Overview
Our research spans the disciplinary boundaries between biomaterials, nanotechnology, and cell mechanobiology with an emphasis on their applications to tissue engineering and regenerative medicine. Through the use of multiscale fabrication and integration tools, we focus on the development and applications of biomimetic cell culture models and functional tissue engineering constructs for high-throughput drug screening, stem cell-based therapies, disease diagnostics, and medical device development. Using engineered microenvironments in combination with live cell imaging approaches, we are also studying the interplay between mechanical and biochemical signaling in the regulation of cell function and fate decisions that are essential for tissue repair and regeneration following injury, and various developmental events. The ultimate goal of our research is to better understand complex cellular behavior in response to microenvironmental cues in normal, aging and disease states, to gain new mechanistic insights into the control of cell-tissue structure and function, and to develop multiscale regenerative technologies for improving human health.
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News
- Professor Kim participated as a Program committee member in IEEE International Conference on Nano/Molecular Medicine and Engineering (2012)
- Professor Kim participated the first USACM Thematic Conference on Multiscale Methods and Validation in Medicine and Biology: Biomechanics and Mechanobiology as a Organizing committee member (2012)
- Professor Kim take a part in “Reprogramming and Stem Cell Therapy” session at the 5th International Conference on Cell Therapy, Seoul, Korea as a Session Chair (11/01/2011)
- Professor Kim was a Session Chair of “Biology/micro-TAS, Biomimetics, Self-assembly, Chemistry” session at the 10th International Conference on Nanoimprint and Nanoprint Technology, JeJu, Korea (10/19-21/2011)
- Professor Kim take a role as a Co-guest editor for IET Micro and Nano Letters: special issue on micro-nanoengineered platforms for mechanobiology studies (2011)
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Recent Publications
- Engineering neuronal growth cone to promote axon regeneration over inhibitory molecules, Proceedings of the National Academy of Sciences USA, vol. 108, pp. 5057-5062, 2011. Article
- Biomimetic nanopatterns as enabling tools for analysis and control of live cells, Advanced Materials, 2010. Pubmed, Hubmed
- Nanoscale cues regulate the structure and function of macroscopic cardiac tissue constructs, Proceedings of National Academy of Sciences USA, vol.107, pp. 565-570, 2010. Pubmed, Hubmed
- Microengineered platform for cell mechanobiology, Annual Review of Biomedical Engineering, vol. 11, pp.203-233, 2009. Pubmed
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