Klinke:Publications: Difference between revisions
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# '''Klinke, D. J.'''; “An Empirical Bayesian Approach for Model-based Inference of Cellular Signaling Networks", ''BMC Bioinformatics'' in press (2009). | # '''Klinke, D. J.'''; “An Empirical Bayesian Approach for Model-based Inference of Cellular Signaling Networks", ''BMC Bioinformatics'' in press (2009). | ||
# '''Klinke, D. J.'''; “Validating a Dimensionless Number for Glucose Homeostasis in Humans", ''Ann. Biomed. Eng.'' in press (2009). | # '''Klinke, D. J.'''; “Validating a Dimensionless Number for Glucose Homeostasis in Humans", ''Ann. Biomed. Eng.'' in press (2009). | ||
// Develops and validates a dimensionless number for the ratio of insulin production and insulin-dependent glucose metabolism in humans. | |||
# '''Klinke, D. J.*'''; Brundage, K; “Scalable Analysis of Flow Cytometry Data using R/Bioconductor", ''Cytometry A'' 75A:699-706 (2009). *corresponding author | # '''Klinke, D. J.*'''; Brundage, K; “Scalable Analysis of Flow Cytometry Data using R/Bioconductor", ''Cytometry A'' 75A:699-706 (2009). *corresponding author | ||
// Provides a tutorial for using R/Bioconductor to process flow cytometry data. | |||
# '''Klinke, D. J.'''; “Extent of Beta Cell Destruction is Important but Insufficient to Predict the Onset of Type 1 Diabetes Mellitus”, ''PLoS ONE'' 3:e1374 (2008). | # '''Klinke, D. J.'''; “Extent of Beta Cell Destruction is Important but Insufficient to Predict the Onset of Type 1 Diabetes Mellitus”, ''PLoS ONE'' 3:e1374 (2008). | ||
// Evaluates the conventional wisdom regarding the extent of beta cell destruction required before presenting with symptoms of type 1 diabetes. | |||
# '''Klinke, D. J.*'''; Ustyugova, I. V.; Brundage, K.; Barnett, J. B.; “Modulating Temporal Control of NF-kappaB Activation: Implications for Therapeutic and Assay Selection”, ''Biophysical J.'' 94:4249-4259 (2008). *corresponding author | # '''Klinke, D. J.*'''; Ustyugova, I. V.; Brundage, K.; Barnett, J. B.; “Modulating Temporal Control of NF-kappaB Activation: Implications for Therapeutic and Assay Selection”, ''Biophysical J.'' 94:4249-4259 (2008). *corresponding author | ||
// Finds that our ability to observe significant biological events is limited by the signal-to-noise characteristics of the assays that we use to observe cellular responses. | |||
# '''Klinke, D. J.'''; “Integrating Epidemiological Data into a Mechanistic Model of Type 2 Diabetes: Validating the Prevalence of Virtual Patients”, ''Ann. Biomed. Eng.'' 36:321-334 (2008). | # '''Klinke, D. J.'''; “Integrating Epidemiological Data into a Mechanistic Model of Type 2 Diabetes: Validating the Prevalence of Virtual Patients”, ''Ann. Biomed. Eng.'' 36:321-334 (2008). | ||
// Provides a glimpse of the kind of models developed by [http://www.entelos.com/ Entelos, Inc.] | |||
# '''Klinke, D.J.'''; “A Multi-scale Model of Dendritic Cell Education and Trafficking in the Lung: Implications for T Cell Polarization”, ''Ann. Biomed. Eng.'' 35:937-955 (2007). | # '''Klinke, D.J.'''; “A Multi-scale Model of Dendritic Cell Education and Trafficking in the Lung: Implications for T Cell Polarization”, ''Ann. Biomed. Eng.'' 35:937-955 (2007). | ||
# '''Klinke, D.J.'''; “An Age-Structured Model of Dendritic Cell Trafficking in the Lung”, ''Am. J. Physiol. Lung Cell. Mol. Physiol.'' 291:L1038-L1049 (2006). | # '''Klinke, D.J.'''; “An Age-Structured Model of Dendritic Cell Trafficking in the Lung”, ''Am. J. Physiol. Lung Cell. Mol. Physiol.'' 291:L1038-L1049 (2006). | ||
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# '''Klinke, D. J.'''; Dooling, D. J.; and Broadbelt, L. J.; "A Theoretical Study of Methylidyne Chemisorption on Ni(111) and Co(0001) Surfaces"; ''Surf. Sci.'' 425:334-342 (1999). | # '''Klinke, D. J.'''; Dooling, D. J.; and Broadbelt, L. J.; "A Theoretical Study of Methylidyne Chemisorption on Ni(111) and Co(0001) Surfaces"; ''Surf. Sci.'' 425:334-342 (1999). | ||
# '''Klinke, D. J.''' and Broadbelt, L. J., "Construction of a Mechanistic Model of Fischer-Tropsch Synthesis on Ni(111) and Co(0001) Surfaces", ''Chem. Eng. Sci.'' 54:3379-3389 (1999). | # '''Klinke, D. J.''' and Broadbelt, L. J., "Construction of a Mechanistic Model of Fischer-Tropsch Synthesis on Ni(111) and Co(0001) Surfaces", ''Chem. Eng. Sci.'' 54:3379-3389 (1999). | ||
// The first application of an automatic reaction network generation algorithm to catalytic chemistry. | |||
# '''Klinke, D. J.'''; Wilke, S.; and Broadbelt, L. J.; "A Theoretical Study of Carbon Chemisorption on Ni(111) and Co(0001) Surfaces", ''J. Catal.'' 178:540-554 (1998). | # '''Klinke, D. J.'''; Wilke, S.; and Broadbelt, L. J.; "A Theoretical Study of Carbon Chemisorption on Ni(111) and Co(0001) Surfaces", ''J. Catal.'' 178:540-554 (1998). | ||
# '''Klinke, D. J.''' and Broadbelt, L. J., "Mechanism Reduction during Computer Generation of Compact Reaction Models", ''AIChE J.'' 43:1828-1837 (1997). | # '''Klinke, D. J.''' and Broadbelt, L. J., "Mechanism Reduction during Computer Generation of Compact Reaction Models", ''AIChE J.'' 43:1828-1837 (1997). | ||
pmid=19513847 | |||
pmid=18281385 | |||
pmid=18167535 | |||
pmid=18046647 | |||
=== [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=PureSearch&db=pubmed&details_term=Klinke%20DJ%5Bau%5D%20 Link to PubMed citations] === | === [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=PureSearch&db=pubmed&details_term=Klinke%20DJ%5Bau%5D%20 Link to PubMed citations] === | ||
<br> | <br> |
Revision as of 19:09, 12 October 2009
Publications
- Leski, T. A.; Caswell, C. C.; Pawlowski, M.; Klinke, D. J.; Bujnicki, M.; Hart, S. J.; Lukomski, S.; “bcl- Genes of Bacillus cereus Group Organisms: Identification, Classification and Application in Anthrax Detection and Fingerprinting", Appl Environ Microbiol in press (2009).
- Klinke, D. J.; “An Empirical Bayesian Approach for Model-based Inference of Cellular Signaling Networks", BMC Bioinformatics in press (2009).
- Klinke, D. J.; “Validating a Dimensionless Number for Glucose Homeostasis in Humans", Ann. Biomed. Eng. in press (2009).
// Develops and validates a dimensionless number for the ratio of insulin production and insulin-dependent glucose metabolism in humans.
- Klinke, D. J.*; Brundage, K; “Scalable Analysis of Flow Cytometry Data using R/Bioconductor", Cytometry A 75A:699-706 (2009). *corresponding author
// Provides a tutorial for using R/Bioconductor to process flow cytometry data.
- Klinke, D. J.; “Extent of Beta Cell Destruction is Important but Insufficient to Predict the Onset of Type 1 Diabetes Mellitus”, PLoS ONE 3:e1374 (2008).
// Evaluates the conventional wisdom regarding the extent of beta cell destruction required before presenting with symptoms of type 1 diabetes.
- Klinke, D. J.*; Ustyugova, I. V.; Brundage, K.; Barnett, J. B.; “Modulating Temporal Control of NF-kappaB Activation: Implications for Therapeutic and Assay Selection”, Biophysical J. 94:4249-4259 (2008). *corresponding author
// Finds that our ability to observe significant biological events is limited by the signal-to-noise characteristics of the assays that we use to observe cellular responses.
- Klinke, D. J.; “Integrating Epidemiological Data into a Mechanistic Model of Type 2 Diabetes: Validating the Prevalence of Virtual Patients”, Ann. Biomed. Eng. 36:321-334 (2008).
// Provides a glimpse of the kind of models developed by Entelos, Inc.
- Klinke, D.J.; “A Multi-scale Model of Dendritic Cell Education and Trafficking in the Lung: Implications for T Cell Polarization”, Ann. Biomed. Eng. 35:937-955 (2007).
- Klinke, D.J.; “An Age-Structured Model of Dendritic Cell Trafficking in the Lung”, Am. J. Physiol. Lung Cell. Mol. Physiol. 291:L1038-L1049 (2006).
- Klinke, D.J.; “The Ratio of P40 Monomer to Dimer is an Important Determinant of IL-12 Bioactivity”, J. Theor. Bio. 240:323-335 (2006).
- Broadbelt, L. J. and Klinke, D. J., "Kinetics of Catalyzed Reactions – D (Heterogeneous)" in Encyclopedia of Catalysis, Istvan T. Horvath (Editor-in-Chief), ISBN 0-471-24183-0, pp. 4772, December 2002.
- Klinke, D. J. and Broadbelt, L. J., "A Theoretical Study of Hydrogen Chemisorption on Ni(111) and Co(0001) Surfaces", Surf. Sci. 429:169-177 (1999).
- Klinke, D. J.; Dooling, D. J.; and Broadbelt, L. J.; "A Theoretical Study of Methylidyne Chemisorption on Ni(111) and Co(0001) Surfaces"; Surf. Sci. 425:334-342 (1999).
- Klinke, D. J. and Broadbelt, L. J., "Construction of a Mechanistic Model of Fischer-Tropsch Synthesis on Ni(111) and Co(0001) Surfaces", Chem. Eng. Sci. 54:3379-3389 (1999).
// The first application of an automatic reaction network generation algorithm to catalytic chemistry.
- Klinke, D. J.; Wilke, S.; and Broadbelt, L. J.; "A Theoretical Study of Carbon Chemisorption on Ni(111) and Co(0001) Surfaces", J. Catal. 178:540-554 (1998).
- Klinke, D. J. and Broadbelt, L. J., "Mechanism Reduction during Computer Generation of Compact Reaction Models", AIChE J. 43:1828-1837 (1997).
pmid=19513847 pmid=18281385 pmid=18167535 pmid=18046647
Link to PubMed citations