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| <font size="4">Dina Vlachou</font size> | | <font size="4">Dina Vlachou</font size> |
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| <font size="2">Division of Cell & Molecular Biology<br> | | <font size="2"> |
| South Kensington Campus, SAF<br> | | Division of Cell and Molecular Biology<br> |
| London, SW72AZ<br> | | Faculty of Natural Sciences<br> |
| UK<br>
| | Imperial College London<br> |
| <br><br> | | Sir Alexander Fleming Building<br> |
| ''d.vlachou[at]imperial.ac.uk'' | | South Kensington Campus<br> |
| | SW7 2AZ<br> |
| | London<br> |
| | United Kingdom<br><br> |
| | Tel.: +44 20 759 42031<br> |
| | Fax: +44 20 759 41759<br> |
| | Email: '''d.vlachou@imperial.ac.uk''' |
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| </font size> | | </font size> |
| |} | | |} |
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| Senior Research Associate at [http://www.imperial.ac.uk/ Imperial College], London<br>.
| | '''Research Fellow''' at [http://www.imperial.ac.uk/people/d.vlachou Imperial College], London<br>. |
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| == Education==
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| '''1990: Diploma''' in Biology, University of Thessaloniki, Greece<br>
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| '''1997: Ph.D.''' in Molecular Biology and Evolution, University of Athens, Greece<br>
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| ==Professional profile==
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| '''1990-1991: '''Research assistant, Division of Genetic and Biotechnology, Department of Biology, University of Athens, Greece.
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| Postgraduate research in insect molecular biology.<br>
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| '''1991-1997: '''PhD studies, Division of Genetic and Biotechnology, Department of Biology, University of Athens, Greece.
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| Research Area: Functional and evolutionary analysis of chorion genes in Diptera.<br>
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| '''1997-2000: '''Post-doctoral fellow, Institute of Molecular Biology and Biotechnology/Foundation for Research and Technology (IMBB/FORTH), Crete, Greece.
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| Research Area: Identification of Anopheles gambiae midgut proteins putatively interacting with Plasmodium surface proteins.<br>
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| '''2000-2001: '''RTN Post-doctoral fellow, Department of Parasitology, University of Leiden (LUMC), Leiden, The Netherlands.
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| Research Area: Genetic manipulation of Plasmodium berghei and development of alternative tools for conditional knockout and transient expression of genes in the parasite mosquito stages.<br>
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| '''2001-2003: '''Marie Curie Research Fellow, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
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| Research Area: Molecular and cellular dissection of mosquito midgut invasion, and mosquito immune responses.<br>
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| '''2003-2005: '''Senior Research Associate, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
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| Research Area: Molecular and cellular dissection of mosquito midgut invasion, and mosquito immune responses.<br>
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| '''2005-present:''' Senior Research Scientist, Division of Cell and Molecular Biology, Imperial College London, United Kingdom.
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| Research Area: Functional genomics of mosquito/parasite interactions.<br>
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| == Research Interests ==
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| My scientific interests lie in the field of infectious diseases, especially insect-borne. Malaria is a leading parasitic disease transmitted by ''Anopheles'' mosquitoes. It affects half of the global population and kills 1-3 million people every year, the vast majority children aged below 5 in sub-Saharan Africa. My research focuses on the understanding of molecular and cellular interactions between ''Anopheles'' mosquitoes and malaria parasites, ''Plasmodium'', using functional genomics and emphasizing on mosquito midgut infection, the most critical stage in the malaria transmission cycle. It utilizes both laboratory model transmission systems, i.e. Anopheles mosquitoes and rodent parasites ''Plasmodium berghei'', and naturally interacting populations of ''Anopheles gambiae'' and human parasites ''Plasmodium falciparum''. Detail understanding of parasite/mosquito interactions may guide development of novel control strategies to control the disease.<br><br>
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| '''Current research projects:'''<br>
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| '''• '''Functional genomic dissection of the Anopheles gambiae tissue responses to Plasmodium developmental stages<br>
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| '''• '''Comparative genomic analysis of the mosquito responses to the rodent parasite Plasmodium berghei and the human parasite Plasmodium falciparum in natural transmission conditions in Africa <br>
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| '''• '''Molecular and cell biological analysis of Plasmodium migration through the mosquito midgut <br>
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| '''• '''Monitoring of the sporogonic developmental transcriptome of Plasmodium berghei and its interaction with the mosquito transcriptome<br>
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| == Distinctions and Awards ==
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| • PhD individual fellowship by Academy of Athens, Greece (1993-1996) <br>
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| • Marie-Curie Individual Research Fellowship, European Commission, Fifth Framework Program (2001-2003)<br>
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| == Academic profile==
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| '''• '''Teaching assistantship of pre-graduated students at the Departments of Biology and Pharmacology, University of Athens, Greece (1991-1996)<br>
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| '''• '''Invited lecturer at postgraduate student course in Bioinformatics, University of Athens, Greece (May 2005)<br>
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| '''• '''Invited lecturer at 17th International Annual Biology of Disease Vectors Course (BDV), University of Liverpool, Liverpool, UK (16-28 July 2006)<br>
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| '''• '''Project leader and Thesis supervisor of Imperial College PhD candidates Timm Schlegelmilch, Ellen Bushell and Karolina Akinosoglou<br>
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| '''• '''Project leader and Thesis supervisor of BioMalPar International PhD Programme fellow Antonio Mendes<br>
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| '''• '''Thesis advisor of PhD candidate Caroline Harris (University of Montpellier, France)<br>
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| '''• '''Supervisor of final year project of Imperial College pre-graduate students (2007)<br>
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| '''• '''Examiner of final year project vivas of Imperial College pre-graduate students (2006, 2007)<br>
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| ==[http://www3.imperial.ac.uk/portal/page?_pageid=61,491607&_dad=portallive&_schema=PORTALLIVE&_pageid=61,491607 Publications]==
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| <biblio>
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| #waterhouse2007 pmid=17588928
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| #vlachou2006 pmid=16793259
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| #vlachou2005 pmid=16005290
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| #vlachou2005b pmid=15996894
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| #osta2004 pmid=15201288
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| #christophides2004 pmid=15199960
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| #vlachou2004 pmid=15186403
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| #dessens2003 pmid=12828632
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| #christophides2002 pmid=12364793
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| #vlachou2001 pmid=11404001
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| #vlachou2001b pmid=11223130
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| #margos2000 pmid=11163454
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| #sinden-kiamos pmid=10984433
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| #vlachou1997 pmid=9409839
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| </biblio>
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