LabName:Alcazar: Difference between revisions

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'''''Dear visitor,'''''<br>
<br> Welcome to the webpage of the '''Molecular Genetics of Plant-Environment Interactions (Alcazar Lab)''' at the Department of Biology, Healthcare & Environment of the University of Barcelona. <br><br>
We're a recently created research group that investigates the '''adaptation of plants to local environments'''. We focus on the evolutionary adaptation of plant populations to '''abiotic and biotic stresses''', which are major challenges for plant survival under the current climate change predictions. Derived from our research, we investigate ways for improving stress protection.<br>
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For a more detailed view of our research, please have a look at our [http://alcazar.openwetware.org/Research.html Research Projects] and [http://alcazar.openwetware.org/Publications.html Scientific Publications] sections. You can follow an updated list of our activities and publications in the NEWS section below. For any other enquires, do not hesitate to contact us directly.<br><br>
[http://www.fv2017.org XXII Meeting of the Spanish Society of Plant Physiology, BCN 2017 26-29 June] <br>
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Info currently available in the following languages: <br>
[[http://alcazar.openwetware.org EN]] [[http://alcazar_cat.openwetware.org CAT]] [[http://alcazar_es.openwetware.org ES]]


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'''''What are we interested in?'''''


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'''MOLECULAR EVOLUTION OF DISEASE RESISTANCE IN PLANTS''' <br>
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We're interested in genetics of natural variation, population genetics, molecular biology and biochemistry. We want to know how climate change is shaping plant's resistance and tolerance traits under a combined multidisciplinary approach. Our lab undertakes a research approach that looks for the genetic and molecular basis of naturally occurring quantitative variation in biotic and abiotic stress responses, and how these interact with the environment (genotype-by-environment interactions). This multidisciplinary approach will allow a better understanding of the natural evolution of stress pathways in plants and efficient know-how transfer to practical applications.<br>
In our lab, we make use of the extensive natural variation of [https://en.wikipedia.org/wiki/Arabidopsis_thaliana ''Arabidopsis thaliana''] populations to answer key fundamental questions:


* '''How plants adapt to local environments including the microbiota?'''
* '''How plants maintain variability of genes involved in pathogen recognition and to which extent this variability is caused by the interaction with pathogens?'''
* '''How the environment manipulates immune responses? How this affects the above points?'''


For a more detailed view of our research plans, please have a look at our [http://openwetware.org/wiki/Alcazar:Research Research] and [http://openwetware.org/wiki/Alcazar:Publications Publications] sections.
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'''LATEST NEWS'''
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* Finally we're starting our activities in December. A great challenge in the current global economic scenario that should be somehow compensated with lots of motivation to make our research run.  [http://youtu.be/G3_hEGDaLXQ Let's go for it!]
* R.A. granted by Marie Curie Actions for the project DISEASENVIRON.
* Review on new open access journal 'Metabolites' published. [http://www.mdpi.com/2218-1989/2/3/516 read]
* Are you interested in joining us as PhD or Master student? Contact us by e-mail. [mailto:ralcazar@ub.edu Contact]
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'''PREVIOUS ANNOUNCEMENTS'''
To address these and other questions, we (and others) developed a new model for plant immunity studies based on the use of ''Arabidopsis'' immune-related incompatible hybrids. These are hybrids obtained by crosses of natural ''Arabidopsis'' accessions that exhibit constitutive activation of defense, stunted growth and sterility in the absence of pathogen challenge. Often, such phenotypes are temperature-dependent and suppressed at high temperature.


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* '''25.10.2012''' R.A. granted by Marie Curie Actions for the project DISEASENVIRON.
* '''25.10.2012'''  Review on new open access journal 'Metabolites' published. [http://www.mdpi.com/2218-1989/2/3/516 read]
*'''''08.10.2012''''' Interessat en realitzar la tesi doctoral o màster al nostre grup? Contacta per e-mail amb nosaltres.
*'''''04.10.2012''''' New lab webpage version released in OpenWetWare.
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'''''Línies de recerca'''''


El nostre és un laboratori interessat en l'estudi de les bases genètiques de l'estrés abiòtic i biòtic en plantes, emprant organismes model i espècies d'interés agronòmic, investiguem la variabilitat genètica natural existent en poblacions silvestres. La nostra és una recerca transversal que incorpora genètica de la variabilitat natural, genètica de poblacions, biologia molecular i bioquímica.
These genetic interactions might unravel molecular partners required for proper modulation of defense. Some of these cases are background-dependent and therefore, likely difficult to be observed in classical reference accessions.
Els detalls de la nostra recerca i projectes en curs es poden consultar en l'apartat "Research" i "Publications".
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Since some years, we're using the Ler / Kas-2 immune-related hybrid incompatibility as molecular model to answer some of the questions above. The Landsberg (from Gorzów Wielkopolski, Poland)/Kashmir-2 (from Kashmir mountains) incompatibility involves populations in Central Europe and Central Asia which enable to expand our analyses to population scales. We apply population genetics on top of our molecular and biochemical analyses.
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'''''Líneas de investigación'''''


Nuestro laboratorio tiene como principal línea de investigación el estudio de las bases genéticas del estrés abiótico y biótico. Para ello estudiamos la variabilidad genética natural existente en poblaciones naturales de especies modelo y de interés agronómico. Nuestra investigación es transversal e incluye genética de la variabilidad natural, genética de poblaciones, biología molecular y bioquímica.
Los detalles de nuestra investigación y proyectos en curso se pueden consultar en las secciones "Research" y "Publications".
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Derived from our research, we attempt to provide new strategies for crop protection at medium to long-term.






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[[Image:Announcement_alcazar.jpg |100px]] '''News and Announcements e-Board'''<br>
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LATEST NEWS
05/09/2016. Nazanin A. joins our lab as PhD student in the Biotechnology Program of UB.


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Publications 2016
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'''Address:'''
15/03/2016 In Frontiers Plant Sci: [http://journal.frontiersin.org/article/10.3389/fpls.2016.00401/abstract GWAS analysis for Arabidopsis guazatine tolerance]
22/01/2016 In Plant Cell & Environment:  [http://www.ncbi.nlm.nih.gov/pubmed/26791972 tSpm triggers salinity tolerance in Arabidopsis]
01/02/2016 In Frontiers Plant Sci: [http://journal.frontiersin.org/article/10.3389/fpls.2016.00173/abstract Metabolic profiling of atpao4 mutants under dark induced senescence]
In press: Drought Stress Tolerance in Relation to Polyamine Metabolism in Plants, book chapter in Springer.


Facultat de Farmàcia - Universitat de Barcelona (UB) <br>
''' ACADEMIC PRESS RELEASES'''<br>
Departament de Productes Naturals, Biologia Vegetal i Edafologia<br>
[http://www.ub.edu/web/ub/en/menu_eines/noticies/2015/01/020.html? Alcázar Lab work highlighted by the University of Barcelona 20.01.15]<br>
Unitat de Fisiologia Vegetal - Edifici A, 2a Planta <br>
[http://www.ub.edu/noticies/cgi/event.pl?id=62490&noticiaub=FARMACIA Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015]<br>
Diagonal 643, 08028 Barcelona<br>
[http://sefv.net/files/sd_publicaciones/58.pdf Alcázar Lab work highlighted by the Bulletin of the Spanish Society of Plant Physiology, SEFV. January, 2015]<br>
Spain<br>
[http://www.mpipz.mpg.de/4042700/PM_Parker_2015 PLoS Genet 2014 highlight by Max Planck Institute, Cologne. 11.12.14.]<br>
[http://www.ub.edu/web/ub/en/menu_eines/noticies/2013/11/063.html? Arabidopsis semidwarfs: the green revolution in nature] 02.12.2013. University of Barcelona.<br>
[http://www.mpipz.mpg.de/5389/news_publication_619091 Hybrid plants with over-reactive immune system] 17.11.2010. Max Planck Society.
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Rubén Alcázar is Ramón y Cajal Researcher at the Department of Natural Products, Plant Biology and Soil Science of the [http://www.ub.edu University of Barcelona].<br>
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<br>'''Research in Alcázar Lab is supported by:'''
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* 7th Framework Programme. Marie Curie Career Integration Grant (DISEASENVIRON, PCIG10-GA-2011-303568) of the European Union.
* Ramón y Cajal Program (RYC-2011-07847) of the Ministerio de Ciencia e Innovación (Spain).
* BFU2013-41337-P grant of the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia (Ministerio de Economía y Competitividad, Spain).


<p>This wiki site is built under [http://www.openwetware.org Openwetware],  an open access movement promoting the sharing of information among researchers.</p>
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Lab website is still under construction.
--[[User:Ruben Alcazar|Ruben Alcazar]] 4 October 2012

Revision as of 05:23, 5 September 2016




Dept. Biology, Healthcare & Environment
Section of Plant Physiology
Facultat de Farmàcia, Av. Joan XXIII 27-31
08028 Barcelona, Spain

<html><a href="http://www.revolvermaps.com/?target=enlarge&i=0ewrbw4fec7"><img src="//ra.revolvermaps.com/h/m/a/0/fff600/128/40/0ewrbw4fec7.png" width="156" height="100" alt="Map" style="border:0;"></a>


Dear visitor,

Welcome to the webpage of the Molecular Genetics of Plant-Environment Interactions (Alcazar Lab) at the Department of Biology, Healthcare & Environment of the University of Barcelona.

We're a recently created research group that investigates the adaptation of plants to local environments. We focus on the evolutionary adaptation of plant populations to abiotic and biotic stresses, which are major challenges for plant survival under the current climate change predictions. Derived from our research, we investigate ways for improving stress protection.

For a more detailed view of our research, please have a look at our Research Projects and Scientific Publications sections. You can follow an updated list of our activities and publications in the NEWS section below. For any other enquires, do not hesitate to contact us directly.

XXII Meeting of the Spanish Society of Plant Physiology, BCN 2017 26-29 June
Info currently available in the following languages:
[EN] [CAT] [ES]









MOLECULAR EVOLUTION OF DISEASE RESISTANCE IN PLANTS


In our lab, we make use of the extensive natural variation of Arabidopsis thaliana populations to answer key fundamental questions:

  • How plants adapt to local environments including the microbiota?
  • How plants maintain variability of genes involved in pathogen recognition and to which extent this variability is caused by the interaction with pathogens?
  • How the environment manipulates immune responses? How this affects the above points?


To address these and other questions, we (and others) developed a new model for plant immunity studies based on the use of Arabidopsis immune-related incompatible hybrids. These are hybrids obtained by crosses of natural Arabidopsis accessions that exhibit constitutive activation of defense, stunted growth and sterility in the absence of pathogen challenge. Often, such phenotypes are temperature-dependent and suppressed at high temperature.


These genetic interactions might unravel molecular partners required for proper modulation of defense. Some of these cases are background-dependent and therefore, likely difficult to be observed in classical reference accessions.


Since some years, we're using the Ler / Kas-2 immune-related hybrid incompatibility as molecular model to answer some of the questions above. The Landsberg (from Gorzów Wielkopolski, Poland)/Kashmir-2 (from Kashmir mountains) incompatibility involves populations in Central Europe and Central Asia which enable to expand our analyses to population scales. We apply population genetics on top of our molecular and biochemical analyses.


Derived from our research, we attempt to provide new strategies for crop protection at medium to long-term.



News and Announcements e-Board

LATEST NEWS
05/09/2016. Nazanin A. joins our lab as PhD student in the Biotechnology Program of UB.
Publications 2016

15/03/2016 In Frontiers Plant Sci: GWAS analysis for Arabidopsis guazatine tolerance

22/01/2016 In Plant Cell & Environment:  tSpm triggers salinity tolerance in Arabidopsis

01/02/2016 In Frontiers Plant Sci: Metabolic profiling of atpao4 mutants under dark induced senescence

In press: Drought Stress Tolerance in Relation to Polyamine Metabolism in Plants, book chapter in Springer.

ACADEMIC PRESS RELEASES

Alcázar Lab work highlighted by the University of Barcelona 20.01.15
Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015
Alcázar Lab work highlighted by the Bulletin of the Spanish Society of Plant Physiology, SEFV. January, 2015
PLoS Genet 2014 highlight by Max Planck Institute, Cologne. 11.12.14.
Arabidopsis semidwarfs: the green revolution in nature 02.12.2013. University of Barcelona.
Hybrid plants with over-reactive immune system 17.11.2010. Max Planck Society.



Rubén Alcázar is Ramón y Cajal Researcher at the Department of Natural Products, Plant Biology and Soil Science of the University of Barcelona.



Research in Alcázar Lab is supported by:


  • 7th Framework Programme. Marie Curie Career Integration Grant (DISEASENVIRON, PCIG10-GA-2011-303568) of the European Union.
  • Ramón y Cajal Program (RYC-2011-07847) of the Ministerio de Ciencia e Innovación (Spain).
  • BFU2013-41337-P grant of the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia (Ministerio de Economía y Competitividad, Spain).