Koop:Mdwilson: Difference between revisions
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== Education== | == Education== | ||
<blockquote>PhD, University of Victoria, October 2005 <br> | <blockquote>PhD, University of Victoria, October 2005 <br> | ||
My undergraduate degree was in Biochemistry and Hispanic studies | B.Sc., University of Victoria. My undergraduate degree was in Biochemistry and Hispanic studies. | ||
<br> | <br> | ||
</blockquote> | </blockquote> |
Revision as of 23:46, 19 February 2007
Michael Wilson Centre for Biomedical Research |
I am a research associate in the Koop lab in the Centre for Biomedical Research at University of Victoria. My main interests are in studying the evolution and uncovering the function of novel genes associated with fertilization, development, the immune system and human disease.
Research Interests
Comparative genomics and evolution
- Genomics regions associated with duplications, insertions, deletions and disease
- 7q11 William-Beuren syndrome
- 7q22 Acute myeloid leukemia
- Paired immunoglobulin like receptors
- Segmental duplications
- Alternative splicing
Using mouse genetics and embryonic stem cells to investigate the function of novel genes
- Zonadhesin -- Zonadhesin is a novel gene that is under positive selection and is hypothesized to play a role in the species specific recognition of sperm and egg in mammals (In collaboration with Daniel Hardy and Andras Nagy)
- Ars2 -- Ars2 was first discovered by others as a gene that conferred arsenite resistance to an arsenite sensitive cell line. We characterized this gene in humans and mice and are currently studying the phenotype of Ars2 mutants. Ars2 orthologs are found in all characterized eukaryotic genomes with the notable exception of S. cerevisiae. This is in collaboration with Andras Nagy, Perry Howard, Robert Burke and Diana Wang.
- Gnrhr -- This is a collaboration with Dr. Nancy Sherwood and Sheng Wu.
- Achi -- A novel gene embedded in Ache (In collaboration with Corrinne Lobe, more information coming soon).
Education
PhD, University of Victoria, October 2005
B.Sc., University of Victoria. My undergraduate degree was in Biochemistry and Hispanic studies.