LabName:Alcazar

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This webpage will be discontinued soon. A new webpage is hosted at the UB servers:
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Please visit: http://www.ub.edu/portal/web/dp-bsma/stress
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'''''Dear visitor,'''''<br>
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<br> Welcome to the Molecular Genetics of Plant Stress Tolerance Lab (Ruben Alcazar & A.F. Tiburcio Labs) ''' at the Department of Biology, Healthcare & Environment of the University of Barcelona. <br><br>
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We're a recently created joint research group that investigates the '''adaptation of plants to local environments'''. We focus on the evolutionary adaptation of plant populations to '''abiotic and biotic stresses''', which are major challenges for plant survival under the current climate change predictions. Derived from our research, we investigate ways for improving stress protection.<br>
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For a more detailed view of our research, please have a look at our [http://alcazar.openwetware.org/Research.html Research Projects] and [http://alcazar.openwetware.org/Publications.html Scientific Publications] sections. You can follow an updated list of our activities and publications in the NEWS section below. For any other enquires, do not hesitate to contact us directly.<br><br>
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'''''Plant-Environment Interactions'''''<br><br>
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'''1. POLYAMINE PERCEPTION AND SIGNALING'''
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'''Advance in Knowledge. '''
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We're interested in genetics of natural variation, population genetics and molecular biology. We're currently studying immune receptor gene variation and its involvement in the evolvement of incompatibilities between wild populations, from a molecular and evolutionary perspective.  <br><br>  
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Our research laboratory has long-standing experience in the field of plant polyamines, for which we performed a number of omics approaches and established genetic evidence for their role in abiotic stress protection.  
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'''Applied research. '''
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Our lab is also associated with the group of A.F.Tiburcio to study polyamine homeostasis in plants and its practical applications on inducing stress tolerance. <br><br>
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'''Dissemination of Knowledge. '''
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For a more detailed view of our research, have a look at our [http://alcazar.openwetware.org/Research.html Research Projects] and [http://alcazar.openwetware.org/Publications.html Scientific Publications] sections. For general public information have a look at [http://alcazar.openwetware.org/Alcazar_Youtube.html +info]. <br><br>
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'''University. ''' Transferring knowledge to future generations. We participate in different university academic activities summarized in [http://alcazar.openwetware.org/Lectures.html Teaching activities]. <br>
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<br><br>
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Our previous research pointed to interactions of polyamines with hormones and other stress-related metabolites. Our current goal is to investigate how polyamines are perceived by the plant, which early signaling components are involved, and how this is shaped by the environment.
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We’re making use of background knowledge from different disciplines to gain insight into polyamine perception and signaling, for which little is known in plants. We’re making use of genetics of natural variation, reverse genetics, molecular biology and plant-microbe interactions to unravel how polyamines are sensed and how this relates to the local microbiota.
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Our final goal is to provide novel approaches for crop protection against abiotic and biotic stresses.
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Key words: stress tolerance, drought, salinity, freezing tolerance, priming, ROS, crop protection, microbiome, rhizosphere, polyamines, natural variation, transcriptional regulation, metabolon, modulon.
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'''2. MOLECULAR EVOLUTION OF DISEASE RESISTANCE IN PLANTS''' <br>
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In our lab, we make use of the extensive natural variation of [https://en.wikipedia.org/wiki/Arabidopsis_thaliana ''Arabidopsis thaliana''] populations to answer key fundamental questions:
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* '''How plants adapt to local environments including the microbiota?'''
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[[Image:Announcement_alcazar.jpg |100px]] '''News and Announcements e-Board'''<br>
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* '''How plants maintain variability of genes involved in pathogen recognition and to which extent this variability is caused by the interaction with pathogens?'''  
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* '''How the environment manipulates immune responses? How this affects the above points?'''
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'''28.11.13'''
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Press release by the University of Barcelona from PNAS paper by [http://www.pnas.org/cgi/pmidlookup?view=long&pmid=24023067 Barboza et al.]<br>
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''' ‘Arabidopsis’ semidwarfs: the green revolution in nature''' <br>
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To address these and other questions, we (and others) developed a new model for plant immunity studies based on the use of ''Arabidopsis'' immune-related incompatible hybrids. These are hybrids obtained by crosses of natural ''Arabidopsis'' accessions that exhibit constitutive activation of defense, stunted growth and sterility in the absence of pathogen challenge. Often, such phenotypes are temperature-dependent and suppressed at high temperature.
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[http://www.ub.edu/web/ub/en/menu_eines/noticies/2013/11/063.html | Read in English ]
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[http://www.ub.edu/web/ub/ca/menu_eines/noticies/2013/11/063.html | Read in Catalan ]
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[http://www.ub.edu/web/ub/es/menu_eines/noticies/2013/11/063.html | Read in Spanish ]
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These genetic interactions might unravel molecular partners required for proper modulation of defense. Some of these cases are background-dependent and therefore, likely difficult to be observed in classical reference accessions.
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Since some years, we're using the Ler / Kas-2 immune-related hybrid incompatibility as molecular model to answer some of the questions above. The Landsberg (from Gorzów Wielkopolski, Poland)/Kashmir-2 (from Kashmir mountains) incompatibility involves populations in Central Europe and Central Asia which enable to expand our analyses to population scales. We apply population genetics on top of our molecular and biochemical analyses.  
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Derived from our research, we attempt to provide new strategies for crop protection at medium to long-term.  
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09.10.13 Deadline for submissions to [http://www.frontiersin.org/plant_metabolism_and_chemodiversity/researchtopics/plant_polyamines_in_stress_and/1527 Frontiers topic] approaching (31 Dec 2013).
 
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[http://www.ub.edu/farmacia/ The Faculty] | [http://www.ub.edu The University] | [http://bkc.upc.ub.edu/ The Campus] |
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<font face="helvetica" style="color:#000000" font size="3">
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[[Image:Announcement_alcazar.jpg |100px]] '''News and Announcements e-Board'''<br>
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  NEWS
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Master in Molecular Biotechnology (Trabajo Final de Máster) offers.
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[http://www.ub.edu/portal/web/farmacia/masters-universitaris/-/ensenyament/detallEnsenyament/483691/0 info]
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Contact us directly at ralcazar(at)ub.edu
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''' ACADEMIC PRESS RELEASES'''<br>
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[http://www.ub.edu/web/ub/en/menu_eines/noticies/2015/01/020.html? Alcázar Lab work highlighted by the University of Barcelona 20.01.15]<br>
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[http://www.ub.edu/noticies/cgi/event.pl?id=62490&noticiaub=FARMACIA Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015]<br>
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[http://sefv.net/files/sd_publicaciones/58.pdf Alcázar Lab work highlighted by the Bulletin of the Spanish Society of Plant Physiology, SEFV. January, 2015]<br>
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[http://www.mpipz.mpg.de/4042700/PM_Parker_2015 PLoS Genet 2014 highlight by Max Planck Institute, Cologne. 11.12.14.]<br>
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[http://www.ub.edu/web/ub/en/menu_eines/noticies/2013/11/063.html? Arabidopsis semidwarfs: the green revolution in nature] 02.12.2013. University of Barcelona.<br>
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[http://www.mpipz.mpg.de/5389/news_publication_619091 Hybrid plants with over-reactive immune system] 17.11.2010. Max Planck Society.
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<p>This wiki site is built under [http://www.openwetware.org Openwetware], an open access movement promoting the sharing of information among researchers.</p>
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Rubén Alcázar is Ramón y Cajal Researcher at the Department of Biology, Healthcare and Environment of the [http://www.ub.edu University of Barcelona].<br>
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<br>'''Research in Alcázar Lab is supported by:'''
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* 7th Framework Programme. Marie Curie Career Integration Grant (DISEASENVIRON, PCIG10-GA-2011-303568) of the European Union.
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* Ramón y Cajal Program (RYC-2011-07847) of the Ministerio de Ciencia e Innovación (Spain).
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* BFU2013-41337-P grant of the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia (Ministerio de Economía y Competitividad, Spain).
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Current revision

This webpage will be discontinued soon. A new webpage is hosted at the UB servers:
Please visit: http://www.ub.edu/portal/web/dp-bsma/stress



Dept. Biology, Healthcare & Environment
Section of Plant Physiology
Facultat de Farmàcia, Av. Joan XXIII 27-31
08028 Barcelona, Spain

Map


Dear visitor,

Welcome to the Molecular Genetics of Plant Stress Tolerance Lab (Ruben Alcazar & A.F. Tiburcio Labs) at the Department of Biology, Healthcare & Environment of the University of Barcelona.

We're a recently created joint research group that investigates the adaptation of plants to local environments. We focus on the evolutionary adaptation of plant populations to abiotic and biotic stresses, which are major challenges for plant survival under the current climate change predictions. Derived from our research, we investigate ways for improving stress protection.

For a more detailed view of our research, please have a look at our Research Projects and Scientific Publications sections. You can follow an updated list of our activities and publications in the NEWS section below. For any other enquires, do not hesitate to contact us directly.












1. POLYAMINE PERCEPTION AND SIGNALING


Our research laboratory has long-standing experience in the field of plant polyamines, for which we performed a number of omics approaches and established genetic evidence for their role in abiotic stress protection.


Our previous research pointed to interactions of polyamines with hormones and other stress-related metabolites. Our current goal is to investigate how polyamines are perceived by the plant, which early signaling components are involved, and how this is shaped by the environment.


We’re making use of background knowledge from different disciplines to gain insight into polyamine perception and signaling, for which little is known in plants. We’re making use of genetics of natural variation, reverse genetics, molecular biology and plant-microbe interactions to unravel how polyamines are sensed and how this relates to the local microbiota.


Our final goal is to provide novel approaches for crop protection against abiotic and biotic stresses.


Key words: stress tolerance, drought, salinity, freezing tolerance, priming, ROS, crop protection, microbiome, rhizosphere, polyamines, natural variation, transcriptional regulation, metabolon, modulon.


2. MOLECULAR EVOLUTION OF DISEASE RESISTANCE IN PLANTS


In our lab, we make use of the extensive natural variation of Arabidopsis thaliana populations to answer key fundamental questions:

  • How plants adapt to local environments including the microbiota?
  • How plants maintain variability of genes involved in pathogen recognition and to which extent this variability is caused by the interaction with pathogens?
  • How the environment manipulates immune responses? How this affects the above points?


To address these and other questions, we (and others) developed a new model for plant immunity studies based on the use of Arabidopsis immune-related incompatible hybrids. These are hybrids obtained by crosses of natural Arabidopsis accessions that exhibit constitutive activation of defense, stunted growth and sterility in the absence of pathogen challenge. Often, such phenotypes are temperature-dependent and suppressed at high temperature.


These genetic interactions might unravel molecular partners required for proper modulation of defense. Some of these cases are background-dependent and therefore, likely difficult to be observed in classical reference accessions.


Since some years, we're using the Ler / Kas-2 immune-related hybrid incompatibility as molecular model to answer some of the questions above. The Landsberg (from Gorzów Wielkopolski, Poland)/Kashmir-2 (from Kashmir mountains) incompatibility involves populations in Central Europe and Central Asia which enable to expand our analyses to population scales. We apply population genetics on top of our molecular and biochemical analyses.


Derived from our research, we attempt to provide new strategies for crop protection at medium to long-term.






News and Announcements e-Board

 NEWS
Master in Molecular Biotechnology (Trabajo Final de Máster) offers.
info
Contact us directly at ralcazar(at)ub.edu


ACADEMIC PRESS RELEASES

Alcázar Lab work highlighted by the University of Barcelona 20.01.15
Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015
Alcázar Lab work highlighted by the Bulletin of the Spanish Society of Plant Physiology, SEFV. January, 2015
PLoS Genet 2014 highlight by Max Planck Institute, Cologne. 11.12.14.
Arabidopsis semidwarfs: the green revolution in nature 02.12.2013. University of Barcelona.
Hybrid plants with over-reactive immune system 17.11.2010. Max Planck Society.



Rubén Alcázar is Ramón y Cajal Researcher at the Department of Biology, Healthcare and Environment of the University of Barcelona.



Research in Alcázar Lab is supported by:


  • 7th Framework Programme. Marie Curie Career Integration Grant (DISEASENVIRON, PCIG10-GA-2011-303568) of the European Union.
  • Ramón y Cajal Program (RYC-2011-07847) of the Ministerio de Ciencia e Innovación (Spain).
  • BFU2013-41337-P grant of the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia (Ministerio de Economía y Competitividad, Spain).

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