Kafatos:Vlachou, Dina
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Dina Vlachou
Division of Cell and Molecular Biology
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Research Fellow at Imperial College, London
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Publications
- Bushell ES, Ecker A, Schlegelmilch T, Goulding D, Dougan G, Sinden RE, Christophides GK, Kafatos FC, and Vlachou D. Paternal effect of the nuclear formin-like protein MISFIT on Plasmodium development in the mosquito vector. PLoS Pathog. 2009 Aug;5(8):e1000539. DOI:10.1371/journal.ppat.1000539 |
- Baum J, Papenfuss AT, Mair GR, Janse CJ, Vlachou D, Waters AP, Cowman AF, Crabb BS, and de Koning-Ward TF. Molecular genetics and comparative genomics reveal RNAi is not functional in malaria parasites. Nucleic Acids Res. 2009 Jun;37(11):3788-98. DOI:10.1093/nar/gkp239 |
- Mendes AM, Schlegelmilch T, Cohuet A, Awono-Ambene P, De Iorio M, Fontenille D, Morlais I, Christophides GK, Kafatos FC, and Vlachou D. Conserved mosquito/parasite interactions affect development of Plasmodium falciparum in Africa. PLoS Pathog. 2008 May 16;4(5):e1000069. DOI:10.1371/journal.ppat.1000069 |
- Waterhouse RM, Kriventseva EV, Meister S, Xi Z, Alvarez KS, Bartholomay LC, Barillas-Mury C, Bian G, Blandin S, Christensen BM, Dong Y, Jiang H, Kanost MR, Koutsos AC, Levashina EA, Li J, Ligoxygakis P, Maccallum RM, Mayhew GF, Mendes A, Michel K, Osta MA, Paskewitz S, Shin SW, Vlachou D, Wang L, Wei W, Zheng L, Zou Z, Severson DW, Raikhel AS, Kafatos FC, Dimopoulos G, Zdobnov EM, and Christophides GK. Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes. Science. 2007 Jun 22;316(5832):1738-43. DOI:10.1126/science.1139862 |
- Vlachou D, Schlegelmilch T, Runn E, Mendes A, and Kafatos FC. The developmental migration of Plasmodium in mosquitoes. Curr Opin Genet Dev. 2006 Aug;16(4):384-91. DOI:10.1016/j.gde.2006.06.012 |
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Christophides G, Meister S, Koutsos A, et al, Systems biology of the Anopheles gainbiae innate immunity [MIM-GC-22590], ACTA TROP, 2005, Vol:95, Pages:S44-S45, ISSN:0001-706X
- Vlachou D, Schlegelmilch T, Christophides GK, and Kafatos FC. Functional genomic analysis of midgut epithelial responses in Anopheles during Plasmodium invasion. Curr Biol. 2005 Jul 12;15(13):1185-95. DOI:10.1016/j.cub.2005.06.044 |
- Vlachou D and Kafatos FC. The complex interplay between mosquito positive and negative regulators of Plasmodium development. Curr Opin Microbiol. 2005 Aug;8(4):415-21. DOI:10.1016/j.mib.2005.06.013 |
- Osta MA, Christophides GK, Vlachou D, and Kafatos FC. Innate immunity in the malaria vector Anopheles gambiae: comparative and functional genomics. J Exp Biol. 2004 Jul;207(Pt 15):2551-63. DOI:10.1242/jeb.01066 |
- Christophides GK, Vlachou D, and Kafatos FC. Comparative and functional genomics of the innate immune system in the malaria vector Anopheles gambiae. Immunol Rev. 2004 Apr;198:127-48. DOI:10.1111/j.0105-2896.2004.0127.x |
- Vlachou D, Zimmermann T, Cantera R, Janse CJ, Waters AP, and Kafatos FC. Real-time, in vivo analysis of malaria ookinete locomotion and mosquito midgut invasion. Cell Microbiol. 2004 Jul;6(7):671-85. DOI:10.1111/j.1462-5822.2004.00394.x |
- Dessens JT, Sidén-Kiamos I, Mendoza J, Mahairaki V, Khater E, Vlachou D, Xu XJ, Kafatos FC, Louis C, Dimopoulos G, and Sinden RE. SOAP, a novel malaria ookinete protein involved in mosquito midgut invasion and oocyst development. Mol Microbiol. 2003 Jul;49(2):319-29. DOI:10.1046/j.1365-2958.2003.03566.x |
- Christophides GK, Zdobnov E, Barillas-Mury C, Birney E, Blandin S, Blass C, Brey PT, Collins FH, Danielli A, Dimopoulos G, Hetru C, Hoa NT, Hoffmann JA, Kanzok SM, Letunic I, Levashina EA, Loukeris TG, Lycett G, Meister S, Michel K, Moita LF, Müller HM, Osta MA, Paskewitz SM, Reichhart JM, Rzhetsky A, Troxler L, Vernick KD, Vlachou D, Volz J, von Mering C, Xu J, Zheng L, Bork P, and Kafatos FC. Immunity-related genes and gene families in Anopheles gambiae. Science. 2002 Oct 4;298(5591):159-65. DOI:10.1126/science.1077136 |
- Vlachou D and Komitopoulou K. The chorion genes of the medfly. II. DNA sequence evolution of the autosomal chorion genes s18, s15, s19 and s16 in Diptera. Gene. 2001 May 30;270(1-2):41-52. DOI:10.1016/s0378-1119(01)00482-6 |
- Vlachou D, Lycett G, Sidén-Kiamos I, Blass C, Sinden RE, and Louis C. Anopheles gambiae laminin interacts with the P25 surface protein of Plasmodium berghei ookinetes. Mol Biochem Parasitol. 2001 Feb;112(2):229-37. DOI:10.1016/s0166-6851(00)00371-6 |
- Margos G, Sidén-Kiamos I, Fowler RE, Gillman TR, Spaccapelo R, Lycett G, Vlachou D, Papagiannakis G, Eling WM, Mitchell GH, and Louis C. Myosin A expressions in sporogonic stages of Plasmodium. Mol Biochem Parasitol. 2000 Dec;111(2):465-9. DOI:10.1016/s0166-6851(00)00335-2 |
- Sidén-Kiamos I, Vlachou D, Margos G, Beetsma A, Waters AP, Sinden RE, and Louis C. Distinct roles for pbs21 and pbs25 in the in vitro ookinete to oocyst transformation of Plasmodium berghei. J Cell Sci. 2000 Oct;113 Pt 19:3419-26. DOI:10.1242/jcs.113.19.3419 |
- Vlachou D, Konsolaki M, Tolias PP, Kafatos FC, and Komitopoulou K. The autosomal chorion locus of the medfly Ceratitis capitata. I. Conserved synteny, amplification and tissue specificity but sequence divergence and altered temporal regulation. Genetics. 1997 Dec;147(4):1829-42. DOI:10.1093/genetics/147.4.1829 |
Recent publications in international conferences
• Mendes A, Bushell SC, Akinosoglou K, Schlegelmilch T, Kafatos FC, Morlais I and Vlachou D. Interactions between A. gambiae and sympatric P. falciparum populations in Africa. 4th EMBO Meeting on Vector Biology, Kolymbari, Crete, 2009.
• Bushell ES, Schlegelmilch T, Ecker A, Goulding D, Sinden RE, Christophides GK, Kafatos FC, Vlachou D. The identification and characterisation of MISFIT, a Plasmodium Male-Inherited Sporulation Factor Important for Malaria Transmission. The 19th Annual Molecular Parasitology Meeting at the Marine Biological Laboratory in Woods Hole, MA. USA, 2008.
• Bushell ESC & Vlachou D. Identification and characterisation of Plasmodium genes responsible for oocyst development and putative evasion of mosquito immune responses. Third Annual BioMalPar Conference, Heidelberg, Germany, 2007.
• Mendes A, Morlais I, Cohuet A, Fontenille D, Christophides GK, , Kafatos FC and Vlachou D. Genomic analysis of mosquito/parasite molecular interactions in natural and model laboratory transmission systems. Fourth Annual International BioMalPar Conference, Heidelberg, Germany, 2008.
• Genomic analysis of Anopheles gambiae responses to sympatric Plasmodium falciparum isolates. Mendes A, Cohuet A, Schlegelmilch T, Morlais I, Fontenille D, Christophides GK, Kafatos FC and Vlachou D. Third Annual BioMalPar Conference, Heidelberg, Germany, 2007.
• Vlachou D, Cohuet A, Mendes A, Morlais I, Fontenille D, Christophides GK, Kafatos FC. Anopheles-Plasmodium interactions: From lab models to natural field transmission. Second Annual BioMalPar Conference, Heidelberg, Germany, 2006.
• Mendes A, Schlegelmilch T, Cohuet A, Morlais I, Simard F, Fontenille D, Christophides GK, Kafatos FC and Vlachou D. Comparative genomic analysis of the Anopheles gambiae responses to infection with Plasmodium falciparum and Plasmodium berghei. Second Annual International BioMalPar Conference, Heidelberg, Germany, 2006.
• Functional genomics of mosquito midgut invasion and the role of Apolipophorins in parasite infections. Schlegelmilch T, Mendes A, Cohuet A, Kafatos FC and Vlachou D. The 11th Annual and International Congress of Parasitology (ICOPA XI), hosted by the British Society for Parasitology, Glasgow, 2006.