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<h3>Overview</h3>
<h3>Overview</h3>
<font size=3>Our research spans the disciplinary boundaries between biomaterials, nanotechnology, and cell mechanobiology with an emphasis on their applications to tissue engineering and regenerative medicine. Through the use of multiscale (nano/micro/meso) fabrication and integration tools, we focus on the development and applications of biomimetic materials/devices/systems and functional tissue engineering models for high-throughput drug screening, stem cell-based therapies, disease modeling, and medical device development. Using engineered microenvironments in combination with quantitative live cell imaging approaches, we are also studying the interplay between mechanical and biochemical signaling in the regulation of cell function and fate decisions that are essential for tissue repair and regeneration following injury, and various developmental events. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multiscale regenerative technologies for improving human health. </font>
<font size=3>Our research spans the disciplinary boundaries between nanotechnology, biomaterials, and cell mechanobiology with an emphasis on their applications to tissue engineering and regenerative medicine. Through the use of multiscale (nano/micro/meso) fabrication and integration tools, we focus on the development and applications of bio-inspired materials/devices/systems and functional tissue engineering models for elucidatig cell biology, stem cell-based therapies, disease modeling, and high-throughput drug screening. Using engineered microenvironments in combination with quantitative live cell imaging approaches, we are also studying the interplay between mechanical and biochemical signaling in the regulation of cell/tissue function and fate decisions that are essential for tissue repair and regeneration following injury, and various developmental events. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multiscale regenerative technologies for improving human health. </font>
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<h3>News</h3>  
<h3>News</h3>  
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* Kim Lab has been awarded an Muscular Dystrophy Association (MDA) research grant to develop bioengineering techniques for growing muscle for use in transplantation into a mouse model of Duchenne muscular dystrophy. This works was featured on the [http://mda.org/research/gaag/dmd-deok-ho-kim-phd MDA website] (Apr. 2013)
*The Kim lab has been awarded the [https://www.wnf.washington.edu/ WRF] Microfabrication Commercialization Grant. This award will support our work on development of a next generation integrated MEA-nanodevice for drug-induced cardiotoxicity screening. (Nov. 2013)
* Hee Seok Yang, who was a post doc in the lab, has accepted an offer to start as a faculty member at the Dankook University in Korea. Congratulations! (Feb. 2013)
* Cameron Nemeth has been given a BMES Undergraduate Design and Research Award for his extended abstract for BMES 2013.  Cameron also received the Washington Research Foundation Fellowship. Congratulations Cameron! (Sept. 2013)
* Alex Jiao, Nicole Trosper, and Justin Lee win the Outstanding Paper Award at the 2013 ASME Global Congress on Nano Engineering for Medicine and Biology (Feb. 2013)
* Alex Jiao was awarded a NIH T32 Cardiovascular Pathology Training Grant Fellowship. (Aug. 2013).
* Prof. Kim was invited to join the editorial board of the [http://www.springer.com/engineering/electronics/journal/12213 Journal of Micro-Bio Robotics] as an Associate Editor (Jan. 2013)
* Prof. Kim has been awarded the prestigious Young Investigator Award 2013 from the [http://ksea.org/index.php?option=com_content&view=article&id=521:2013yigwinners&catid=11:upcoming-events&Itemid=48 Korean-American Scientists and Engineers Association (KSEA)]. (June 2013)
* Prof. Kim joins the honorary Editorial Board of the [http://www.dovepress.com/honorary-editorial-board-international-journal-of-nanomedicine-edboard5 International Journal of Nanomedicine] (Jan. 2013)
* Jesse Macadangdang was awarded a NIH Bioengineering Cardiovascular Training Grant Fellowship!  (June 2013)
* Prof. Kim joins the Editorial Board of the [http://digital-library.theiet.org/content/journals/iet-nbt IET Nanobiotechnology Journal]   (Jan. 2013)  
* Daniel Lih was awarded a summer research fellowship from National Yang-Ming University! (June 2013)
* Prof. Kim joined the editorial board of the [http://www.aspbs.com/jbn.html Journal of Biomedical Nanotechnology] as an Associate Editor. (May 2013)
* Kim Lab has been awarded an [http://mda.org/research/gaag/dmd-deok-ho-kim-phd Muscular Dystrophy Association (MDA) research grant] to develop bioengineering techniques for growing muscle for use in transplantation into a mouse model of Duchenne muscular dystrophy. (Feb. 2013)
 




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<font size = 3> '''Our sponsors''': <br>
<font size = 3> '''Our Sponsors''': <br>
[[Image: AHA.jpg|150px]] &emsp;&emsp;  
[[Image: AHA.jpg|160px]] &emsp;&emsp;  
[[Image: MDAlogo name.jpg|220px|link=http://mda.org/]] &emsp;&emsp;  
[[Image: MDAlogo name.jpg|220px|link=http://mda.org/]] &emsp;&emsp;  
[[Image: Coulter.jpg|110px]]  &emsp;&emsp;  
[[Image: nsf_Logo.jpg|120px|link=http://mda.org/]] &emsp;&emsp;
[[Image: C4C.png|190px]] &emsp;&emsp;&emsp;&emsp;   
[[Image: Coulter.jpg|120px]]  &emsp;&emsp;  
[[Image: C4C.png|200px]] &emsp;&emsp;&emsp;&emsp;  <br>
[[Image: Lsdf_logo2.gif‎|160px]] &emsp;&emsp;
[[Image: UWlogo.jpg|240px]] &emsp;&emsp;
[[Image: NIH banner.png|240px]] &emsp;&emsp;
[http://www2.clustrmaps.com/user/a76c219e http://www2.clustrmaps.com/stats/maps-no_clusters/www.openwetware.org-wiki-Kim-thumb.jpg]
[http://www2.clustrmaps.com/user/a76c219e http://www2.clustrmaps.com/stats/maps-no_clusters/www.openwetware.org-wiki-Kim-thumb.jpg]


Revision as of 02:37, 9 January 2014

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Overview

Our research spans the disciplinary boundaries between nanotechnology, biomaterials, and cell mechanobiology with an emphasis on their applications to tissue engineering and regenerative medicine. Through the use of multiscale (nano/micro/meso) fabrication and integration tools, we focus on the development and applications of bio-inspired materials/devices/systems and functional tissue engineering models for elucidatig cell biology, stem cell-based therapies, disease modeling, and high-throughput drug screening. Using engineered microenvironments in combination with quantitative live cell imaging approaches, we are also studying the interplay between mechanical and biochemical signaling in the regulation of cell/tissue function and fate decisions that are essential for tissue repair and regeneration following injury, and various developmental events. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multiscale regenerative technologies for improving human health.

News

  • The Kim lab has been awarded the WRF Microfabrication Commercialization Grant. This award will support our work on development of a next generation integrated MEA-nanodevice for drug-induced cardiotoxicity screening. (Nov. 2013)
  • Cameron Nemeth has been given a BMES Undergraduate Design and Research Award for his extended abstract for BMES 2013. Cameron also received the Washington Research Foundation Fellowship. Congratulations Cameron! (Sept. 2013)
  • Alex Jiao was awarded a NIH T32 Cardiovascular Pathology Training Grant Fellowship. (Aug. 2013).
  • Prof. Kim has been awarded the prestigious Young Investigator Award 2013 from the Korean-American Scientists and Engineers Association (KSEA). (June 2013)
  • Jesse Macadangdang was awarded a NIH Bioengineering Cardiovascular Training Grant Fellowship! (June 2013)
  • Daniel Lih was awarded a summer research fellowship from National Yang-Ming University! (June 2013)
  • Prof. Kim joined the editorial board of the Journal of Biomedical Nanotechnology as an Associate Editor. (May 2013)
  • Kim Lab has been awarded an Muscular Dystrophy Association (MDA) research grant to develop bioengineering techniques for growing muscle for use in transplantation into a mouse model of Duchenne muscular dystrophy. (Feb. 2013)

Featured Publications

  • A non-transcriptional role for HIF-1α as a direct inhibitor of DNA replication, Science Signaling, vol. 6, pp. ra10, 2013. (Featured as a Cover Article) Article Podcast
  • Nanopatterned cardiac cell patches promote stem cell niche formation and myocardial regeneration, Integrative Biology, Vol. 4, Issue 9,pp. 1019-1033, 2012 (Featured Cover Article) Article
  • Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors, Science Signaling, vol. 5, issue 227, p. ra41, 2012. (Featured as a Cover Article) Article
  • Engineering neuronal growth cone to promote axon regeneration over inhibitory molecules, Proceedings of the National Academy of Sciences USA, vol. 108, pp. 5057-5062, 2011. Article
  • Biomimetic nanopatterns as enabling tools for analysis and control of live cells, Advanced Materials, 2010. Pubmed, Hubmed
  • Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs, Proceedings of National Academy of Sciences USA, vol.107, pp. 565-570, 2010. Article (Highlighted in the National Institute of Biomedical Imaging and Bioengineering)
  • Microengineered platforms for cell mechanobiology, Annual Review of Biomedical Engineering, vol. 11, pp.203-233, 2009. Article


Our Sponsors:
                
         http://www2.clustrmaps.com/stats/maps-no_clusters/www.openwetware.org-wiki-Kim-thumb.jpg



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