Kim

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[[Kim | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''HOME''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
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[[Kim:Hall_Of_Fame | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''HALL OF FAME''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
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<h3>Overview</h3>
<h3>Overview</h3>
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<font size=3>Our research spans the disciplinary boundaries between biomaterials, nanotechnology, and cell mechanobiology with an emphasis on their applications to tissue engineering and regenerative medicine. Through the use of multiscale (nano/micro/meso) fabrication and integration tools, we focus on the development and applications of biomimetic cell culture models and functional tissue engineering constructs for high-throughput drug screening, stem cell-based therapies, disease diagnostics, and medical device development. Using engineered microenvironments in combination with quantitative live cell imaging approaches, we are also studying the interplay between mechanical and biochemical signaling in the regulation of cell function and fate decisions that are essential for tissue repair and regeneration following injury, and various developmental events. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multiscale regenerative technologies for improving human health. </font>
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Our research spans the disciplinary boundaries between nanotechnology, biomaterials, and mechanobiology with an emphasis on their applications to tissue engineering and regenerative medicine. Through the use of multi-scale (nano/micro/meso) fabrication and integration tools, we focus on the development and application of bio-inspired materials/devices and functional tissue engineering models for elucidating regenerative biology, drug screening, disease modeling, and stem cell-based therapies. Using engineered microenvironments in combination with quantitative live cell imaging approaches, we are also studying the intricate interactions between mechanical and biochemical signaling in the regulation of cell/tissue function and fate decisions that are essential for tumor progression and metastasis, tissue repair and regeneration following injury, and various developmental events. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multi-scale regenerative technologies for improving human health.  
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<h3>News</h3>  
<h3>News</h3>  
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* D. Kim joins the Editorial Board of the [http://digital-library.theiet.org/content/journals/iet-nbt '''IET Nanobiotechnology journal''']  (Jan. 2013)  
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* Prof. Kim has been promoted to Associate Professor with Tenure! (06/2017)
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* Cameron Nemeth received The SLUG Symposium Undergraduate Student Award (2012)
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* Kim lab has been awarded a NIH R01 grant! (02/2017)
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* Derek Britain, Sam Frankel, Cameron Nemeth, and Nicole Trosper have been awarded for Mary Gates Undergraduate Research Scholarship (2012)
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* Peter Kim has been awarded the AHA Predoctoral Fellowship! (12/2014)
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* D. Kim appointed as program committee member of [http://www.ieee-nanomed.org/2012/ '''IEEE International Conference on Nano/Molecular Medicine and Engineering''']   (2012)
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* Cameron Nemeth has been given a BMES Undergraduate Design and Research Award and the Washington Research Foundation Fellowship. (Sept. 2013) [http://depts.washington.edu/bioe/cameron-nemeth-receives-bmes-award-wrf-fellowship/ Read more] 
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* D. Kim co-organized the first USACM Thematic Conference on Multiscale Methods and Validation in Medicine and Biology: Biomechanics and Mechanobiology (Jan. 2012)
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* Prof. Kim has been awarded the prestigious Young Investigator Award 2013 from the [http://ksea.org/index.php?option=com_content&view=article&id=521:2013yigwinners&catid=11:upcoming-events&Itemid=48 Korean-American Scientists and Engineers Association (KSEA)]. (06/2013)
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* D. Kim gave an invited talk at the 5th International Conference on Cell Therapy, Seoul, Korea (Nov. 2011)
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* Prof. Kim joined the editorial board of the [http://www.aspbs.com/jbn.html Journal of Biomedical Nanotechnology] as an Associate Editor. (05/ 2013)
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* Kim Lab has been awarded an [http://mda.org/research/gaag/dmd-deok-ho-kim-phd Muscular Dystrophy Association (MDA) research grant] to develop bioengineering techniques for growing muscle for use in transplantation into a mouse model of Duchenne muscular dystrophy. (02/2013)
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<h3>Featured Publications</h3>  
<h3>Featured Publications</h3>  
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* Nanopatterned cardiac cell patches promote stem cell niche formation and myocardial regeneration, Integrative Biology, Vol. 4, Issue 9,pp. 1019-1033, 2012 [http://pubs.rsc.org/en/journals/journalissues/ib#!issueid=ib004009&type=current&issnprint=1757-9694 '''(Featured Cover Article)''']    [http://pubs.rsc.org/en/content/articlelanding/2012/ib/c2ib20067h Article]<br>
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*Thermoresponsive nanofabricated substratum for the engineering of three-dimensional tissues with layer-by-layer architectural control, ACS Nano, vol. 8, pp. 4430-4439, 2014. [http://pubs.acs.org/doi/abs/10.1021/nn4063962 Article]
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* Nanopatterned muscle cell patches for enhanced myogenesis and dystrophin expression in a mouse model of muscular dystrophy, Biomaterials, vol. 35, pp. 1478-1486, 2014. [http://www.sciencedirect.com/science/article/pii/S0142961213013239 Article]
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* Nanotopography-guided tissue engineering and regenerative medicine, Advanced Drug Delivery Review, vol. 65, pp. 536-558, 2013. [http://www.sciencedirect.com/science/journal/0169409X/65/4 '''(Featured as a Cover Article)'''] [http://www.sciencedirect.com/science/article/pii/S0169409X1200244X Article]
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* Nanopatterned cardiac cell patches promote stem cell niche formation and myocardial regeneration, Integrative Biology, Vol. 4, Issue 9,pp. 1019-1033, 2012 [http://pubs.rsc.org/en/journals/journalissues/ib#!issueid=ib004009&type=current&issnprint=1757-9694 '''(Featured as a Cover Article)''']    [http://pubs.rsc.org/en/content/articlelanding/2012/ib/c2ib20067h Article]<br>
* Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors, Science Signaling, vol. 5, issue 227, p. ra41, 2012. [http://stke.sciencemag.org/content/vol5/issue227/cover.dtl '''(Featured as a Cover Article)''']  [http://stke.sciencemag.org/cgi/content/abstract/sigtrans;5/227/ra41 Article]
* Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors, Science Signaling, vol. 5, issue 227, p. ra41, 2012. [http://stke.sciencemag.org/content/vol5/issue227/cover.dtl '''(Featured as a Cover Article)''']  [http://stke.sciencemag.org/cgi/content/abstract/sigtrans;5/227/ra41 Article]
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* Engineering neuronal growth cone to promote axon regeneration over inhibitory molecules, Proceedings of the National Academy of Sciences USA, vol. 108, pp. 5057-5062, 2011. [http://www.pnas.org/content/early/2011/03/03/1011258108.full.pdf+html Article]<BR>
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* Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs, Proceedings of National Academy of Sciences USA, vol.107, pp. 565-570, 2010. [http://www.pnas.org/content/107/2/565.long Article] [http://www.nibib.nih.gov/HealthEdu/eAdvances/30July10 '''(Highlighted in the National Institute of Biomedical Imaging and Bioengineering)]'''
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* Biomimetic nanopatterns as enabling tools for analysis and control of live cells, Advanced Materials, 2010. [http://www.ncbi.nlm.nih.gov/pubmed/20803528 Pubmed], [http://www.hubmed.org/display.cgi?uids=20803528 Hubmed] <BR>
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* Microengineered platforms for cell mechanobiology, Annual Review of Biomedical Engineering, vol. 11, pp.203-233, 2009. [http://www.annualreviews.org/doi/abs/10.1146/annurev-bioeng-061008-124915?url_ver=Z39.88-2003&rfr_dat=cr_pub%3Dpubmed&rfr_id=ori%3Arid%3Acrossref.org&journalCode=bioeng Article]
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* Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs, Proceedings of National Academy of Sciences USA, vol.107, pp. 565-570, 2010. [http://www.ncbi.nlm.nih.gov/pubmed/20018748 Pubmed], [http://www.hubmed.org/display.cgi?uids=20018748 Hubmed] <BR>
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<font size = 3> '''Our Sponsors''': <br>
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[[Image: nsf_Logo.jpg|100px|link=http://mda.org/]] &emsp;&emsp;
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[[Image: NIH banner.png|220px|link = http://www.nih.gov/]] &emsp;&emsp;
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[[Image: AHA.jpg|140px|link = http://www.heart.org/HEARTORG/]] &emsp;&emsp;
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[[Image: MDAlogo name.jpg|200px|link=http://mda.org/]] &emsp;&emsp;
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[[Image:MOTIE-logo.jpg|180px|link=http://www.mke.go.kr/language/eng/]] &emsp;&emsp; <br>
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[[Image: Coulter.jpg|100px|link =http://www.whcf.org/]]  &emsp;&emsp;
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[[Image: C4C.png|160px|link = http://depts.washington.edu/uwc4c/]] &emsp;&emsp;&emsp;&emsp; 
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[[Image: Lsdf_logo2.gif‎|140px|link = http://www.lsdfa.org/]] &emsp;&emsp;
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[[Image: UWlogo.jpg|220px|link = http://www.washington.edu/]] &emsp;&emsp;
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[[Image:KSEAlogo.jpg|220px|link = http://www.ksea.org/2013/]] &emsp;&emsp; <br>
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<div style="text-align: left;">[http://www2.clustrmaps.com/user/a76c219e http://www2.clustrmaps.com/stats/maps-no_clusters/www.openwetware.org-wiki-Kim-thumb.jpg] </div>
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Current revision

HOME       RESEARCH       PUBLICATIONS       PEOPLE       HALL OF FAME       NEWS       POSITIONS       OUTREACH       INTERNAL       CONTACT      


Overview

Our research spans the disciplinary boundaries between nanotechnology, biomaterials, and mechanobiology with an emphasis on their applications to tissue engineering and regenerative medicine. Through the use of multi-scale (nano/micro/meso) fabrication and integration tools, we focus on the development and application of bio-inspired materials/devices and functional tissue engineering models for elucidating regenerative biology, drug screening, disease modeling, and stem cell-based therapies. Using engineered microenvironments in combination with quantitative live cell imaging approaches, we are also studying the intricate interactions between mechanical and biochemical signaling in the regulation of cell/tissue function and fate decisions that are essential for tumor progression and metastasis, tissue repair and regeneration following injury, and various developmental events. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multi-scale regenerative technologies for improving human health.

News

  • Prof. Kim has been promoted to Associate Professor with Tenure! (06/2017)
  • Kim lab has been awarded a NIH R01 grant! (02/2017)
  • Peter Kim has been awarded the AHA Predoctoral Fellowship! (12/2014)
  • Cameron Nemeth has been given a BMES Undergraduate Design and Research Award and the Washington Research Foundation Fellowship. (Sept. 2013) Read more
  • Prof. Kim has been awarded the prestigious Young Investigator Award 2013 from the Korean-American Scientists and Engineers Association (KSEA). (06/2013)
  • Prof. Kim joined the editorial board of the Journal of Biomedical Nanotechnology as an Associate Editor. (05/ 2013)
  • Kim Lab has been awarded an Muscular Dystrophy Association (MDA) research grant to develop bioengineering techniques for growing muscle for use in transplantation into a mouse model of Duchenne muscular dystrophy. (02/2013)



Featured Publications

  • Thermoresponsive nanofabricated substratum for the engineering of three-dimensional tissues with layer-by-layer architectural control, ACS Nano, vol. 8, pp. 4430-4439, 2014. Article
  • Nanopatterned muscle cell patches for enhanced myogenesis and dystrophin expression in a mouse model of muscular dystrophy, Biomaterials, vol. 35, pp. 1478-1486, 2014. Article
  • Nanotopography-guided tissue engineering and regenerative medicine, Advanced Drug Delivery Review, vol. 65, pp. 536-558, 2013. (Featured as a Cover Article) Article
  • Nanopatterned cardiac cell patches promote stem cell niche formation and myocardial regeneration, Integrative Biology, Vol. 4, Issue 9,pp. 1019-1033, 2012 (Featured as a Cover Article) Article
  • Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors, Science Signaling, vol. 5, issue 227, p. ra41, 2012. (Featured as a Cover Article) Article
  • Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs, Proceedings of National Academy of Sciences USA, vol.107, pp. 565-570, 2010. Article (Highlighted in the National Institute of Biomedical Imaging and Bioengineering)
  • Microengineered platforms for cell mechanobiology, Annual Review of Biomedical Engineering, vol. 11, pp.203-233, 2009. Article

[| University of Washington ]      [| College of Engineering ]      [| UW Medicine ]      [| UW Bioengineering ]     


Our Sponsors:
link=http://mda.org/    link = http://www.nih.gov/    link = http://www.heart.org/HEARTORG/    link=http://mda.org/    link=http://www.mke.go.kr/language/eng/   
link =http://www.whcf.org/    link = http://depts.washington.edu/uwc4c/      link = http://www.lsdfa.org/    link = http://www.washington.edu/    link = http://www.ksea.org/2013/   

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