Josh Michener

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==Lab history==
==Lab history==
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*Postdoc in the Marx Lab, Harvard Department of Organismic and Evolutionary Biology
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*NRSA Postdoctoral Fellow in the Marx Lab, Harvard Department of Organismic and Evolutionary Biology
*Graduate student in the Smolke Lab, Caltech/Stanford Bioengineering. Collaborated with Frances Arnold (Caltech ChemE) and Jens Nielsen (Chalmers Systems Bio)
*Graduate student in the Smolke Lab, Caltech/Stanford Bioengineering. Collaborated with Frances Arnold (Caltech ChemE) and Jens Nielsen (Chalmers Systems Bio)
*UROP in the Endy Lab at MIT
*UROP in the Endy Lab at MIT

Revision as of 12:59, 25 March 2013

Josh Michener

Education

  • PhD, 2012, Bioengineering at Caltech
  • S.B. 2006, Chemical Engineering and Biology at MIT

Lab history

  • NRSA Postdoctoral Fellow in the Marx Lab, Harvard Department of Organismic and Evolutionary Biology
  • Graduate student in the Smolke Lab, Caltech/Stanford Bioengineering. Collaborated with Frances Arnold (Caltech ChemE) and Jens Nielsen (Chalmers Systems Bio)
  • UROP in the Endy Lab at MIT

Contact Info

Josh Michener
16 Divinity Ave Room 3082
Cambridge, MA, 02138

Image:Michener-email.png

Research

My research focuses on the combination of rational and evolutionary methods to build, analyze, and optimize metabolic pathways.

Publications

  • Michener JK, Nielsen J, and Smolke CD. Identification and Treatment of Heme Depletion due to Over-expression of a Lineage of Evolved P450 Monooxygenases. PNAS. 2012; 109 (47) 19504-19509. [1]
  • Michener JK and Smolke CD. High-throughput enzyme evolution in Saccharomyces cerevisiae using a synthetic RNA switch. Metab Eng. 2012 Jul; 14(4):306-16. [2]
  • Michener JK, Thodey K, Liang JC, Smolke CD. Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways. Metab Eng. 2012 May; 14(3):212-22. [3]
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