KP Ramirez Week 3

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What do i know about the HIV virus?

In Class Activity

  • I know that HIV is a precursor to AIDS which is an immune disorder. It's transferred through blood and seminal fluids and considered a global pandemic. Aside from this very basic information there isn't much more that I know directly about the virus. I am unsure if there are variations in strains of HIV, as well as the difference between those who have been living with the virus for many years, versus those who only lasted a brief period of time.

Questions

  • Has there been any major developments in finding a cure for HIV?
  • How do some individuals living with HIV delay the onset of AIDS?
  • How many strains of HIV are there?


Assignment

I worked through the Bioinformatics for dummies book and immediately noticed several differences. The book itself begins with a brief introduction to the PubMED database including how to begin a query. The screen shots featured in the book were out of date, this is common as one aspect of Bioinformatics is the constantly evolving interface of databases. Secondly I ran through the sample queries it asks in the book, namely the search of the name Abergel and dUTPase together. In the book it cites that this will provide only one result which would in turn present the full abstract right away, however, since the publication there now yields two results.

Searches

I began searching PubMed and used the keywords Human Immunodeficiency Virus Type 1, after looking through the results I decided on the following paper after reading through the abstract[1]. It's important to note that the full text for the following article was not available from PubMed directly, instead I was able to access the full text through Google Scholar in the following link. [2]

Comparisons

I felt that there were many ways to approach my comparisons between the databases. The first, as cited earlier was that PubMed did not have the full text available for the article I chose, however, this was available through Google Scholar and Web of Knowledge. Google Scholar was extremely easy to use as the article was found through the key words Human Immunodeficiency Virus Type 1 and additionally could be accessed by typing the name of the entire article. Web of Knowledge had a different query, extremely similar to literature databases, where you can type in Author searchs, Key words, and other through many search bars. While this gives the ability to be more comprehensive, it is not as user friendly as the queries from PubMed or Google Scholar. In order to best compare my results I used the same key word search (Human Immunodeficiency Virus Type 1)for Google Scholar and the ISI Web of ScienceThe following were the top ten results for each.

PubMed

In Class Assignment

Journal Assignments

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Links

BIOL398-01/S10:Week 2