Kafatos:Meister, Stephan: Difference between revisions
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== Research Interests == | <!---------------------------------------------------EDUCATION---------------------------------------------------> | ||
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===Education=== | |||
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* ''2007-present'' Postdoctoral Fellow at the [http://www.scripps.edu Scripps Research Institute], San Diego, USA | |||
* ''2005-2006'' working at [http://www3.imperial.ac.uk/ Imperial College], London, UK. | |||
* ''2001-2006'' PhD student, [http://www.embl.de/ EMBL], Heidelberg, Germany. | |||
* ''1999-2000'' visiting graduate student at [http://www.duke.edu/ Duke University], NC, USA. | |||
* ''1996-2001'' Diplom Biol., [http://www.uni-wuerzburg.de/ University of Wuerzburg], Germany. | |||
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<!---------------------------------------------------RESEARCH INTERESTS---------------------------------------------------> | |||
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===Research Interests=== | |||
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====The role of PGRP proteins in innate immunity pathways in the malaria vector ''Anopheles gambiae''.==== | ====The role of PGRP proteins in innate immunity pathways in the malaria vector ''Anopheles gambiae''.==== | ||
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The ''Anopheles gambiae'' peptidoglycan recognition protein (PGRP) gene family consists of 7 genes with 13 PGRP domains. We analyze the role of these genes in the mosquito immune defense to bacteria and the malaria parasite ''Plasmodium berghei''. We have previously shown that the NF-κB transcription factor REL2 is involved in defense against both types of bacteria and malaria parasites <cite>meister2005</cite>. IMD is only responsible for the reaction against Gram-positive bacteria and ''Plasmodium''. Our data suggests significant divergence as well as many similarities of immune signaling between ''Anopheles gambiae'' and the fruit fly ''Drosophila melanogaster''. The differences most likely reflect the different lifestyles of the two insects and, consequently, different infectious agents that the two insects encounter during their lifetimes. In mosquitoes, one of these agents is the malaria parasite ''Plasmodium''. <br><br> | The ''Anopheles gambiae'' peptidoglycan recognition protein (PGRP) gene family consists of 7 genes with 13 PGRP domains. We analyze the role of these genes in the mosquito immune defense to bacteria and the malaria parasite ''Plasmodium berghei''. We have previously shown that the NF-κB transcription factor REL2 is involved in defense against both types of bacteria and malaria parasites <cite>meister2005</cite>. IMD is only responsible for the reaction against Gram-positive bacteria and ''Plasmodium''. Our data suggests significant divergence as well as many similarities of immune signaling between ''Anopheles gambiae'' and the fruit fly ''Drosophila melanogaster''. The differences most likely reflect the different lifestyles of the two insects and, consequently, different infectious agents that the two insects encounter during their lifetimes. In mosquitoes, one of these agents is the malaria parasite ''Plasmodium''. <br><br> | ||
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== | <!---------------------------------------------------POSTERS---------------------------------------------------> | ||
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===Conference posters=== | |||
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[[Image:BioMalPar_Poster.png|thumb|left|220px|BioMalPar Conference, Heidelberg, Germany, 2006]] | |||
[[Image:BDV_Course_2004.png|thumb|left|230px|BDV Course, Colorado, USA 2004]] | |||
[[Image:Trest_2003.png|thumb|left|110px|EMBO PRR Workshop, Trest by Prague 2003]] | |||
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== Publications == | {|cellspacing="5" cellpadding="10" style="background:#ffffff; width: 800px;" | ||
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===Publications=== | |||
---- | |||
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<biblio> | <biblio> | ||
#phd2006 Meister S, ''PhD Thesis'', EMBL/University of Heidelberg, 2006. | #phd2006 Meister S, ''[http://www.ub.uni-heidelberg.de/archiv/6571/ PhD Thesis]'', EMBL/University of Heidelberg, 2006. | ||
#meister2005 pmid=16076953 | #meister2005 pmid=16076953 | ||
#meister2004 pmid=15582524 | #meister2004 pmid=15582524 | ||
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#Diplom Meister S, ''Diploma Thesis'', University of Wuerzburg, 2001. | #Diplom Meister S, ''Diploma Thesis'', University of Wuerzburg, 2001. | ||
</biblio> | </biblio> | ||
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Latest revision as of 12:21, 13 November 2007
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Stephan Meister
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Education
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Research Interests
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Conference posters |