee, K. S., Kong, II, Lesmana, A., Lee, W. H., Seo, J. H., Kweon, D. H., and Jin, Y. S. (2013) Construction of an efficient xylose-fermenting diploid Saccharomyces cerevisiae strain through mating of two engineered haploid strains capable of xylose assimilation. Journal of Biotechnology 164, 105-111
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*Lee, W.H., Nan, H., Kim, H.J. & Jin, Y.S. Simultaneous saccharification and fermentation by engineered ''Saccharomyces cerevisiae'' without supplementing extracellular beta-glucosidase. Journal of Biotechnology [http://www.sciencedirect.com/science/article/pii/S0168165613002721 Link]
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#Kim, S. R., Kwee, N. R., Kim, H., and Jin, Y. S. (2013) Feasibility of xylose fermentation by engineered Saccharomyces cerevisiae overexpressing endogenous aldose reductase (GRE3), xylitol dehydrogenase (XYL2), and xylulokinase (XYL3) from Scheffersomyces stipitis. FEMS Yeast Research 13, 312-321
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#Kim, S. J., Seo, S. O., Jin, Y. S., and Seo, J. H. (2013) Production of 2,3-butanediol by engineered Saccharomyces cerevisiae. Bioresource Technology 146, 274-281
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*Kim, S.R., Park, Y.C., Jin, Y.S., & Seo, J.H. Strain engineering of ''Saccharomyces cerevisiae'' for enhanced xylose metabolism. Biotechnology Advances (accepted)
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#Kim, H. J., Turner, T. L., and Jin, Y. S. (2013) Combinatorial genetic perturbation to refine metabolic circuits for producing biofuels and biochemicals. Biotechnology Advances 31, 976-985
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#Kim, H. J., Lee, H. R., Kim, C. S., Jin, Y. S., and Seo, J. H. (2013) Investigation of protein expression profiles of erythritol-producing Candida magnoliae in response to glucose perturbation. Enzyme and Microbial Technology 53, 174-180
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*Wei, N., Xu, H., Kim, S.R., & Jin, Y.S. Deletion of ''FPS1'' coding for aquaglyceroporin Fps1p improves xylose fermentation by engineered ''Saccharomyces cerevisiae''. Applied and Environmental Microbiology [http://aem.asm.org/content/79/10/3193.short Link]
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#Ha, S. J., Kim, S. R., Kim, H. J., Du, J., Cate, J. H., and Jin, Y. S. (2013) Continuous co-fermentation of cellobiose and xylose by engineered Saccharomyces cerevisiae. Bioresource Technology
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#Ha, S. J., Kim, H., Lin, Y., Jang, M. U., Galazka, J. M., Kim, T. J., Cate, J. H., and Jin, Y. S. (2013) Single amino acid substitutions in HXT2.4 from Scheffersomyces stipitis lead to improved cellobiose fermentation by engineered Saccharomyces cerevisiae. Applied and Environmental Microbiology 79, 1500-1507
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*Kim, S.R., Kwee, N.R., Kim, H.J. & Jin, Y.S. Feasibility of xylose fermentation by engineered ''Saccharomyces cerevisiae'' overexpressing endogenous aldose reductase (''GRE3''), xylitol dehydrogenase (''XYL2'') and xylulokinase (''XYL3'') from ''Scheffersomyces stipitis''. FEMS Yeast Research [http://onlinelibrary.wiley.com/doi/10.1111/1567-1364.12036/abstract Link]
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#Ha, S. J., Galazka, J. M., Oh, E. J., Kordic, V., Kim, H., Jin, Y. S., and Cate, J. H. (2013) Energetic benefits and rapid cellobiose fermentation by Saccharomyces cerevisiae expressing cellobiose phosphorylase and mutant cellodextrin transporters. Metabolic Engineering 15, 134-143
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#Guo, B., Zhang, Y., Yu, G., Lee, W. H., Jin, Y. S., and Morgenroth, E. (2013) Two-stage acidic-alkaline hydrothermal pretreatment of lignocellulose for the high recovery of cellulose and hemicellulose sugars. Applied Biochemistry and Biotechnology 169, 1069-1087
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*Lee, W.H., Kim, M.D., Jin, Y.S. & Seo, J.H. Engineering of NADPH regenerators in ''Escherichia coli'' for enhanced biotransformation. Applied Microbiology and Biotechnology [http://link.springer.com/article/10.1007/s00253-013-4750-z Link]
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#Lee, W. H., Seo, S. O., Bae, Y. H., Nan, H., Jin, Y. S., and Seo, J. H. (2012) Isobutanol production in engineered Saccharomyces cerevisiae by overexpression of 2-ketoisovalerate decarboxylase and valine biosynthetic enzymes. Bioprocess and Biosystems Engineering 35, 1467-1475
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#Lee, W. H., Pathanibul, P., Quarterman, J., Jo, J. H., Han, N. S., Miller, M. J., Jin, Y. S., and Seo, J. H. (2012) Whole cell biosynthesis of a functional oligosaccharide, 2'-fucosyllactose, using engineered Escherichia coli. Microbial Cell Factories 11, 48
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*Kim, S.R., Skerker, J.M., Kang, W., Lesmana, A., Wei, N., Arkin, A.P. & Jin, Y.S. Rational and evolutionary engineering approaches uncover a small set of genetic changes efficient for rapid xylose fermentation in ''Saccharomyces cerevisiae''. PLOS One [http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0057048?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+plosone%2FPLoSONE+(PLoS+ONE+Alerts%3A+New+Articles) Link]
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#Kim, S. R., Ha, S. J., Wei, N., Oh, E. J., and Jin, Y. S. (2012) Simultaneous co-fermentation of mixed sugars: a promising strategy for producing cellulosic ethanol. Trends in Biotechnology 30, 274-282
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#Kim, S. R., Ha, S. J., Kong, II, and Jin, Y. S. (2012) High expression of XYL2 coding for xylitol dehydrogenase is necessary for efficient xylose fermentation by engineered Saccharomyces cerevisiae. Metabolic Engineering 14, 336-343
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*Kim, S.R., Lee, K.S., Kong, I.K., Lesmana, A., Lee, W.H., Seo, J.H., Kweon, D.H. & Jin, Y.S. Construction of an efficient xylose-fermenting diploid ''Saccharomyces cerevisiae'' strain through mating of two engineered haploid strains capable of xylose assimilation. Journal of Biotechnology [http://www.ncbi.nlm.nih.gov/pubmed/23376240 Link]
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#Jin, Y. S., and Cate, J. H. (2012) Model-guided strain improvement: simultaneous hydrolysis and co-fermentation of cellulosic sugars. Biotechnology Journal 7, 328-329
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#Guo, B., Zhang, Y., Ha, S. J., Jin, Y. S., and Morgenroth, E. (2012) Combined biomimetic and inorganic acids hydrolysis of hemicellulose in Miscanthus for bioethanol production. Bioresource Technology 110, 278-287
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===2012===
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#Cha, C., Kim, S. R., Jin, Y. S., and Kong, H. (2012) Tuning structural durability of yeast-encapsulating alginate gel beads with interpenetrating networks for sustained bioethanol production. Biotechnology and Bioengineering 109, 63-73
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*Guo, B., Zhang, Y., Yu, G., Lee, W.H., Jin, Y.S.& Morgenroth, E., Two-stage acidic-alkaline hydrothermal pretreatment of lignocellulose for the high recovery of cellulose and hemicellulose sugars. Applied Biochemistry and Biotechnology [http://link.springer.com/article/10.1007%2Fs12010-012-0038-5 Link]
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#Milne, C. B., Eddy, J. A., Raju, R., Ardekani, S., Kim, P. J., Senger, R. S., Jin, Y. S., Blaschek, H. P., and Price, N. D. (2011) Metabolic network reconstruction and genome-scale model of butanol-producing strain Clostridium beijerinckii NCIMB 8052. BMC Systems Biology 5, 130
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#Lu, C. H., Choi, J. H., Engelmann Moran, N., Jin, Y. S., and Erdman, J. W., Jr. (2011) Laboratory-scale production of 13C-labeled lycopene and phytoene by bioengineered Escherichia coli. Journal of Agricultural and Food Chemistry 59, 9996-10005
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*Ha,S.J., Kim, H., Lin, Y., Jang, M.U., Galazka, J.M., Kim, T.J., Cate. J.H. & Jin, Y.S. Single amino acid substitutions of HXT2.4 from ''Scheffersomyces stipitis'' lead to improved cellobiose fermentation by engineered ''Saccharomyces cerevisiae''. Applied and Environmental Microbiology [http://aem.asm.org/content/79/5/1500.abstract Link]
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#Lee, K. S., Hong, M. E., Jung, S. C., Ha, S. J., Yu, B. J., Koo, H. M., Park, S. M., Seo, J. H., Kweon, D. H., Park, J. C., and Jin, Y. S. (2011) Improved galactose fermentation of Saccharomyces cerevisiae through inverse metabolic engineering. Biotechnology and Bioengineering 108, 621-631
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#Kim, J. S., Heo, P., Yang, T. J., Lee, K. S., Jin, Y. S., Kim, S. K., Shin, D., and Kweon, D. H. (2011) Bacterial persisters tolerate antibiotics by not producing hydroxyl radicals. Biochemical and Biophysical Research Communications 413, 105-110
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*Ha, S.J., Galazka, J.M., Oh, E.J., Kordic, V., Kim, H., Jin, Y.S., & Cate, J.H. Energetic benefits and rapid cellobiose fermentation by ''Saccharomyces cerevisiae'' expressing cellobiose phosphorylase and mutant cellodextrin transporters. Metabolic Engineering [http://www.sciencedirect.com/science/article/pii/S109671761200122X Link]
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#Ha, S. J., Wei, Q., Kim, S. R., Galazka, J. M., Cate, J. H., and Jin, Y. S. (2011) Cofermentation of cellobiose and galactose by an engineered Saccharomyces cerevisiae strain. Applied and Environmental Microbiology 77, 5822-5825
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#Ha, S. J., Kim, S. R., Choi, J. H., Park, M. S., and Jin, Y. S. (2011) Xylitol does not inhibit xylose fermentation by engineered Saccharomyces cerevisiae expressing xylA as severely as it inhibits xylose isomerase reaction in vitro. Applied Microbiology and Biotechnology 92, 77-84
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*Wei, N. Quarterman, J., & Jin, Y.S. Marine macroalgae: an untapped resource for producing fuels and chemicals. Trends in Biotechnol. [http://www.cell.com/trends/biotechnology/abstract/S0167-7799(12)00189-8 Link]
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#Ha, S. J., Galazka, J. M., Kim, S. R., Choi, J. H., Yang, X., Seo, J. H., Glass, N. L., Cate, J. H., and Jin, Y. S. (2011) Engineered Saccharomyces cerevisiae capable of simultaneous cellobiose and xylose fermentation. Proceedings of the National Academy of Sciences of the United States of America 108, 504-509
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#Kim, S. R., Lee, K. S., Choi, J. H., Ha, S. J., Kweon, D. H., Seo, J. H., and Jin, Y. S. (2010) Repeated-batch fermentations of xylose and glucose-xylose mixtures using a respiration-deficient Saccharomyces cerevisiae engineered for xylose metabolism. Journal of Biotechnology 150, 404-407
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*Oh, E.J., Ha, S.J., Kim, S.R., Lee, W.H., Galazka, J.M., Cate, J.H. & Jin, Y.S. Enhanced xylitol production through simultaneous co-utilization of cellobiose and xylose by engineered ''Saccharomyces cerevisiae''. Metabolic Engineering [http://www.sciencedirect.com/science/article/pii/S1096717612000985 Link]
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#Jung, S. C., Smith, C. L., Lee, K. S., Hong, M. E., Kweon, D. H., Stephanopoulos, G., and Jin, Y. S. (2010) Restoration of growth phenotypes of Escherichia coli DH5 in minimal media through reversal of a point mutation in purB. Applied and Environmental Microbiology 76, 6307-6309
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#Hong, M. E., Lee, K. S., Yu, B. J., Sung, Y. J., Park, S. M., Koo, H. M., Kweon, D. H., Park, J. C., and Jin, Y. S. (2010) Identification of gene targets eliciting improved alcohol tolerance in Saccharomyces cerevisiae through inverse metabolic engineering. Journal of Biotechnology 149, 52-59
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*Lee, K.S., Kim, J.S., Heo, P., Yang, T.J., Sung, Y.J., Cheon, Y., Koo, H.M., Yu, B.J., Seo, J.H., Jin, Y.S., Park, J.C., Kweon, D.H. Characterization of ''Saccharomyces cerevisiae'' promoters for heterologous gene expression in ''Kluyveromyces marxianus''. Appl Microbiol Biotechnol [http://www.ncbi.nlm.nih.gov/pubmed/22911091 Link]
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#Tyo, K. E., Jin, Y. S., Espinoza, F. A., and Stephanopoulos, G. (2009) Identification of gene disruptions for increased poly-3-hydroxybutyrate accumulation in Synechocystis PCC 6803. Biotechnology Progress 25, 1236-1243
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#Shin, J. Y., Shin, J. I., Kim, J. S., Yang, Y. S., Hwang, Y., Yang, J. S., Shin, D., Seo, J. H., Jin, Y. S., Park, Y. C., Hwang, J. S., and Kweon, D. H. (2009) Assembly of Coenzyme Q10 nanostructure resembling nascent discoidal high density lipoprotein particle. Biochemical and Biophysical Research Communications 388, 217-221
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*Lee, W.H., Pathanibul, P., Quarterman, J., Jo, J.H., Han, N.S., Miller, M.J., Jin, Y.S.& Seo, J.H. Whole cell biosynthesis of a functional oligosaccharide, 2-fucosyllactose, using engineered ''Escherichia coli''. Microbial Cell Factories 11, 48 [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442965/?report=abstract Link]
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#Lee, K., Shin, J. Y., Yang, Y. S., Shin, J. I., Park, Y. C., Seo, J. H., Park, T. H., Shin, C. S., Jin, Y. S., and Kweon, D. H. (2009) Towards a microarray of functional membrane proteins: Assembly of a surface-attachable, membrane-protein-anchored membrane structure using apolipoprotein A-1. Enzyme and Microbial Technology 44, 217-222
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#Lee, J., Seo, E., Kweon, D. H., Park, K., and Jin, Y. S. (2009) Fermentation of rice bran and defatted rice bran for butanol 5 production using Clostridium beijerinckii NCIMB 8052. Journal of Microbiology and Biotechnology 19, 482-490
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*Lee, W.H., Seo, S.O., Bae, Y.H., Nan, H., Jin, Y.S.& Seo, J.H. Isobutanol production in engineered ''Saccharomyces cerevisiae'' by overexpression of 2-ketoisovalerate decarboxylase and valine biosynthetic enzymes. Bioprocess and Biosystems Engineering 35, 1467-75 [http://www.ncbi.nlm.nih.gov/pubmed/22543927 Link]
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#Lee, K. S., Chang, E. H., Shin, J. Y., Kweon, D. H., Park, K. M., and Jin, Y. S. (2008) Production of casein phosphopeptides using Streptococcus faecalis var. liquefaciens cell immobilization. Korean Journal of Biotechnology and Bioengineering 23, 59-64
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#Jung, C. H., Yang, Y. S., Kim, J. S., Shin, J. I., Jin, Y. S., Shin, J. Y., Lee, J. H., Chung, K. M., Hwang, J. S., Oh, J. M., Shin, Y. K., and Kweon, D. H. (2008) A search for synthetic peptides that inhibit soluble N-ethylmaleimide sensitive-factor attachment receptor-mediated membrane fusion. The FEBS journal 275, 3051-3063
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*Kim, S.R., Ha, S.J., Kong, I.I., & Jin, Y.S. High expression of ''XYL2'' coding for xylitol dehydrogenase is necessary for efficient xylose fermentation by engineered ''Saccharomyces cerevisiae'' Metab. Eng. 14, 336-343 [http://www.ncbi.nlm.nih.gov/pubmed/22521925 Link]
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#Jung, S. C., Chung, C. Y., Kim, J. S., Kweon, D. H., Park, K. M., and Jin, Y. S. (2007) Policosanol production from rice bran oil byproducts. Food Engineering Progress 11, 293-297
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#Jin, Y. S., and Stephanopoulos, G. (2007) Multi-dimensional gene target search for improving lycopene biosynthesis in Escherichia coli. Metabolic Engineering 9, 337-347
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*Guo, B., Zhang, Y., Ha, S. J., Jin, Y.S.& Morgenroth, E. Combined biomimetic and inorganic acids hydrolysis of hemicellulose in Miscanthus for bioethanol production. Bioresource Technol 110,278-87 [http://dx.doi.org/10.1016/j.biortech.2012.01.133 Link]
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#Jeffries, T. W., Grigoriev, I. V., Grimwood, J., Laplaza, J. M., Aerts, A., Salamov, A., Schmutz, J., Lindquist, E., Dehal, P., Shapiro, H., Jin, Y. S., Passoth, V., and Richardson, P. M. (2007) Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis. Nature Biotechnology 25, 319-326
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#Laplaza, J. M., Torres, B. R., Jin, Y. S., and Jeffries, T. W. (2006) Sh ble and Cre adapted for functional genomics and metabolic engineering of Pichia stipitis. Enzyme and Microbial Technology 38, 741-747
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*Kim, S.R., Ha, S.J., Wei, N., Oh, E.J., & Jin, Y.S. Simultaneous co-fermenation of mixed sugars: a promising strategy for producing cellulosic ethnaol. Trend Biotechnol 30,274–282 [http://dx.doi.org/10.1016/j.tibtech.2012.01.005 Link]
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#Kim, J. S., Lee, K. W., Jin, Y. S., Yoo, S. J., Jung, K. Y., Lee, J. W., Lee, S. Y., and Hwang, D. H. (2006) Standardization on metabolic and biological pathway. Bioinformatics and Biosystems 1, 196-200
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#Jin, Y. S., Cruz, J., and Jeffries, T. W. (2005) Xylitol production by a Pichia stipitis D-xylulokinase mutant. Applied Microbiology and Biotechnology 68, 42-45
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*Jin, Y.S. & Cate, J.H. Model-guided strain improvement: Simultaneous hydrolysis and co-fermentation of cellulosic sugars. Biotechnol. J. 7,361-73. [http://onlinelibrary.wiley.com/doi/10.1002/biot.201100489/full Link]
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#Jin, Y. S., Alper, H., Yang, Y. T., and Stephanopoulos, G. (2005) Improvement of xylose uptake and ethanol production in recombinant Saccharomyces cerevisiae through an inverse metabolic engineering approach. Applied and Environmental Microbiology 71, 8249-8256
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#Alper, H., Jin, Y. S., Moxley, J. F., and Stephanopoulos, G. (2005) Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli. Metabolic Engineering 7, 155-164
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*Cha, C., Kim, S.R., Jin, Y.S. & Kong, H.J. Tuning structural durability of yeast-encapsulating alginate gel beads with interpenetrating networks for sustained bioethanol production. Biotechnol. Bioeng. 109,63-73 [http://onlinelibrary.wiley.com/doi/10.1002/bit.23258/abstract Link]
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#Jin, Y. S., Laplaza, J. M., and Jeffries, T. W. (2004) Saccharomyces cerevisiae engineered for xylose metabolism exhibits a respiratory response. Applied and Environmental Microbiology 70, 6816-6825
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#Jin, Y. S., and Jeffries, T. W. (2004) Stoichiometric network constraints on xylose metabolism by recombinant Saccharomyces cerevisiae. Metabolic Engineering 6, 229-238
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===2011===
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#Jeffries, T. W., and Jin, Y. S. (2004) Metabolic engineering for improved fermentation of pentoses by yeasts. Applied Microbiology and Biotechnology 63, 495-509
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#Jin, Y. S., Ni, H., Laplaza, J. M., and Jeffries, T. W. (2003) Optimal growth and ethanol production from xylose by recombinant Saccharomyces cerevisiae require moderate D-xylulokinase activity. Applied and Environmental Microbiology 69, 495-503
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*Lu, C.H., Choi, J.H., Engelmann Moran, N., Jin, Y.S. & Erdman, J. Laboratory-scale production of 13C-labeled lycopene and phytoene by bioengineered ''Escherichia''. J Agric Food Chem  [http://pubs.acs.org/doi/abs/10.1021/jf202599z Link]
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#Jin, Y. S., and Jeffries, T. W. (2003) Changing flux of xylose metabolites by altering expression of xylose reductase and xylitol dehydrogenase in recombinant Saccharomyces cerevisiae. Applied Biochemistry and Biotechnology 105 -108, 277-286
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#Jin, Y. S., Jones, S., Shi, N. Q., and Jeffries, T. W. (2002) Molecular cloning of XYL3 (D-xylulokinase) from Pichia stipitis and characterization of its physiological function. Applied and Environmental Microbiology 68, 1232-1239
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*Kim, J.S., Heo P., Yang. T.J., Lee, K.S., Jin Y.S., Kim, S. K., Shin, D. & Kweon, D.H. Bacterial persisters tolerate antibiotics by not producing hydroxyl radicals. Biochem. Biophys. Res. Commun. [http://www.ncbi.nlm.nih.gov/pubmed/21872573 Link]
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#Jin, Y. S., Lee, T. H., Choi, Y. D., Ryu, Y. W., and Seo, J. H. (2000) Conversion of xylose to ethanol by recombinant Saccharomyces cerevisiae containing genes for xylose reductase and xylitol dehydrogenase from Pichia stipitis. Journal of Microbiology and Biotechnology 10, 564-567
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#Jeffries, T. W., and Jin, Y. S. (2000) Ethanol and thermotolerance in the bioconversion of xylose by yeasts. Advances in Applied Microbiology 47, 221-268
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*Milne, C.B., Eddy, J.A., Raju, R., Ardekani,S., Kim, P.J., Senger, R. S., Jin, Y.S., Blaschek, H.P. & Price, N.D. Metabolic network reconstruction and genome-scale model of butanol-producing strain ''Clostridium beijerinckii'' NCIMB 8052 BMC Systems Biology 5:130. [http://www.biomedcentral.com/1752-0509/5/130 Link]
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*Ha, S.J., Wei, Q., Kim, S.R., Galazka, J., Cate, J.H. & Jin, Y.S. Co-fermentation of cellobiose and galactose by an engineered ''Saccharomyces cerevisiae''. Appl. Environ. Microbiol. 77, 5822-5826. [http://aem.asm.org/cgi/content/abstract/77/16/5822 Link], [http://www.dailycal.org/2011/08/30/team-doubles-efficiency-of-converting-seaweed-into-biofuel/ Related News]
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*Ha, S.J., Kim, S.R., Choi J.H., Park, M.S. & Jin Y.S. Xylitol does not inhibit xylose fermentation by engineered ''Saccharomyces cerevisiae'' expressing ''xylA'' as severely as it inhibits xylose isomerase reaction ''in vitro''. Appl Microbiol Biotechnol (in press) [http://www.springerlink.com/content/q8724640851x5u25/ Link]
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*Ha, S.J., Galazka J.M., Rin Kim S., Choi J.H., Yang X., Seo J.H., Louise Glass N., Cate J.H., & Jin Y.S.Engineered ''Saccharomyces cerevisiae'' capable of simultaneous cellobiose and xylose fermentation. Proc Natl Acad Sci U S A. 108, 504-509 (2011) [http://www.pnas.org/content/108/2/504.abstract Link], [http://openwetware.org/images/8/80/Ha_PNAS.pdf PDF],[http://openwetware.org/images/d/d3/Ha_PNAS_SI.pdf Supporting Information], [http://www.pnas.org/content/108/2/435.full In This Issue-PNAS], [http://www.physorg.com/news/2010-12-scientists-major-obstacles-cellulosic-biofuel.html Related News]
 +
 
 +
*Lee, K.S., Hong, M.E., Jung, S.C., Ha, S.J., Yu, B.J., Koo, H.M., Park, S.M., Seo, J.H., Kweon, D.H., Park, J.C. & Jin, Y.S. Improved galactose fermentation of ''Saccharomyces cerevisiae'' through inverse metabolic engineering. Biotechnol Bioeng. 108, 621-632. [http://dx.doi.org/10.1002/bit.22988 Link]
 +
 
 +
===2010===
 +
*Kim, S.R., Lee, K.S., Choi, J.H., Ha, S.J., Kweon, D.H., Seo, J.H. & Jin, Y.S. Repeated-batch fermentations of xylose and glucose-xylose mixtures using a respiration-deficient ''Saccharomyces cerevisiae'' engineered for xylose metabolism. J Biotechnol 150, 404-407 (2010). [http://dx.doi.org/10.1016/j.jbiotec.2010.09.962 Link]
 +
* Jung, S.C., Smith, C.L., Lee, K.S., Hong, M.E., Kweon, D.H., Stephanopoulos, G. & Jin, Y.S. Restoration of growth phenotypes of ''Escherichia coli'' DH5alpha in minimal media through reversal of a point mutation in ''purB''. Appl Environ Microbiol 76, 6307-6309 (2010). [http://dx.doi.org/10.1128/AEM.01210-10 Link], [http://www.sciencedaily.com/releases/2010/11/101111160547.htm Related News1], [http://www.biotechniques.com/news/The-key-to-the-meaning-of-life-Harder-better-faster-stronger-E.-coli/biotechniques-307403.html Related News2]
 +
* Hong, M.E., Lee, K.S., Yu, B.J., Sung, Y.J., Park, S.M., Koo, H.M., Kweon, D.H., Park, J.C. & Jin, Y.S. Identification of gene targets eliciting improved alcohol tolerance in ''Saccharomyces cerevisiae'' through inverse metabolic engineering. J Biotechnol 149, 52-59 (2010). [http://dx.doi.org/10.1016/j.jbiotec.2010.06.006 Link], [http://www.sciencedaily.com/releases/2010/08/100819112220.htm Related News]
 +
 
 +
===2009===
 +
* Tyo, K.E., Jin, Y.S., Espinoza, F.A. & Stephanopoulos, G. Identification of gene disruptions for increased poly-3-hydroxybutyrate accumulation in ''Synechocystis'' PCC 6803. Biotechnol Prog 25, 1236-1243 (2009). [http://dx.doi.org/10.1002/btpr.228 Link]
 +
* Shin, J.Y., Shin, J.I., Kim, J.S., Yang, Y.S., Hwang, Y., Yang, J.S., Shin, D., Seo, J.H., Jin, Y.S., Park, Y.C., Hwang, J.S. & Kweon, D.H. Assembly of Coenzyme Q10 nanostructure resembling nascent discoidal high density lipoprotein particle. Biochem Biophys Res Commun 388, 217-221 (2009).
 +
* Lee, K., Shin, J.Y., Yang, Y.S., Shin, J.I., Park, Y.C., Seo, J.H., Park, T.H., Shin, C.S., Jin, Y.S. & Kweon, D.H. Towards a microarray of functional membrane proteins: Assembly of a surface-attachable, membrane-protein-anchored membrane structure using apolipoprotein A-1. Enz. Microb Tech 44, 217-222 (2009).
 +
* Lee, J., Seo, E., Kweon, D.H., Park, K. & Jin, Y.S. Fermentation of rice bran and defatted rice rran for butanol production using Clostridium beijerinckii NCIMB 8052. J. Microbiol. Biotechnol. 19, 482-490 (2009).
 +
 
 +
===2008===
 +
* Lee, K.S., Chang, E.H., Shin, J.Y., Kweon, D.H., Park, K.M. & Jin, Y.S. Production of casein phosphopeptides using Streptococcus faecalis var. liquefaciens cell immobilization. Korean J Biotechnol Bioeng 23, 59-64 (2008).
 +
* Jung, C.H., Yang, Y.S., Kim, J.S., Shin, J.I., Jin, Y.S., Shin, J.Y., Lee, J.H., Chung, K.M., Hwang, J.S., Oh, J.M., Shin, Y.K. & Kweon, D.H. A search for synthetic peptides that inhibit soluble N-ethylmaleimide sensitive-factor attachment receptor-mediated membrane fusion. FEBS J 275, 3051-3063 (2008).
 +
===2006-2007===
 +
*Jung, S.C., Chung, C.Y., Kim, J.S., Kweon, D.H., Park, K.M. & Jin, Y.S. Policosanol production from rice bran oil byproducts. Food Eng Prog 11, 293-297 (2007)
 +
* Jin, Y.S. & Stephanopoulos, G. Multi-dimensional gene target search for improving lycopene biosynthesis in Escherichia coli. Metab Eng 9, 337-347 (2007).
 +
* Jeffries, T.W., Grigoriev, I.V., Grimwood, J., Laplaza, J.M., Aerts, A., Salamov, A., Schmutz, J., Lindquist, E., Dehal, P., Shapiro, H., Jin, Y.S., Passoth, V. & Richardson, P.M. Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis. Nat Biotechnol 25, 319-326 (2007).
 +
* Laplaza, J.M., Torres, B.R., Jin, Y.S. & Jeffries, T.W. Sh ble and Cre adapted for functional genomics and metabolic engineering of Pichia stipitis. Enz Microb Tech 38, 741-747 (2006).
 +
* Jin, Y.S., Cruz, J. & Jeffries, T.W. Xylitol production by a Pichia stipitis D-xylulokinase mutant. Appl Microbiol Biotechnol 68, 42-45 (2005).
 +
* Jin, Y.S., Alper, H., Yang, Y.T. & Stephanopoulos, G. Improvement of xylose uptake and ethanol production in recombinant Saccharomyces cerevisiae through an inverse metabolic engineering approach. Appl Environ Microbiol 71, 8249-8256 (2005).
 +
* Alper, H., Jin, Y.S., Moxley, J.F. & Stephanopoulos, G. Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli. Metab Eng 7, 155-164 (2005).
 +
* Jin, Y.S., Laplaza, J.M. & Jeffries, T.W. Saccharomyces cerevisiae engineered for xylose metabolism exhibits a respiratory response. Appl Environ Microbiol 70, 6816-6825 (2004).
 +
* Jin, Y.S. & Jeffries, T.W. Stoichiometric network constraints on xylose metabolism by recombinant Saccharomyces cerevisiae. Metab Eng 6, 229-238 (2004).
 +
* Jeffries, T.W. & Jin, Y.S. Metabolic engineering for improved fermentation of pentoses by yeasts. Appl Microbiol Biotechnol 63, 495-509 (2004).
 +
* Jin, Y.S., Ni, H., Laplaza, J.M. & Jeffries, T.W. Optimal growth and ethanol production from xylose by recombinant Saccharomyces cerevisiae require moderate D-xylulokinase activity. Appl Environ Microbiol 69, 495-503 (2003).
 +
* Jin, Y.S. & Jeffries, T.W. Changing flux of xylose metabolites by altering expression of xylose reductase and xylitol dehydrogenase in recombinant Saccharomyces cerevisiae. Appl Biochem Biotechnol 105 -108, 277-286 (2003).
 +
* Jin, Y.S., Jones, S., Shi, N.Q. & Jeffries, T.W. Molecular cloning of XYL3 (D-xylulokinase) from Pichia stipitis and characterization of its physiological function. Appl Environ Microbiol 68, 1232-1239 (2002).
 +
* Jin, Y.S., Lee, T.H., Choi, Y.D., Ryu, Y.W. & Seo, J.H. Conversion of xylose to ethanol by recombinant Saccharomyces cerevisiae containing genes for xylose reductase and xylitol dehydrogenase from Pichia stipitis. J Microbiol Biotechnol 10, 564-567 (2000).
 +
* Jeffries, T.W. & Jin, Y.S. Ethanol and thermotolerance in the bioconversion of xylose by yeasts. Adv Appl Microbiol 47, 221-268 (2000).

Revision as of 18:32, 30 September 2013

Molecular and Systems Biotechnology Lab @ UIUC

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Contents

Peer-reviewed articles

2013

  • Kim, H.J., Lee, H.R., Kim, C.S., Jin, Y.S., Seo, J.H. Investigation of protein expression profiles of erythritol-producing Candida magnoliae in response to glucose perturbation. Enzyme and Microbial Technology Link
  • Kim, H.J., Turner, T.L., Jin, Y.S. Combinatorial genetic perturbation to refince metabolic circuits for producing biofuels and biochemicals. Biotechnology Advances (In press)
  • Kim, S.J., Seo, S.O., Jin, Y.S. & Seo, J.H. Production of 2,3-butanediol by engineered Saccharomyces cerevisiae. Bioresource Technology Link
  • Wang, Y., Li, X.Z., Milne, C., Janssen, H., Lin, W., Phan, G., Hu, H., Jin, Y.S., Price, N. & Blaschek, H. Development of a gene knockout system using mobile group II introns (Targetron) and genetic disruption of acid production pathways in Clostridium beijerinckii. Applied and Environmental Microbiology Link
  • Lee, W.H., Nan, H., Kim, H.J. & Jin, Y.S. Simultaneous saccharification and fermentation by engineered Saccharomyces cerevisiae without supplementing extracellular beta-glucosidase. Journal of Biotechnology Link
  • Kim, S.R., Park, Y.C., Jin, Y.S., & Seo, J.H. Strain engineering of Saccharomyces cerevisiae for enhanced xylose metabolism. Biotechnology Advances (accepted)
  • Wei, N., Xu, H., Kim, S.R., & Jin, Y.S. Deletion of FPS1 coding for aquaglyceroporin Fps1p improves xylose fermentation by engineered Saccharomyces cerevisiae. Applied and Environmental Microbiology Link
  • Kim, S.R., Kwee, N.R., Kim, H.J. & Jin, Y.S. Feasibility of xylose fermentation by engineered Saccharomyces cerevisiae overexpressing endogenous aldose reductase (GRE3), xylitol dehydrogenase (XYL2) and xylulokinase (XYL3) from Scheffersomyces stipitis. FEMS Yeast Research Link
  • Lee, W.H., Kim, M.D., Jin, Y.S. & Seo, J.H. Engineering of NADPH regenerators in Escherichia coli for enhanced biotransformation. Applied Microbiology and Biotechnology Link
  • Kim, S.R., Skerker, J.M., Kang, W., Lesmana, A., Wei, N., Arkin, A.P. & Jin, Y.S. Rational and evolutionary engineering approaches uncover a small set of genetic changes efficient for rapid xylose fermentation in Saccharomyces cerevisiae. PLOS One Link
  • Kim, S.R., Lee, K.S., Kong, I.K., Lesmana, A., Lee, W.H., Seo, J.H., Kweon, D.H. & Jin, Y.S. Construction of an efficient xylose-fermenting diploid Saccharomyces cerevisiae strain through mating of two engineered haploid strains capable of xylose assimilation. Journal of Biotechnology Link

2012

  • Guo, B., Zhang, Y., Yu, G., Lee, W.H., Jin, Y.S.& Morgenroth, E., Two-stage acidic-alkaline hydrothermal pretreatment of lignocellulose for the high recovery of cellulose and hemicellulose sugars. Applied Biochemistry and Biotechnology Link
  • Ha,S.J., Kim, H., Lin, Y., Jang, M.U., Galazka, J.M., Kim, T.J., Cate. J.H. & Jin, Y.S. Single amino acid substitutions of HXT2.4 from Scheffersomyces stipitis lead to improved cellobiose fermentation by engineered Saccharomyces cerevisiae. Applied and Environmental Microbiology Link
  • Ha, S.J., Galazka, J.M., Oh, E.J., Kordic, V., Kim, H., Jin, Y.S., & Cate, J.H. Energetic benefits and rapid cellobiose fermentation by Saccharomyces cerevisiae expressing cellobiose phosphorylase and mutant cellodextrin transporters. Metabolic Engineering Link
  • Wei, N. Quarterman, J., & Jin, Y.S. Marine macroalgae: an untapped resource for producing fuels and chemicals. Trends in Biotechnol. Link
  • Oh, E.J., Ha, S.J., Kim, S.R., Lee, W.H., Galazka, J.M., Cate, J.H. & Jin, Y.S. Enhanced xylitol production through simultaneous co-utilization of cellobiose and xylose by engineered Saccharomyces cerevisiae. Metabolic Engineering Link
  • Lee, K.S., Kim, J.S., Heo, P., Yang, T.J., Sung, Y.J., Cheon, Y., Koo, H.M., Yu, B.J., Seo, J.H., Jin, Y.S., Park, J.C., Kweon, D.H. Characterization of Saccharomyces cerevisiae promoters for heterologous gene expression in Kluyveromyces marxianus. Appl Microbiol Biotechnol Link
  • Lee, W.H., Pathanibul, P., Quarterman, J., Jo, J.H., Han, N.S., Miller, M.J., Jin, Y.S.& Seo, J.H. Whole cell biosynthesis of a functional oligosaccharide, 2-fucosyllactose, using engineered Escherichia coli. Microbial Cell Factories 11, 48 Link
  • Lee, W.H., Seo, S.O., Bae, Y.H., Nan, H., Jin, Y.S.& Seo, J.H. Isobutanol production in engineered Saccharomyces cerevisiae by overexpression of 2-ketoisovalerate decarboxylase and valine biosynthetic enzymes. Bioprocess and Biosystems Engineering 35, 1467-75 Link
  • Kim, S.R., Ha, S.J., Kong, I.I., & Jin, Y.S. High expression of XYL2 coding for xylitol dehydrogenase is necessary for efficient xylose fermentation by engineered Saccharomyces cerevisiae Metab. Eng. 14, 336-343 Link
  • Guo, B., Zhang, Y., Ha, S. J., Jin, Y.S.& Morgenroth, E. Combined biomimetic and inorganic acids hydrolysis of hemicellulose in Miscanthus for bioethanol production. Bioresource Technol 110,278-87 Link
  • Kim, S.R., Ha, S.J., Wei, N., Oh, E.J., & Jin, Y.S. Simultaneous co-fermenation of mixed sugars: a promising strategy for producing cellulosic ethnaol. Trend Biotechnol 30,274–282 Link
  • Jin, Y.S. & Cate, J.H. Model-guided strain improvement: Simultaneous hydrolysis and co-fermentation of cellulosic sugars. Biotechnol. J. 7,361-73. Link
  • Cha, C., Kim, S.R., Jin, Y.S. & Kong, H.J. Tuning structural durability of yeast-encapsulating alginate gel beads with interpenetrating networks for sustained bioethanol production. Biotechnol. Bioeng. 109,63-73 Link

2011

  • Lu, C.H., Choi, J.H., Engelmann Moran, N., Jin, Y.S. & Erdman, J. Laboratory-scale production of 13C-labeled lycopene and phytoene by bioengineered Escherichia. J Agric Food Chem Link
  • Kim, J.S., Heo P., Yang. T.J., Lee, K.S., Jin Y.S., Kim, S. K., Shin, D. & Kweon, D.H. Bacterial persisters tolerate antibiotics by not producing hydroxyl radicals. Biochem. Biophys. Res. Commun. Link
  • Milne, C.B., Eddy, J.A., Raju, R., Ardekani,S., Kim, P.J., Senger, R. S., Jin, Y.S., Blaschek, H.P. & Price, N.D. Metabolic network reconstruction and genome-scale model of butanol-producing strain Clostridium beijerinckii NCIMB 8052 BMC Systems Biology 5:130. Link
  • Ha, S.J., Wei, Q., Kim, S.R., Galazka, J., Cate, J.H. & Jin, Y.S. Co-fermentation of cellobiose and galactose by an engineered Saccharomyces cerevisiae. Appl. Environ. Microbiol. 77, 5822-5826. Link, Related News
  • Ha, S.J., Kim, S.R., Choi J.H., Park, M.S. & Jin Y.S. Xylitol does not inhibit xylose fermentation by engineered Saccharomyces cerevisiae expressing xylA as severely as it inhibits xylose isomerase reaction in vitro. Appl Microbiol Biotechnol (in press) Link
  • Ha, S.J., Galazka J.M., Rin Kim S., Choi J.H., Yang X., Seo J.H., Louise Glass N., Cate J.H., & Jin Y.S.Engineered Saccharomyces cerevisiae capable of simultaneous cellobiose and xylose fermentation. Proc Natl Acad Sci U S A. 108, 504-509 (2011) Link, PDF,Supporting Information, In This Issue-PNAS, Related News
  • Lee, K.S., Hong, M.E., Jung, S.C., Ha, S.J., Yu, B.J., Koo, H.M., Park, S.M., Seo, J.H., Kweon, D.H., Park, J.C. & Jin, Y.S. Improved galactose fermentation of Saccharomyces cerevisiae through inverse metabolic engineering. Biotechnol Bioeng. 108, 621-632. Link

2010

  • Kim, S.R., Lee, K.S., Choi, J.H., Ha, S.J., Kweon, D.H., Seo, J.H. & Jin, Y.S. Repeated-batch fermentations of xylose and glucose-xylose mixtures using a respiration-deficient Saccharomyces cerevisiae engineered for xylose metabolism. J Biotechnol 150, 404-407 (2010). Link
  • Jung, S.C., Smith, C.L., Lee, K.S., Hong, M.E., Kweon, D.H., Stephanopoulos, G. & Jin, Y.S. Restoration of growth phenotypes of Escherichia coli DH5alpha in minimal media through reversal of a point mutation in purB. Appl Environ Microbiol 76, 6307-6309 (2010). Link, Related News1, Related News2
  • Hong, M.E., Lee, K.S., Yu, B.J., Sung, Y.J., Park, S.M., Koo, H.M., Kweon, D.H., Park, J.C. & Jin, Y.S. Identification of gene targets eliciting improved alcohol tolerance in Saccharomyces cerevisiae through inverse metabolic engineering. J Biotechnol 149, 52-59 (2010). Link, Related News

2009

  • Tyo, K.E., Jin, Y.S., Espinoza, F.A. & Stephanopoulos, G. Identification of gene disruptions for increased poly-3-hydroxybutyrate accumulation in Synechocystis PCC 6803. Biotechnol Prog 25, 1236-1243 (2009). Link
  • Shin, J.Y., Shin, J.I., Kim, J.S., Yang, Y.S., Hwang, Y., Yang, J.S., Shin, D., Seo, J.H., Jin, Y.S., Park, Y.C., Hwang, J.S. & Kweon, D.H. Assembly of Coenzyme Q10 nanostructure resembling nascent discoidal high density lipoprotein particle. Biochem Biophys Res Commun 388, 217-221 (2009).
  • Lee, K., Shin, J.Y., Yang, Y.S., Shin, J.I., Park, Y.C., Seo, J.H., Park, T.H., Shin, C.S., Jin, Y.S. & Kweon, D.H. Towards a microarray of functional membrane proteins: Assembly of a surface-attachable, membrane-protein-anchored membrane structure using apolipoprotein A-1. Enz. Microb Tech 44, 217-222 (2009).
  • Lee, J., Seo, E., Kweon, D.H., Park, K. & Jin, Y.S. Fermentation of rice bran and defatted rice rran for butanol production using Clostridium beijerinckii NCIMB 8052. J. Microbiol. Biotechnol. 19, 482-490 (2009).

2008

  • Lee, K.S., Chang, E.H., Shin, J.Y., Kweon, D.H., Park, K.M. & Jin, Y.S. Production of casein phosphopeptides using Streptococcus faecalis var. liquefaciens cell immobilization. Korean J Biotechnol Bioeng 23, 59-64 (2008).
  • Jung, C.H., Yang, Y.S., Kim, J.S., Shin, J.I., Jin, Y.S., Shin, J.Y., Lee, J.H., Chung, K.M., Hwang, J.S., Oh, J.M., Shin, Y.K. & Kweon, D.H. A search for synthetic peptides that inhibit soluble N-ethylmaleimide sensitive-factor attachment receptor-mediated membrane fusion. FEBS J 275, 3051-3063 (2008).

2006-2007

  • Jung, S.C., Chung, C.Y., Kim, J.S., Kweon, D.H., Park, K.M. & Jin, Y.S. Policosanol production from rice bran oil byproducts. Food Eng Prog 11, 293-297 (2007)
  • Jin, Y.S. & Stephanopoulos, G. Multi-dimensional gene target search for improving lycopene biosynthesis in Escherichia coli. Metab Eng 9, 337-347 (2007).
  • Jeffries, T.W., Grigoriev, I.V., Grimwood, J., Laplaza, J.M., Aerts, A., Salamov, A., Schmutz, J., Lindquist, E., Dehal, P., Shapiro, H., Jin, Y.S., Passoth, V. & Richardson, P.M. Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis. Nat Biotechnol 25, 319-326 (2007).
  • Laplaza, J.M., Torres, B.R., Jin, Y.S. & Jeffries, T.W. Sh ble and Cre adapted for functional genomics and metabolic engineering of Pichia stipitis. Enz Microb Tech 38, 741-747 (2006).
  • Jin, Y.S., Cruz, J. & Jeffries, T.W. Xylitol production by a Pichia stipitis D-xylulokinase mutant. Appl Microbiol Biotechnol 68, 42-45 (2005).
  • Jin, Y.S., Alper, H., Yang, Y.T. & Stephanopoulos, G. Improvement of xylose uptake and ethanol production in recombinant Saccharomyces cerevisiae through an inverse metabolic engineering approach. Appl Environ Microbiol 71, 8249-8256 (2005).
  • Alper, H., Jin, Y.S., Moxley, J.F. & Stephanopoulos, G. Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli. Metab Eng 7, 155-164 (2005).
  • Jin, Y.S., Laplaza, J.M. & Jeffries, T.W. Saccharomyces cerevisiae engineered for xylose metabolism exhibits a respiratory response. Appl Environ Microbiol 70, 6816-6825 (2004).
  • Jin, Y.S. & Jeffries, T.W. Stoichiometric network constraints on xylose metabolism by recombinant Saccharomyces cerevisiae. Metab Eng 6, 229-238 (2004).
  • Jeffries, T.W. & Jin, Y.S. Metabolic engineering for improved fermentation of pentoses by yeasts. Appl Microbiol Biotechnol 63, 495-509 (2004).
  • Jin, Y.S., Ni, H., Laplaza, J.M. & Jeffries, T.W. Optimal growth and ethanol production from xylose by recombinant Saccharomyces cerevisiae require moderate D-xylulokinase activity. Appl Environ Microbiol 69, 495-503 (2003).
  • Jin, Y.S. & Jeffries, T.W. Changing flux of xylose metabolites by altering expression of xylose reductase and xylitol dehydrogenase in recombinant Saccharomyces cerevisiae. Appl Biochem Biotechnol 105 -108, 277-286 (2003).
  • Jin, Y.S., Jones, S., Shi, N.Q. & Jeffries, T.W. Molecular cloning of XYL3 (D-xylulokinase) from Pichia stipitis and characterization of its physiological function. Appl Environ Microbiol 68, 1232-1239 (2002).
  • Jin, Y.S., Lee, T.H., Choi, Y.D., Ryu, Y.W. & Seo, J.H. Conversion of xylose to ethanol by recombinant Saccharomyces cerevisiae containing genes for xylose reductase and xylitol dehydrogenase from Pichia stipitis. J Microbiol Biotechnol 10, 564-567 (2000).
  • Jeffries, T.W. & Jin, Y.S. Ethanol and thermotolerance in the bioconversion of xylose by yeasts. Adv Appl Microbiol 47, 221-268 (2000).
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