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Revision as of 13:03, 10 September 2010

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Welcome to the D.H. Kim Lab

Our research spans the disciplinary boundaries between biomechanics, nanobiotechnology, and cell biology with an emphasis on their applications to tissue engineering and regenerative medicine. We focuses on the development and applications of biomimetic cell culture models and tissue engineering constructs for studying the intricate interactions between mechanical and biochemical signaling in cell/tissue function and fate decisions that are essential for cancer metastasis, tissue repair and regeneration following injury, and various developmental events. Using BioMEMS and nanotechnology-based tools, we would like to also bridge the gap between understanding structure-function relationships at molecular and cellular levels, and being able to utilize bioinspired tissue engineering models for drug discovery, stem cell-based therapies, disease diagnostics, and medical device development. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multiscale regenerative technologies for improving human health.


News

Publications

  • D.H. Kim*, H.J. Lee*, Y.K. Lee, J.M. Nam, and A. Levchenko, "Biomimetic nanopatterns as enabling tools for analysis and control of live cells," Advanced Materials, 2010. Pubmed, Hubmed
  • K. Gupta*, D.H. Kim*, D. Ellison, C. Smith, A. Kundu, K.Y. Suh, J. Tuan, and A. Levchenko, “Lab-on-a-chip devices as an emerging platform for stem cell biology,” Lab on a Chip, vol. 10, pp.2019-2031, 2010. Pubmed, Hubmed
  • M.H. You, M.K. Kwak, D.H. Kim, K. Kim, A. Levchenko, D.Y. Kim, and K.Y. Suh, “Synergistically enhanced osteogenic differentiation of human mesenchymal stem cells by culture on nanostructured surfaces with induction media,” Biomacromolecules, vol. 11, pp.1856-1862, 2010. Pubmed, Hubmed



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