Keymer
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We study the molecular biophysics and spatial evolutionary ecology of microbial (bacteria, phages & plasmids) and cellular (monocytes & macrophages) assemblages in nanofabricated adaptive (<i>habitat</i>) landscapes. We combine theoretical biology with experimental biophysics to study systems biology in nano-scale on-chip ecosystems.<br> | We study the molecular biophysics and spatial evolutionary ecology of microbial (bacteria, phages & plasmids) and cellular (monocytes & macrophages) assemblages in nanofabricated adaptive (<i>habitat</i>) landscapes. We combine theoretical biology with experimental biophysics to study systems biology in nano-scale on-chip ecosystems.<br> | ||
| - | <b>PHYSICS:</b> We study the interface between "individuals" (<i>cells</i>) and their "environment" (<i>niches</i>). At the nanoscale, this distinction blurs into a soft-matter physical (adaptive) system (<i>organism</i>). We are interested in molecular autopoiesis, self-regeneration, self-assembly, and adaptation (computation?) in biophysical evolutionary systems (instances of replicator-interactor cycles). <br> | + | <b>PHYSICS:</b> We study the interface between "individuals" (<i>cells & replicons</i>) and their "environment" (<i>niches</i>). At the nanoscale, this distinction blurs into a soft-matter physical (adaptive) system (<i>organism</i>). We are interested in molecular autopoiesis, self-regeneration, self-assembly, and adaptation (computation?) in biophysical evolutionary systems (instances of replicator-interactor cycles). <br> |
<b>TECHNOLOGY:</b> We are interested in evolving <i>metabolism</i> into physical materials to provide biology-based functionality to human-built devices. We see nano-bio as the natural outcome of the evolutionary trajectory of technology. It corresponds to the adaptive radiation into the nanoscopic world within the (human) built-environment. | <b>TECHNOLOGY:</b> We are interested in evolving <i>metabolism</i> into physical materials to provide biology-based functionality to human-built devices. We see nano-bio as the natural outcome of the evolutionary trajectory of technology. It corresponds to the adaptive radiation into the nanoscopic world within the (human) built-environment. | ||


