Penn State Department of Chemical Engineering Seminar Series:
A Bayesian Perspective on Understanding How Cells Make Decisions
This Week in WV - Mountain State Science - WV Public Broadcasting:
Reporter Ben Adducchio talks with Dr. Klinke about nanoscience and his work in cancer immunology. In this brief segment, Dr. Klinke refers to nanoscale structures, called exosomes, that are thought to play key roles in intercellular communication - such as between cancer and immune cells. Exosomes are 50 - 100 nm in diameter membrane vesicles that contain transmembrane proteins embedded within a lipid bilayer, cytosolic proteins and, potentially, microRNAs derived from donor cells. Understanding the role of these naturally designed nanoscale structures in facilitating cell-to-cell communication will ultimately aid in engineering nanoscale structures as immunotherapies.