Josh Michener

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==Contact Info==
==Contact Info==
Josh Michener<br>
Josh Michener<br>
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Bioengineering - Smolke Lab<br>
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16 Divinity Ave Room 3082<br>
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Y2E2-B07, MC 4200<br>
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Cambridge, MA, 02138<br>
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473 Via Ortega<br>
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Stanford, CA 94305<br>
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[[Image:Michener-email.png]]
[[Image:Michener-email.png]]
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==Publications==
==Publications==
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*'''Michener JK'', Nielsen J, and Smolke CD. Identification and Treatment of Heme Depletion due to Over-expression of a Lineage of Evolved P450 Monooxygenases. PNAS. ''In Press''
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*'''Michener JK''', Nielsen J, and Smolke CD. Identification and Treatment of Heme Depletion due to Over-expression of a Lineage of Evolved P450 Monooxygenases. PNAS. ''In Press''
*'''Michener JK''' and Smolke CD. High-throughput enzyme evolution in ''Saccharomyces cerevisiae'' using a synthetic RNA switch. Metab Eng. 2012 Jul;14(4):306-16. [http://www.sciencedirect.com/science/article/pii/S109671761200047X]
*'''Michener JK''' and Smolke CD. High-throughput enzyme evolution in ''Saccharomyces cerevisiae'' using a synthetic RNA switch. Metab Eng. 2012 Jul;14(4):306-16. [http://www.sciencedirect.com/science/article/pii/S109671761200047X]
*'''Michener JK''', Thodey K, Liang JC, Smolke CD. Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways. Metab Eng. 2012 May;14(3):212-22. [http://www.sciencedirect.com/science/article/pii/S1096717611000942]
*'''Michener JK''', Thodey K, Liang JC, Smolke CD. Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways. Metab Eng. 2012 May;14(3):212-22. [http://www.sciencedirect.com/science/article/pii/S1096717611000942]

Revision as of 20:29, 9 October 2012

Josh Michener

Education

  • PhD, 2012, Bioengineering at Caltech
  • S.B. 2006, Chemical Engineering and Biology at MIT

Lab history

  • Postdoc in the Marx Lab, Harvard Department of Organismic and Evolutionary Biology
  • Graduate student in the Smolke Lab, Caltech/Stanford Bioengineering. Collaborated with Frances Arnold (Caltech ChemE) and Jens Nielsen (Chalmers Systems Bio)
  • UROP in the Endy Lab at MIT

Contact Info

Josh Michener
16 Divinity Ave Room 3082
Cambridge, MA, 02138

Image:Michener-email.png

Research

My research focuses on the combination of rational and evolutionary methods to build, analyze, and optimize metabolic pathways.

Publications

  • Michener JK, Nielsen J, and Smolke CD. Identification and Treatment of Heme Depletion due to Over-expression of a Lineage of Evolved P450 Monooxygenases. PNAS. In Press
  • Michener JK and Smolke CD. High-throughput enzyme evolution in Saccharomyces cerevisiae using a synthetic RNA switch. Metab Eng. 2012 Jul;14(4):306-16. [1]
  • Michener JK, Thodey K, Liang JC, Smolke CD. Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways. Metab Eng. 2012 May;14(3):212-22. [2]
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