Kathleen McGinness - Revision history

Kathmc at 03:02, 2 July 2009

Kathmc — Thu, 02 Jul 2009 03:02:54 GMT

←Older revision		Revision as of 03:02, 2 July 2009
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	[[Image:Mcginness2.jpg\|thumb\|right\|]]		[[Image:Mcginness2.jpg\|thumb\|right\|]]
-	~~==Work Experience==~~

	*Postdoc in the [http://mit.edu/sauerlab/ Sauer lab] at [http://web.mit.edu/ MIT] (2001–2006)		*Postdoc in the [http://mit.edu/sauerlab/ Sauer lab] at [http://web.mit.edu/ MIT] (2001–2006)
	**[[Sauer Lab\|Sauer lab OWW page]]		**[[Sauer Lab\|Sauer lab OWW page]]
-
-	~~==Education==~~
-
-	*Ph.D. in Chemistry, [http://www.scripps.edu/e_index.html The Scripps Research Institute], 2001
-	*B.S. in Chemistry, [http://www.umd.edu University of Maryland College Park], 1996
-
-	*B.S. in Psychology, University of Maryland College Park, 1996
-
-	~~==Publications==~~
-	'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17317664&query_hl=1&itool=pubmed_docsum Altered tethering of the SspB adaptor to the ClpXP protease causes changes in substrate delivery.]'''
-
-	~~McGinness K.E., Bolon, D.N., Kaganovich, M., Baker, T.A. & Sauer, R.T. (2007) J. Biol. Chem., 282, 11465-11473. Epub 2007 Feb 22.~~
-
-	~~'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16762842&query_hl=1&itool=pubmed_docsum Engineering controllable protein degradation.]'''~~
-
-	~~McGinness, K.E., Baker, T.A. & Sauer, R.T. (2006) Mol. Cell, 22, 701-707.~~
-
-	~~'''[http://www.pnas.org/cgi/content/full/101/37/13454 Ribosomal protein S1 binds mRNA and tmRNA similarly but plays distinct roles in translation of these molecules.]'''~~
-
-	~~McGinness, K.E. & Sauer, R.T. (2004) Proc. Natl. Acad. Sci. USA 101, 13454–13459.~~
-
-	~~'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12677051&query_hl=1 A Glimpse into tmRNA-mediated Ribosome Rescue.]'''~~
-
-	~~Moore, S.D., McGinness, K.E. & Sauer, R.T. (2003) Science 300, 127–130. (comment)~~
-
-	~~'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12573693&query_hl=1 In Search of an RNA Replicase Ribozyme.]'''~~
-
-	~~McGinness, K.E. & Joyce, G.F. (2003) Chem. Biol. 10, 5–14. (review)~~
-
-	'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12031665&query_hl=1 Continuous In Vitro Evolution of a Ribozyme that Catalyzes Three Successive Nucleotidyl Addition Reactions.]'''
-
-	~~McGinness, K.E., Wright, M.C. & Joyce, G.F. (2002) Chem. Biol. 9, 585–596.~~
-
-	~~'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11927255&query_hl=1 RNA-Catalyzed RNA Ligation on an External RNA Template.]'''~~
-
-	~~McGinness, K.E. & Joyce, G.F. (2002) Chem. Biol. 9, 297–307.~~
-
-	~~'''[http://www.jbc.org/cgi/content/full/277/4/2987 Substitution of Ribonucleotides in the T7 RNA Polymerase Promoter Element.]'''~~
-
-	~~McGinness, K.E. & Joyce, G.F. (2002) J. Biol. Chem. 277, 2987–2991.~~
-
-	~~==Contact==~~
-	~~If you're on [[Main Page\|OWW]], post a message on my [[User talk:Kathmc\|talk page]], or send me an [[Special:Emailuser/Kathmc\|email]].<br>~~
-
-	~~If you're not on OWW, [[OpenWetWare: How to join\|join now]]! <br>~~

	==Fun facts==		==Fun facts==


-	*'''Who's visiting?''' ~~(Thanks [[Barry Canton\|Barry]]!)~~	+	*'''Who's visiting?'''

	<html>		<html>

Kathmc at 04:58, 15 February 2009

Kathmc — Sun, 15 Feb 2009 04:58:35 GMT

←Older revision		Revision as of 04:58, 15 February 2009
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	==Work Experience==		==Work Experience==

-	*Scientist, [http://www.archemix.com/ Archemix Corp.] (2006–??)
	*Postdoc in the [http://mit.edu/sauerlab/ Sauer lab] at [http://web.mit.edu/ MIT] (2001–2006)		*Postdoc in the [http://mit.edu/sauerlab/ Sauer lab] at [http://web.mit.edu/ MIT] (2001–2006)
	**[[Sauer Lab\|Sauer lab OWW page]]		**[[Sauer Lab\|Sauer lab OWW page]]
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	==Education==		==Education==

-	*Ph.D. in Chemistry, [http://www.scripps.edu/e_index.html The Scripps Research Institute], 2001 ~~(with [http://www.scripps.edu/mb/joyce/joycelab.html Gerald Joyce])~~	+	*Ph.D. in Chemistry, [http://www.scripps.edu/e_index.html The Scripps Research Institute], 2001
-		+	*B.S. in Chemistry, [http://www.umd.edu University of Maryland College Park], 1996
-	*B.S. in Chemistry, [http://www.umd.edu University of Maryland College Park], 1996 ~~(with [http://biophysics.jhu.edu/woodson/index.html Sarah Woodson])~~	+

	*B.S. in Psychology, University of Maryland College Park, 1996		*B.S. in Psychology, University of Maryland College Park, 1996
-
-	~~== Science stuff I know something about... ==~~
-
-	*tmRNA (or SsrA/10Sa RNA for you purists)
-
-	*translation
-
-	*energy-dependent proteolysis in bacteria
-
-	*The RNA World
-
-	*molecular biology in a world without kits
-
-	*''in vitro'' selection and evolution of nucleic acids
-
-	*generation of nucleic acid and protein libraries
-
-	*''in vitro'' RNA techniques
-
-	*nucleic acid-protein interactions (''in vitro'' analysis and bacterial ''in vivo'' analysis)
-
-	*fishing experiments to look for things that interact with your RNA/DNA/protein of interest
-
-	*PCR (even colony PCR, although it is '''not''' a separate skill)
-
-	*bacterial protein expression/purification
-
-	*''in vivo'' assays with ''E. coli'' i.e. analyzing effects on proteins/RNA
-
-	*molecular cloning
-
-	*Western/Northern/Southern blot analysis
-
-	*oligonucleotide synthesis
-
-	*RNA/DNA sequencing ("old school" and "new school" techniques)
-
-	*chemical and enzymatic structural probing of RNA/DNA
-
-	*gels, all kinds of gels: agarose, native acrylamide, denaturing acrylamide, SDS-acrylamide, two-dimensional
-
-	*enzyme kinetics
-
-	*radiolabeling nucleic acids and proteins
-
-	*familiarity with some biophysical techniques (a bit of CD spectroscopy, a small amount of analytical ultracentrifugation)
-
-	*fluorescence spectroscopy (nothing too fancy: straight-up fluorescence and a bit of anisotropy)

	==Publications==		==Publications==

Kathmc: /* Fun facts */

Kathmc — Sun, 15 Feb 2009 04:56:08 GMT

Fun facts

←Older revision		Revision as of 04:56, 15 February 2009
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	==Fun facts==		==Fun facts==

-	*[[Special:Contributions/Kathmc\|My OWW contributions.]]

	*'''Who's visiting?''' (Thanks [[Barry Canton\|Barry]]!)		*'''Who's visiting?''' (Thanks [[Barry Canton\|Barry]]!)
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	*Here is an excellent tutorial on how [http://video.google.com/videoplay?docid=-2657697036715872139 translation] works, with an introduction by the 1971 version of nobel laureate [http://nobelprize.org/chemistry/laureates/1980/berg-cv.html Paul Berg]. I'd like to see it in classrooms everywhere. '''tRNA! peptide bond!'''		*Here is an excellent tutorial on how [http://video.google.com/videoplay?docid=-2657697036715872139 translation] works, with an introduction by the 1971 version of nobel laureate [http://nobelprize.org/chemistry/laureates/1980/berg-cv.html Paul Berg]. I'd like to see it in classrooms everywhere. '''tRNA! peptide bond!'''
-
-	~~[[KM:Personal\|<font size=4>"Personal"</font>]]~~

Kathmc at 04:54, 15 February 2009

Kathmc — Sun, 15 Feb 2009 04:54:31 GMT

←Older revision		Revision as of 04:54, 15 February 2009
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-	*~~Other former WFJL crew on OWW: [[Roshan Kumar]], [[User:Wmshih\|William Shih]]~~	+	*Here is an excellent tutorial on how [http://video.google.com/videoplay?docid=-2657697036715872139 translation] works, with an introduction by the 1971 version of nobel laureate [http://nobelprize.org/chemistry/laureates/1980/berg-cv.html Paul Berg]. I'd like to see it in classrooms everywhere. '''tRNA! peptide bond!'''
-	**Related former TSRI folk on OWW: [[Plachikkat Radha]]	+
-		+
-	~~===Important things I've learned through real life experiences.===~~	+
-	*If you can't fix it with duct tape, a safety pin, or both, you should probably just throw it out.	+
-	*Almost everything is ~~better with bacon.~~	+
-	*Lots of things are better with a poached or fried egg on ~~top.~~	+
-	*Never underestimate the importance of your [http://en.~~wikipedia~~.~~org~~/~~wiki/Karass karass~~] ~~(although I like [http://oook.info/bloggery/karass.html this] definition better) and beware~~ of [http://~~en.wikipedia~~.org/~~wiki~~/~~Granfalloon granfalloons].~~	+
-	*Very few people know who [http://en.~~wikipedia.org/wiki/Foghorn_Leghorn Foghorn Leghorn~~] is.	+

	[[KM:Personal\|<font size=4>"Personal"</font>]]		[[KM:Personal\|<font size=4>"Personal"</font>]]

Kathmc at 01:15, 24 October 2007

Kathmc — Wed, 24 Oct 2007 01:15:55 GMT

←Older revision		Revision as of 01:15, 24 October 2007
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	McGinness K.E., Bolon, D.N., Kaganovich, M., Baker, T.A. & Sauer, R.T. (2007) J. Biol. Chem., 282, 11465-11473. Epub 2007 Feb 22.		McGinness K.E., Bolon, D.N., Kaganovich, M., Baker, T.A. & Sauer, R.T. (2007) J. Biol. Chem., 282, 11465-11473. Epub 2007 Feb 22.
		+
	'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16762842&query_hl=1&itool=pubmed_docsum Engineering controllable protein degradation.]'''		'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16762842&query_hl=1&itool=pubmed_docsum Engineering controllable protein degradation.]'''

Kathmc: /* Publications */

Kathmc — Wed, 18 Apr 2007 01:55:41 GMT

Publications

←Older revision		Revision as of 01:55, 18 April 2007
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	'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17317664&query_hl=1&itool=pubmed_docsum Altered tethering of the SspB adaptor to the ClpXP protease causes changes in substrate delivery.]'''		'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17317664&query_hl=1&itool=pubmed_docsum Altered tethering of the SspB adaptor to the ClpXP protease causes changes in substrate delivery.]'''

-	McGinness K.E., Bolon, D.N., Kaganovich, M., Baker, T.A. & Sauer, R.T. (2007) J. Biol. Chem., Feb 22 ~~[Epub ahead of print]~~	+	McGinness K.E., Bolon, D.N., Kaganovich, M., Baker, T.A. & Sauer, R.T. (2007) J. Biol. Chem., 282, 11465-11473. Epub 2007 Feb 22.
-		+
	'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16762842&query_hl=1&itool=pubmed_docsum Engineering controllable protein degradation.]'''		'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16762842&query_hl=1&itool=pubmed_docsum Engineering controllable protein degradation.]'''

Kathmc: /* Important things I've learned through real life experiences. */

Kathmc — Wed, 04 Apr 2007 03:18:17 GMT

Important things I've learned through real life experiences.

←Older revision		Revision as of 03:18, 4 April 2007
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	*If you can't fix it with duct tape, a safety pin, or both, you should probably just throw it out.		*If you can't fix it with duct tape, a safety pin, or both, you should probably just throw it out.
	*Almost everything is better with bacon.		*Almost everything is better with bacon.
		+	*Lots of things are better with a poached or fried egg on top.
	*Never underestimate the importance of your [http://en.wikipedia.org/wiki/Karass karass] (although I like [http://oook.info/bloggery/karass.html this] definition better) and beware of [http://en.wikipedia.org/wiki/Granfalloon granfalloons].		*Never underestimate the importance of your [http://en.wikipedia.org/wiki/Karass karass] (although I like [http://oook.info/bloggery/karass.html this] definition better) and beware of [http://en.wikipedia.org/wiki/Granfalloon granfalloons].
	*Very few people know who [http://en.wikipedia.org/wiki/Foghorn_Leghorn Foghorn Leghorn] is.		*Very few people know who [http://en.wikipedia.org/wiki/Foghorn_Leghorn Foghorn Leghorn] is.

	[[KM:Personal\|<font size=4>"Personal"</font>]]		[[KM:Personal\|<font size=4>"Personal"</font>]]

Kathmc: /* Publications */

Kathmc — Sun, 25 Feb 2007 16:08:12 GMT

Publications

←Older revision		Revision as of 16:08, 25 February 2007
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	==Publications==		==Publications==
		+	'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17317664&query_hl=1&itool=pubmed_docsum Altered tethering of the SspB adaptor to the ClpXP protease causes changes in substrate delivery.]'''
		+
		+	McGinness K.E., Bolon, D.N., Kaganovich, M., Baker, T.A. & Sauer, R.T. (2007) J. Biol. Chem., Feb 22 [Epub ahead of print]
		+
	'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16762842&query_hl=1&itool=pubmed_docsum Engineering controllable protein degradation.]'''		'''[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16762842&query_hl=1&itool=pubmed_docsum Engineering controllable protein degradation.]'''

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	'''[http://www.jbc.org/cgi/content/full/277/4/2987 Substitution of Ribonucleotides in the T7 RNA Polymerase Promoter Element.]'''		'''[http://www.jbc.org/cgi/content/full/277/4/2987 Substitution of Ribonucleotides in the T7 RNA Polymerase Promoter Element.]'''

-	McGinness, K.E. & Joyce, G.F. (2002) J. Biol. Chem. 277, 2987–2991.	+	McGinness, K.E. & Joyce, G.F. (2002) J. Biol. Chem. 277, 2987–2991.

	==Contact==		==Contact==

Kathmc: /* Work Experience */

Kathmc — Thu, 02 Nov 2006 02:10:47 GMT

Work Experience

←Older revision		Revision as of 02:10, 2 November 2006
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	==Work Experience==		==Work Experience==

		+	*Scientist, [http://www.archemix.com/ Archemix Corp.] (2006–??)
	*Postdoc in the [http://mit.edu/sauerlab/ Sauer lab] at [http://web.mit.edu/ MIT] (2001–2006)		*Postdoc in the [http://mit.edu/sauerlab/ Sauer lab] at [http://web.mit.edu/ MIT] (2001–2006)
	**[[Sauer Lab\|Sauer lab OWW page]]		**[[Sauer Lab\|Sauer lab OWW page]]
		+
	==Education==		==Education==

Kathmc: /* Education */

Kathmc — Mon, 23 Oct 2006 00:45:13 GMT

Education

←Older revision		Revision as of 00:45, 23 October 2006
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	*Ph.D. in Chemistry, [http://www.scripps.edu/e_index.html The Scripps Research Institute], 2001 (with [http://www.scripps.edu/mb/joyce/joycelab.html Gerald Joyce])		*Ph.D. in Chemistry, [http://www.scripps.edu/e_index.html The Scripps Research Institute], 2001 (with [http://www.scripps.edu/mb/joyce/joycelab.html Gerald Joyce])

-	*B.S. in Chemistry, [http://www.umd.edu University of Maryland College Park], 1996	+	*B.S. in Chemistry, [http://www.umd.edu University of Maryland College Park], 1996 (with [http://biophysics.jhu.edu/woodson/index.html Sarah Woodson])

	*B.S. in Psychology, University of Maryland College Park, 1996		*B.S. in Psychology, University of Maryland College Park, 1996