Kreitman - Revision history

Bin He: /* News */

2013-05-23T05:47:20Z

News

←Older revision		Revision as of 05:47, 23 May 2013
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	==News==		==News==
		+	===May 2013===
		+	After a lot of back and forth revision, our twin papers on the fly model of human misfolded insulin are officially submitted to the journal Genetics. While they are still under review, we'll post them onto arXiv and will post links here shortly.
		+
		+	* S-Y Park, M.Z. Ludwig, N. Tamarina, et al. Genetic Complexity in a Drosophila Model of Diabetes-Associated Misfolded Human Proinsulin.
		+	* He, B.Z., Ludwig, M.Z., D.A. Dickerson, et al. Effect of Genetic Variation in a Drosophila Model of Diabetes-Associated Misfolded Human Proinsulin.
		+
	===December 2012===		===December 2012===
	[[Image:P1020523.JPG\|left\|400px]]		[[Image:P1020523.JPG\|left\|400px]]

Bin He: /* December 2012 */

2013-01-27T18:37:16Z

December 2012

←Older revision		Revision as of 18:37, 27 January 2013
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	===December 2012===		===December 2012===
	[[Image:P1020523.JPG\|left\|400px]]		[[Image:P1020523.JPG\|left\|400px]]
-	Misha ~~Marty~~ Bin	+	Misha Bin Marty
	{{-}}		{{-}}

Bin He: /* December 2012 */

2013-01-27T18:36:53Z

December 2012

←Older revision		Revision as of 18:36, 27 January 2013
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	==News==		==News==
	===December 2012===		===December 2012===
-	[[Image:P1020523.JPG\|left\|~~600px~~]]	+	[[Image:P1020523.JPG\|left\|400px]]
	Misha Marty Bin		Misha Marty Bin
	{{-}}		{{-}}

Martin Kreitman at 20:58, 11 January 2013

2013-01-11T20:58:40Z

←Older revision		Revision as of 20:58, 11 January 2013
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	==News==		==News==
		+	===December 2012===
		+	[[Image:P1020523.JPG\|left\|600px]]
		+	Misha Marty Bin
		+	{{-}}
		+
	===October 2012===		===October 2012===
	Bin has successfully defended his doctoral thesis and in December he will officially graduate! He is going to join Erin O'Shea group in Harvard and HHMI.		Bin has successfully defended his doctoral thesis and in December he will officially graduate! He is going to join Erin O'Shea group in Harvard and HHMI.

Bin He: /* News */

2012-12-24T01:49:17Z

News

←Older revision		Revision as of 01:49, 24 December 2012
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	==News==		==News==
		+	===October 2012===
		+	Bin has successfully defended his doctoral thesis and in December he will officially graduate! He is going to join Erin O'Shea group in Harvard and HHMI.
		+
		+	Can't believe that it has been a year since our last update. But be assured that we are not idling. Rather, two manuscripts are being cooked and hopefully we'll be able to get them out of the door early in the new year!
		+
	===October 2011===		===October 2011===
	Misha and Manu have joint force (developmental biology + live imaging + quantitative image analysis) to tackle the question "is there a boundary to transcriptional enhancers?" Enhancers were identified as the minimal piece of sequence that can reproduce the endorgenous expression pattern and for historical reasons, their physical boundaries were "defined" by the restriction enzyme cutting site or pcr primer locations, both of which used by researchers to test difference pieces. Later people have found additional transcription factor binding sites outside these "minimal elements". They are not essential for "producing the expression pattern" in a reporter assay, which is qualitative and doesn't examine the fitness results. Do those additional binding sites matter? How? Check out here: [http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1002364 PLoS Genetics]		Misha and Manu have joint force (developmental biology + live imaging + quantitative image analysis) to tackle the question "is there a boundary to transcriptional enhancers?" Enhancers were identified as the minimal piece of sequence that can reproduce the endorgenous expression pattern and for historical reasons, their physical boundaries were "defined" by the restriction enzyme cutting site or pcr primer locations, both of which used by researchers to test difference pieces. Later people have found additional transcription factor binding sites outside these "minimal elements". They are not essential for "producing the expression pattern" in a reporter assay, which is qualitative and doesn't examine the fitness results. Do those additional binding sites matter? How? Check out here: [http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1002364 PLoS Genetics]

Bin He: /* The Kreinitz lab at large in 2012 spring */

2012-05-19T01:54:27Z

The Kreinitz lab at large in 2012 spring

←Older revision		Revision as of 01:54, 19 May 2012
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	=== The Kreinitz lab at large in 2012 spring ===		=== The Kreinitz lab at large in 2012 spring ===
	[[Image:Kreinitz lab 2012 numbered.png\|link=people\|left\|600px\|Kreinitz lab 2012 spring]]		[[Image:Kreinitz lab 2012 numbered.png\|link=people\|left\|600px\|Kreinitz lab 2012 spring]]
-	1. Pengyao Jiang 2. Qian Zang 3. UnJin Lee 4. Manu 5. Jackie Gavin-Smyth 6. Ah-Ram Kim 7. David Gittin 8. Zhihao Lou 9. John Reinitz 10. Bin He 11. Aashish Jha 12. Carlos Martinez 13. Kenneth Bar 14. Marty Kreitman 15. Lena Panok 16 (not in picture...) Misha Ludwig (we should PS you in!)	+	Click on image to see names of people
	{{-}}		{{-}}

Bin He: /* The Kreinitz lab at large in 2012 spring */

2012-05-19T01:53:57Z

The Kreinitz lab at large in 2012 spring

←Older revision		Revision as of 01:53, 19 May 2012
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	==Group Pictures==		==Group Pictures==
	=== The Kreinitz lab at large in 2012 spring ===		=== The Kreinitz lab at large in 2012 spring ===
-	~~<imagemap>~~	+	[[Image:Kreinitz lab 2012 numbered.png\|link=people\|left\|600px\|Kreinitz lab 2012 spring]]
-	Image:Kreinitz lab 2012.png\|left\|600px\|~~alt=~~Kreinitz lab 2012 spring	+	1. Pengyao Jiang 2. Qian Zang 3. UnJin Lee 4. Manu 5. Jackie Gavin-Smyth 6. Ah-Ram Kim 7. David Gittin 8. Zhihao Lou 9. John Reinitz 10. Bin He 11. Aashish Jha 12. Carlos Martinez 13. Kenneth Bar 14. Marty Kreitman 15. Lena Panok 16 (not in picture...) Misha Ludwig (we should PS you in!)
-	~~default [[~~	+
-	~~</imagemap>~~	+
	{{-}}		{{-}}

Bin He: /* The Kreinitz lab at large in 2012 spring */

2012-05-19T01:38:04Z

The Kreinitz lab at large in 2012 spring

←Older revision		Revision as of 01:38, 19 May 2012
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	==Group Pictures==		==Group Pictures==
	=== The Kreinitz lab at large in 2012 spring ===		=== The Kreinitz lab at large in 2012 spring ===
-	[[Image:Kreinitz lab 2012.png\|left\|600px]]	+	<imagemap>
-	~~Manu, Bin, Anna, Cecelia, Sara, Marty, Jason (from left to right)~~	+	Image:Kreinitz lab 2012.png\|left\|600px\|alt=Kreinitz lab 2012 spring
		+	default [[
		+	</imagemap>
	{{-}}		{{-}}

Bin He: /* Kreitman lab as of 2009 summer */

2012-05-18T14:07:02Z

Kreitman lab as of 2009 summer

←Older revision		Revision as of 14:07, 18 May 2012
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	=== Kreitman lab as of 2009 summer ===		=== Kreitman lab as of 2009 summer ===
	[[Image:Group_pic_2009.JPG\|left\|600px]]		[[Image:Group_pic_2009.JPG\|left\|600px]]
-	Manu, Bin, Anna, Cecelia, Sara, Marty, Jason (from left to right)	+	Manu, Bin, Anna, Cecelia, Sara, Marty, Jason (from left to right)
	{{-}}		{{-}}

Bin He: /* Group Pictures */

2012-05-18T14:06:51Z

Group Pictures

←Older revision		Revision as of 14:06, 18 May 2012
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	[[Image:Kreinitz lab 2012.png\|left\|600px]]		[[Image:Kreinitz lab 2012.png\|left\|600px]]
	Manu, Bin, Anna, Cecelia, Sara, Marty, Jason (from left to right)		Manu, Bin, Anna, Cecelia, Sara, Marty, Jason (from left to right)
		+	{{-}}

	=== Kreitman lab as of 2009 summer ===		=== Kreitman lab as of 2009 summer ===
	[[Image:Group_pic_2009.JPG\|left\|600px]]		[[Image:Group_pic_2009.JPG\|left\|600px]]
	Manu, Bin, Anna, Cecelia, Sara, Marty, Jason (from left to right)		Manu, Bin, Anna, Cecelia, Sara, Marty, Jason (from left to right)
		+	{{-}}