Koop:Mdwilson: Difference between revisions
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I am a research associate in the [[koop|Koop lab]] in the [http://web.uvic.ca/cbr/ Centre for Biomedical Research] at [http://www.uvic.ca University of Victoria]. | I am a research associate in the [[koop|Koop lab]] in the [http://web.uvic.ca/cbr/ Centre for Biomedical Research] at [http://www.uvic.ca University of Victoria]. My main interests are in studying the evolution and uncovering the function of novel genes associated with fertilization, the immune system and human disease. | ||
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***7q22 Acute myeloid leukemia | ***7q22 Acute myeloid leukemia | ||
***Paired immunoglobulin like receptors | ***Paired immunoglobulin like receptors | ||
*Using mouse genetics and embryonic stem cells to investigate the function of novel genes | **Using mouse genetics and embryonic stem cells to investigate the function of novel genes | ||
***Zonadhesin -- Zonadhesin is a novel gene that is under positive selection and is hypothesized to play a role in the species specific recognition of sperm and egg in mammals | ***Zonadhesin -- Zonadhesin is a novel gene that is under positive selection and is hypothesized to play a role in the species specific recognition of sperm and egg in mammals | ||
***Ars2 -- Ars2 was first discovered by others as a gene that conferred arsenite resistance to an arsenite sensitive cell line. We characterized this gene in humans and mice and are currently studying the phenotype of Ars2 mutants. Ars2 orthologs are found in all characterized eukaryotic genomes with the notable exception of '''S. cerevisiae'''. | |||
***Ars2 -- Ars2 was first discovered by others as a gene that conferred arsenite resistance to an arsenite sensitive cell line. We characterized this gene in humans and mice and are currently studying the phenotype of Ars2 mutants. Ars2 orthologs are found in all characterized eukaryotic genomes with the notable exception of '''S. cerevisiae'''. | |||
***Gnrhr -- This is a collaboration with Dr. Nancy Sherwood and Sheng Wu. | ***Gnrhr -- This is a collaboration with Dr. Nancy Sherwood and Sheng Wu. | ||
***Achi -- A novel gene embedded in Ache (more information coming soon). | |||
</blockquote> | </blockquote> | ||
Revision as of 23:25, 19 October 2006
Michael Wilson Centre for Biomedical Research |
I am a research associate in the Koop lab in the Centre for Biomedical Research at University of Victoria. My main interests are in studying the evolution and uncovering the function of novel genes associated with fertilization, the immune system and human disease.
Current Research Interests
- Comparative genomics and evolution
- Chromsome seven regions associated with duplications, deletions and disease
- 7q11 William-Beuron syndrome
- 7q22 Acute myeloid leukemia
- Paired immunoglobulin like receptors
- Using mouse genetics and embryonic stem cells to investigate the function of novel genes
- Zonadhesin -- Zonadhesin is a novel gene that is under positive selection and is hypothesized to play a role in the species specific recognition of sperm and egg in mammals
- Ars2 -- Ars2 was first discovered by others as a gene that conferred arsenite resistance to an arsenite sensitive cell line. We characterized this gene in humans and mice and are currently studying the phenotype of Ars2 mutants. Ars2 orthologs are found in all characterized eukaryotic genomes with the notable exception of S. cerevisiae.
- Gnrhr -- This is a collaboration with Dr. Nancy Sherwood and Sheng Wu.
- Achi -- A novel gene embedded in Ache (more information coming soon).
Education
PhD, University of Victoria, September 2005
My undergraduate degree was in Biochemistry and Hispanic studies at the University of Victoria.