Kim

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[[Kim:News | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''NEWS''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
[[Kim:News | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''NEWS''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
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[[Kim:Contact | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''CONTACT''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
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[[Kim:Outreach | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''OUTREACH''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[[Kim:Contact | <font face="trebuchet ms" size=3 style="color:#ffffff"> '''CONTACT''' </font>]] &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
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<h3>Overview</h3>
<h3>Overview</h3>
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<font size=3>Our research spans the disciplinary boundaries between biomaterials, nanotechnology, and cell mechanobiology with an emphasis on their applications to tissue engineering and regenerative medicine. Through the use of multiscale fabrication and integration tools, we focus on the development and applications of biomimetic cell culture models and functional tissue engineering constructs for high-throughput drug screening, stem cell-based therapies, disease diagnostics, and medical device development. Using engineered microenvironments in combination with live cell imaging approaches, we are also studying the interplay between mechanical and biochemical signaling in the regulation of cell function and fate decisions that are essential for tissue repair and regeneration following injury, and various developmental events. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multiscale regenerative technologies for improving human health. </font>
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<font size=3>Our research spans the disciplinary boundaries between biomaterials, nanotechnology, and cell mechanobiology with an emphasis on their applications to tissue engineering and regenerative medicine. Through the use of multiscale (nano/micro/meso) fabrication and integration tools, we focus on the development and applications of biomimetic cell culture models and functional tissue engineering constructs for high-throughput drug screening, stem cell-based therapies, disease diagnostics, and medical device development. Using engineered microenvironments in combination with quantitative live cell imaging approaches, we are also studying the interplay between mechanical and biochemical signaling in the regulation of cell function and fate decisions that are essential for tissue repair and regeneration following injury, and various developmental events. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multiscale regenerative technologies for improving human health. </font>
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<h3>News</h3>  
<h3>News</h3>  
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* D. Kim was appointed as a Program committee member in [http://www.ieee-nanomed.org/2012/ '''IEEE International Conference on Nano/Molecular Medicine and Engineering''']  (2012)
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* Daniel Lih has been awarded the Mary Gates Undergraduate Research Scholarship!
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* D. Kim attended the first USACM Thematic Conference on Multiscale Methods and Validation in Medicine and Biology: Biomechanics and Mechanobiology as a Organizing committee member (2012)
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* Hee Seok Yang, who was a post doc in the lab, has accepted an offer to start as a faculty member at the Dankook University in Korea. Congratulations! (Feb. 2013)
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* D. Kim was appointed as a Session Chair “Reprogramming and Stem Cell Therapy” session at the 5th International Conference on Cell Therapy, Seoul, Korea (11/01/2011)
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* Alex Jiao, Nicole Trosper, and Justin Lee win the Outstanding Paper Award at the 2013 ASME Global Congress on Nano Engineering for Medicine and Biology (Feb. 2013)
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* D. Kim was a Session Chair of “Biology/micro-TAS, Biomimetics, Self-assembly, Chemistry” session at the 10th International Conference on Nanoimprint and Nanoprint Technology, JeJu, Korea (10/19-21/2011)
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* D. Kim was invited to join the editorial board of the [http://www.springer.com/engineering/electronics/journal/12213 Journal of Micro-Bio Robotics] as an Associate Editor (Jan. 2013)
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* D. Kim joins the honorary Editorial Board of the [http://www.dovepress.com/honorary-editorial-board-international-journal-of-nanomedicine-edboard5 International Journal of Nanomedicine] (Jan. 2013)
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* D. Kim joins the Editorial Board of the [http://digital-library.theiet.org/content/journals/iet-nbt IET Nanobiotechnology Journal]  (Jan. 2013)  
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<h3>Recent Publications</h3>  
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<h3>Featured Publications</h3>  
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*Engineering neuronal growth cone to promote axon regeneration over inhibitory molecules, Proceedings of the National Academy of Sciences USA, vol. 108, pp. 5057-5062, 2011. [http://www.pnas.org/content/early/2011/03/03/1011258108.full.pdf+html Article]<BR>
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* A non-transcriptional role for HIF-1α as a direct inhibitor of DNA replication, Science Signaling, vol. 6, pp. ra10, 2013. [http://stke.sciencemag.org/content/vol6/issue262/cover.dtl '''(Featured as a Cover Article)''']  [http://stke.sciencemag.org/cgi/content/full/sigtrans;6/262/ra10 Article] [http://stke.sciencemag.org/cgi/content/full/sigtrans;6/262/pc5/DC1 Podcast]<br>
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* Nanopatterned cardiac cell patches promote stem cell niche formation and myocardial regeneration, Integrative Biology, Vol. 4, Issue 9,pp. 1019-1033, 2012 [http://pubs.rsc.org/en/journals/journalissues/ib#!issueid=ib004009&type=current&issnprint=1757-9694 '''(Featured Cover Article)''']    [http://pubs.rsc.org/en/content/articlelanding/2012/ib/c2ib20067h Article]<br>
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* Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors, Science Signaling, vol. 5, issue 227, p. ra41, 2012. [http://stke.sciencemag.org/content/vol5/issue227/cover.dtl '''(Featured as a Cover Article)''']  [http://stke.sciencemag.org/cgi/content/abstract/sigtrans;5/227/ra41 Article]
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* Engineering neuronal growth cone to promote axon regeneration over inhibitory molecules, Proceedings of the National Academy of Sciences USA, vol. 108, pp. 5057-5062, 2011. [http://www.pnas.org/content/early/2011/03/03/1011258108.full.pdf+html Article]<BR>
* Biomimetic nanopatterns as enabling tools for analysis and control of live cells, Advanced Materials, 2010. [http://www.ncbi.nlm.nih.gov/pubmed/20803528 Pubmed], [http://www.hubmed.org/display.cgi?uids=20803528 Hubmed] <BR>
* Biomimetic nanopatterns as enabling tools for analysis and control of live cells, Advanced Materials, 2010. [http://www.ncbi.nlm.nih.gov/pubmed/20803528 Pubmed], [http://www.hubmed.org/display.cgi?uids=20803528 Hubmed] <BR>
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* Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs, Proceedings of National Academy of Sciences USA, vol.107, pp. 565-570, 2010. [http://www.ncbi.nlm.nih.gov/pubmed/20018748 Pubmed], [http://www.hubmed.org/display.cgi?uids=20018748 Hubmed] <BR>
 
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* Microengineered platform for cell mechanobiology, Annual Review of Biomedical Engineering, vol. 11, pp.203-233, 2009. [http://www.ncbi.nlm.nih.gov/pubmed/19400708 Pubmed] <BR>
 
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Revision as of 03:08, 4 April 2013

HOME        RESEARCH        PEOPLE        PUBLICATIONS        INTERNAL        POSITIONS        NEWS        LINKS        OUTREACH        CONTACT       

Overview

Our research spans the disciplinary boundaries between biomaterials, nanotechnology, and cell mechanobiology with an emphasis on their applications to tissue engineering and regenerative medicine. Through the use of multiscale (nano/micro/meso) fabrication and integration tools, we focus on the development and applications of biomimetic cell culture models and functional tissue engineering constructs for high-throughput drug screening, stem cell-based therapies, disease diagnostics, and medical device development. Using engineered microenvironments in combination with quantitative live cell imaging approaches, we are also studying the interplay between mechanical and biochemical signaling in the regulation of cell function and fate decisions that are essential for tissue repair and regeneration following injury, and various developmental events. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multiscale regenerative technologies for improving human health.

News

  • Daniel Lih has been awarded the Mary Gates Undergraduate Research Scholarship!
  • Hee Seok Yang, who was a post doc in the lab, has accepted an offer to start as a faculty member at the Dankook University in Korea. Congratulations! (Feb. 2013)
  • Alex Jiao, Nicole Trosper, and Justin Lee win the Outstanding Paper Award at the 2013 ASME Global Congress on Nano Engineering for Medicine and Biology (Feb. 2013)
  • D. Kim was invited to join the editorial board of the Journal of Micro-Bio Robotics as an Associate Editor (Jan. 2013)
  • D. Kim joins the honorary Editorial Board of the International Journal of Nanomedicine (Jan. 2013)
  • D. Kim joins the Editorial Board of the IET Nanobiotechnology Journal (Jan. 2013)



Featured Publications

  • A non-transcriptional role for HIF-1α as a direct inhibitor of DNA replication, Science Signaling, vol. 6, pp. ra10, 2013. (Featured as a Cover Article) Article Podcast
  • Nanopatterned cardiac cell patches promote stem cell niche formation and myocardial regeneration, Integrative Biology, Vol. 4, Issue 9,pp. 1019-1033, 2012 (Featured Cover Article) Article
  • Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors, Science Signaling, vol. 5, issue 227, p. ra41, 2012. (Featured as a Cover Article) Article
  • Engineering neuronal growth cone to promote axon regeneration over inhibitory molecules, Proceedings of the National Academy of Sciences USA, vol. 108, pp. 5057-5062, 2011. Article
  • Biomimetic nanopatterns as enabling tools for analysis and control of live cells, Advanced Materials, 2010. Pubmed, Hubmed

[| University of Washington ]      [| College of Engineering ]      [| UW Medicine ]      [| UW Bioengineering ]     

www.openwetware.org-wiki-Kim-thumb.jpg



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