Kafatos:Meister, Stephan: Difference between revisions
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<font size="3">[http://www.embl.de/training/phdprogramme/index.html EMBL PhD] student at [http://www.imperial.ac.uk/ Imperial College] in the [[kafatos:Kafatos/Christophides Lab|Kafatos/Christophides Lab]].</font | <font size="3">[http://www.embl.de/training/phdprogramme/index.html EMBL PhD] student at [http://www.imperial.ac.uk/ Imperial College] in the [[kafatos:Kafatos/Christophides Lab|Kafatos/Christophides Lab]].</font> | ||
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===Education=== | |||
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* 2001-present, PhD student, [http://www.embl.de/ EMBL], Heidelberg, Germany. | |||
* 1999-2000 visiting graduate student at [http://www.duke.edu/ Duke University], NC, USA. | |||
* 1996-2001, Diplom Biol., [http://www.uni-wuerzburg.de/ University of Wuerzburg], Germany. | |||
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== Research Interests == | |||
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===Research Interests=== | |||
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====The role of PGRP proteins in innate immunity pathways in the malaria vector ''Anopheles gambiae''.==== | ====The role of PGRP proteins in innate immunity pathways in the malaria vector ''Anopheles gambiae''.==== | ||
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The ''Anopheles gambiae'' peptidoglycan recognition protein (PGRP) gene family consists of 7 genes with 13 PGRP domains. We analyze the role of these genes in the mosquito immune defense to bacteria and the malaria parasite ''Plasmodium berghei''. We have previously shown that the NF-κB transcription factor REL2 is involved in defense against both types of bacteria and malaria parasites <cite>meister2005</cite>. IMD is only responsible for the reaction against Gram-positive bacteria and ''Plasmodium''. Our data suggests significant divergence as well as many similarities of immune signaling between ''Anopheles gambiae'' and the fruit fly ''Drosophila melanogaster''. The differences most likely reflect the different lifestyles of the two insects and, consequently, different infectious agents that the two insects encounter during their lifetimes. In mosquitoes, one of these agents is the malaria parasite ''Plasmodium''. <br><br> | The ''Anopheles gambiae'' peptidoglycan recognition protein (PGRP) gene family consists of 7 genes with 13 PGRP domains. We analyze the role of these genes in the mosquito immune defense to bacteria and the malaria parasite ''Plasmodium berghei''. We have previously shown that the NF-κB transcription factor REL2 is involved in defense against both types of bacteria and malaria parasites <cite>meister2005</cite>. IMD is only responsible for the reaction against Gram-positive bacteria and ''Plasmodium''. Our data suggests significant divergence as well as many similarities of immune signaling between ''Anopheles gambiae'' and the fruit fly ''Drosophila melanogaster''. The differences most likely reflect the different lifestyles of the two insects and, consequently, different infectious agents that the two insects encounter during their lifetimes. In mosquitoes, one of these agents is the malaria parasite ''Plasmodium''. <br><br> | ||
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==Publications== | <!---------------------------------------------------PUBLICATIONS---------------------------------------------------> | ||
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===Publications=== | |||
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===Conference posters=== | |||
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[[Image:BioMalPar_Poster.png|thumb|left|220px|BioMalPar Conference, Heidelberg, Germany, 2006]] | |||
[[Image:BDV_Course_2004.png|thumb|left|230px|BDV Course, Colorado, USA 2004]] | |||
[[Image:Trest_2003.png|thumb|left|110px|EMBO PRR Workshop, Trest by Prague 2003]] | |||
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Revision as of 03:36, 24 August 2006
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Stephan Meister
Laboratory of Insect Immunogenomics fourth floor, desk 483
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EMBL PhD student at Imperial College in the Kafatos/Christophides Lab.
Education
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Research Interests
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Conference posters |