Kim

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Overview Our research spans the disciplinary boundaries between nanotechnology, biomaterials, and mechanobiology with an emphasis on their applications to tissue engineering and regenerative medicine. Through the use of multi-scale (nano/micro/meso) fabrication and integration tools, we focus on the development and application of bio-inspired materials/devices and functional tissue engineering models for elucidating regenerative biology, drug screening, disease modeling, and stem cell-based therapies. Using engineered microenvironments in combination with quantitative live cell imaging approaches, we are also studying the intricate interactions between mechanical and biochemical signaling in the regulation of cell/tissue function and fate decisions that are essential for tumor progression and metastasis, tissue repair and regeneration following injury, and various developmental events. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multi-scale regenerative technologies for improving human health.

News Prof. Kim has been promoted to Associate Professor with Tenure! (06/2017) Kim lab has been awarded a NIH R01 grant! (02/2017) Peter Kim has been awarded the AHA Predoctoral Fellowship! (12/2014) Cameron Nemeth has been given a BMES Undergraduate Design and Research Award and the Washington Research Foundation Fellowship. (Sept. 2013) Read more Prof. Kim has been awarded the prestigious Young Investigator Award 2013 from the Korean-American Scientists and Engineers Association (KSEA). (06/2013) Prof. Kim joined the editorial board of the Journal of Biomedical Nanotechnology as an Associate Editor. (05/ 2013) Kim Lab has been awarded an Muscular Dystrophy Association (MDA) research grant to develop bioengineering techniques for growing muscle for use in transplantation into a mouse model of Duchenne muscular dystrophy. (02/2013)

Featured Publications Thermoresponsive nanofabricated substratum for the engineering of three-dimensional tissues with layer-by-layer architectural control, ACS Nano, vol. 8, pp. 4430-4439, 2014. Article Nanopatterned muscle cell patches for enhanced myogenesis and dystrophin expression in a mouse model of muscular dystrophy, Biomaterials, vol. 35, pp. 1478-1486, 2014. Article Nanotopography-guided tissue engineering and regenerative medicine, Advanced Drug Delivery Review, vol. 65, pp. 536-558, 2013. (Featured as a Cover Article) Article Nanopatterned cardiac cell patches promote stem cell niche formation and myocardial regeneration, Integrative Biology, Vol. 4, Issue 9,pp. 1019-1033, 2012 (Featured as a Cover Article) Article Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors, Science Signaling, vol. 5, issue 227, p. ra41, 2012. (Featured as a Cover Article) Article Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs, Proceedings of National Academy of Sciences USA, vol.107, pp. 565-570, 2010. Article (Highlighted in the National Institute of Biomedical Imaging and Bioengineering) Microengineered platforms for cell mechanobiology, Annual Review of Biomedical Engineering, vol. 11, pp.203-233, 2009. Article

[| University of Washington ]      [| College of Engineering ]      [| UW Medicine ]      [| UW Bioengineering ]     

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