Keasling: Synthetic Biology Class/References

Readings for 1/25/2006:

Engineering a mevalonate pathway in Escherichia coli for production of terpenoids. [[1]]

Synthetic biology: engineering Escherichia coli to see light. [[2]]

Reading for 2/1/2006:

Reconstruction of genetic circuits. [[3]]

Reading for 2/8/2006:

Programming cellular function. [[4]]

Metabolic engineering for drug discovery and development. [[5]]

Reading for 2/15/2006:

A synthetic multicellular system for programmed pattern formation. [[6]]

Directed evolution of a genetic circuit. [[7]]

Reading for 2/22/2006:

Programmable ligand-controlled riboregulators of eukaryotic gene expression. [[8]]

Engineered riboregulators enable post-transcriptional control of gene expression. [[9]]

Reading for 3/1/2006:

Computational design of a biologically active enzyme. [[10]]

Designed divergent evolution of enzyme function. [[11]]

Reading for 3/8/2006:

Lessons from natural molecules. Media:walsh.pdf

The secondary metabolites and biosynthetic gene clusters of marine cyanobacteria. Applications in biotechnology. Media:Gerwick_et_al_Chapter_in_Proksch_book.pdf

Reading for 3/15/2006:

Reprogramming control of an allosteric signaling swith through modular recombination. Media:1904.pdf

The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway. Media:822.pdf