Kathleen McGinness

From OpenWetWare

(Difference between revisions)
Jump to: navigation, search
(Publications)
Current revision (23:02, 1 July 2009) (view source)
 
(35 intermediate revisions not shown.)
Line 1: Line 1:
[[Image:Mcginness2.jpg|thumb|right|]]
[[Image:Mcginness2.jpg|thumb|right|]]
-
==Education/Work Experience==
 
-
*Postdoc in the [http://web.mit.edu/biology/sauerlab/ Sauer Lab] at [http://web.mit.edu/ MIT]
 
-
*Ph.D. in Chemistry, [http://www.scripps.edu/e_index.html The Scripps Research Institute], 2001 (with [http://www.scripps.edu/mb/joyce/joycelab.html Gerald Joyce])
+
*Postdoc in the [http://mit.edu/sauerlab/ Sauer lab] at [http://web.mit.edu/ MIT] (2001–2006)
 +
**[[Sauer Lab|Sauer lab OWW page]]
-
*B.S. in Chemistry, [http://www.umd.edu University of Maryland College Park], 1996
+
==Fun facts==
-
*B.S. in Psychology, University of Maryland College Park, 1996
 
 +
*'''Who's visiting?'''
-
== Science stuff I know something about... ==
+
<html>
 +
<a href="http://clustrmaps.com/counter/maps.php?url=http://openwetware.org/wiki/Kathleen_McGinness" id="clustrMapsLink"><img src="http://clustrmaps.com/counter/index2.php?url=http://openwetware.org/wiki/Kathleen_McGinness" border=1 alt="Locations of visitors to this page"onError="this.onError=null; this.src='http://www.meetomatic.com/images/clustrmaps-back-soon.jpg'; document.getElementById('clustrMapsLink').href='http://clustrmaps.com/'">
 +
</a>
 +
</html>
-
*tmRNA (or SsrA/10Sa RNA for you purists)
+
*Here is an excellent tutorial on how [http://video.google.com/videoplay?docid=-2657697036715872139 translation] works, with an introduction by the 1971 version of nobel laureate [http://nobelprize.org/chemistry/laureates/1980/berg-cv.html Paul Berg]. I'd like to see it in classrooms everywhere. '''tRNA! peptide bond!'''
-
 
+
-
*translation
+
-
 
+
-
*energy-dependent proteolysis in bacteria
+
-
 
+
-
*The RNA World
+
-
 
+
-
*molecular biology in a world without kits
+
-
 
+
-
*''in vitro'' selection and evolution of nucleic acids
+
-
 
+
-
*generation of nucleic acid and protein libraries
+
-
 
+
-
*''in vitro'' RNA techniques
+
-
 
+
-
*nucleic acid-protein interactions
+
-
 
+
-
*fishing experiments to look for things that interact with your RNA/DNA/protein of interest
+
-
 
+
-
*PCR (even colony PCR, although it is '''not''' a separate skill)
+
-
 
+
-
*bacterial protein expression/purification
+
-
 
+
-
*''in vivo'' assays with ''E. coli'' i.e. analyzing effects on proteins/RNA
+
-
 
+
-
*molecular cloning
+
-
 
+
-
*Western/Northern/Southern blot analysis
+
-
 
+
-
*oligonucleotide synthesis
+
-
 
+
-
*RNA/DNA sequencing
+
-
 
+
-
*structural probing of RNA/DNA
+
-
 
+
-
*gels, all kinds of gels: agarose, native acrylamide,  denaturing acrylamide, SDS-acrylamide, two-dimensional
+
-
 
+
-
*enzyme kinetics
+
-
 
+
-
*radiolabeling nucleic acids and proteins
+
-
 
+
-
=Publications=
+
-
'''Engineering controllable protein degradation.'''
+
-
 
+
-
McGinness, K.E., Baker, T.A. & Sauer, R.T. (2006) Mol. Cell, in press.
+
-
 
+
-
'''[http://www.pnas.org/cgi/content/full/101/37/13454 Ribosomal protein S1 binds mRNA and tmRNA similarly but plays distinct roles in translation of these molecules.]'''
+
-
 
+
-
McGinness, K.E. & Sauer, R.T. (2004) Proc. Natl. Acad. Sci. USA 101, 13454–13459.
+
-
 
+
-
'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12677051&query_hl=1 A Glimpse into tmRNA-mediated Ribosome Rescue.]'''
+
-
 
+
-
Moore, S.D., McGinness, K.E. & Sauer, R.T. (2003)  Science 300, 127–130. (comment)
+
-
 
+
-
'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12573693&query_hl=1 In Search of an RNA Replicase Ribozyme.]'''
+
-
 
+
-
McGinness, K.E. & Joyce, G.F. (2003)  Chem. Biol. 10, 5–14. (review)
+
-
 
+
-
'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12031665&query_hl=1 Continuous In Vitro Evolution of a Ribozyme that Catalyzes Three Successive Nucleotidyl Addition Reactions.]'''
+
-
 
+
-
McGinness, K.E., Wright, M.C. & Joyce, G.F. (2002)  Chem. Biol. 9, 585–596.
+
-
 
+
-
'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11927255&query_hl=1 RNA-Catalyzed RNA Ligation on an External RNA Template.]'''
+
-
 
+
-
McGinness, K.E. & Joyce, G.F. (2002)  Chem. Biol. 9, 297–307.
+
-
 
+
-
'''[http://www.jbc.org/cgi/content/full/277/4/2987 Substitution of Ribonucleotides in the T7 RNA Polymerase Promoter Element.]'''
+
-
 
+
-
McGinness, K.E. & Joyce, G.F. (2002)  J. Biol. Chem. 277, 2987–2991.
+
-
 
+
-
 
+
-
 
+
-
[[KM:Personal|<font size=4>"Personal"</font>]]
+
-
 
+
-
+
-
 
+
-
[[Sauer Lab| Back to the Sauer lab]]
+

Current revision

Fun facts

  • Who's visiting?

Locations of visitors to this page

  • Here is an excellent tutorial on how translation works, with an introduction by the 1971 version of nobel laureate Paul Berg. I'd like to see it in classrooms everywhere. tRNA! peptide bond!
Personal tools