Kim

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<h3>Featured Publications</h3>  
<h3>Featured Publications</h3>  
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*Kshitiz, et al. “Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors,” '''Science Signaling''' Vol. 5, Issue. 227, ra41, 2012. [http://stke.sciencemag.org/content/vol5/issue227/cover.dtl '''(Featured as a Cover Article)''']  [http://stke.sciencemag.org/cgi/content/abstract/sigtrans;5/227/ra41 Article]
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*Kshitiz, et al. “Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors,” Science Signaling, Vol. 5, Issue. 227, ra41, 2012. [http://stke.sciencemag.org/content/vol5/issue227/cover.dtl '''(Featured as a Cover Article)''']  [http://stke.sciencemag.org/cgi/content/abstract/sigtrans;5/227/ra41 Article]
*Engineering neuronal growth cone to promote axon regeneration over inhibitory molecules, Proceedings of the National Academy of Sciences USA, vol. 108, pp. 5057-5062, 2011. [http://www.pnas.org/content/early/2011/03/03/1011258108.full.pdf+html Article]<BR>
*Engineering neuronal growth cone to promote axon regeneration over inhibitory molecules, Proceedings of the National Academy of Sciences USA, vol. 108, pp. 5057-5062, 2011. [http://www.pnas.org/content/early/2011/03/03/1011258108.full.pdf+html Article]<BR>
* Biomimetic nanopatterns as enabling tools for analysis and control of live cells, Advanced Materials, 2010. [http://www.ncbi.nlm.nih.gov/pubmed/20803528 Pubmed], [http://www.hubmed.org/display.cgi?uids=20803528 Hubmed] <BR>
* Biomimetic nanopatterns as enabling tools for analysis and control of live cells, Advanced Materials, 2010. [http://www.ncbi.nlm.nih.gov/pubmed/20803528 Pubmed], [http://www.hubmed.org/display.cgi?uids=20803528 Hubmed] <BR>

Revision as of 20:37, 6 June 2012

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Overview

Our research spans the disciplinary boundaries between biomaterials, nanotechnology, and cell mechanobiology with an emphasis on their applications to tissue engineering and regenerative medicine. Through the use of multiscale fabrication and integration tools, we focus on the development and applications of biomimetic cell culture models and functional tissue engineering constructs for high-throughput drug screening, stem cell-based therapies, disease diagnostics, and medical device development. Using engineered microenvironments in combination with live cell imaging approaches, we are also studying the interplay between mechanical and biochemical signaling in the regulation of cell function and fate decisions that are essential for tissue repair and regeneration following injury, and various developmental events. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multiscale regenerative technologies for improving human health.

News

  • D. Kim appointed as program committee member of IEEE International Conference on Nano/Molecular Medicine and Engineering (2012)
  • D. Kim co-organized the first USACM Thematic Conference on Multiscale Methods and Validation in Medicine and Biology: Biomechanics and Mechanobiology (Jan, 2012)
  • D. Kim gave an invited talk at the 5th International Conference on Cell Therapy, Seoul, Korea (Nov. 2011)
  • D. Kim gave an invited talk at the 10th International Conference on Nanoimprint and Nanoprint Technology (Oct, 2011)


Featured Publications

  • Kshitiz, et al. “Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors,” Science Signaling, Vol. 5, Issue. 227, ra41, 2012. (Featured as a Cover Article) Article
  • Engineering neuronal growth cone to promote axon regeneration over inhibitory molecules, Proceedings of the National Academy of Sciences USA, vol. 108, pp. 5057-5062, 2011. Article
  • Biomimetic nanopatterns as enabling tools for analysis and control of live cells, Advanced Materials, 2010. Pubmed, Hubmed
  • Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs, Proceedings of National Academy of Sciences USA, vol.107, pp. 565-570, 2010. Pubmed, Hubmed
  • Microengineered platform for cell mechanobiology, Annual Review of Biomedical Engineering, vol. 11, pp.203-233, 2009. Pubmed

[| University of Washington ]      [| College of Engineering ]      [| UW Medicine ]      [| UW Bioengineering ]     

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