LabName:Alcazar: Difference between revisions
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- | **** New lab webpage hosted at University of Barcelona servers*** | ||
Please visit: http://www.ub.edu/portal/web/dp-bsma/stress | |||
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'''''Dear visitor,'''''<br> | |||
<br> Welcome to the Molecular Genetics of Plant Stress Tolerance Lab (Ruben Alcazar & A.F. Tiburcio Labs) ''' at the Department of Biology, Healthcare & Environment of the University of Barcelona. <br><br> | |||
We're a recently created joint research group that investigates the '''adaptation of plants to local environments'''. We focus on the evolutionary adaptation of plant populations to '''abiotic and biotic stresses''', which are major challenges for plant survival under the current climate change predictions. Derived from our research, we investigate ways for improving stress protection.<br> | |||
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For a more detailed view of our research, please have a look at our [http://alcazar.openwetware.org/Research.html Research Projects] and [http://alcazar.openwetware.org/Publications.html Scientific Publications] sections. You can follow an updated list of our activities and publications in the NEWS section below. For any other enquires, do not hesitate to contact us directly.<br><br> | |||
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'''1. POLYAMINE PERCEPTION AND SIGNALING''' | |||
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[[Image:Polyamines.jpg|300px]] | |||
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Our research laboratory has long-standing experience in the field of plant polyamines, for which we performed a number of omics approaches and established genetic evidence for their role in abiotic stress protection. | |||
Our previous research pointed to interactions of polyamines with hormones and other stress-related metabolites. Our current goal is to investigate how polyamines are perceived by the plant, which early signaling components are involved, and how this is shaped by the environment. | |||
We’re making use of background knowledge from different disciplines to gain insight into polyamine perception and signaling, for which little is known in plants. We’re making use of genetics of natural variation, reverse genetics, molecular biology and plant-microbe interactions to unravel how polyamines are sensed and how this relates to the local microbiota. | |||
Our final goal is to provide novel approaches for crop protection against abiotic and biotic stresses. | |||
Key words: stress tolerance, drought, salinity, freezing tolerance, priming, ROS, crop protection, microbiome, rhizosphere, polyamines, natural variation, transcriptional regulation, metabolon, modulon. | |||
'''2. MOLECULAR EVOLUTION OF DISEASE RESISTANCE IN PLANTS''' <br> | |||
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In our lab, we make use of the extensive natural variation of [https://en.wikipedia.org/wiki/Arabidopsis_thaliana ''Arabidopsis thaliana''] populations to answer key fundamental questions: | |||
* '''How plants adapt to local environments including the microbiota?''' | |||
* '''How plants maintain variability of genes involved in pathogen recognition and to which extent this variability is caused by the interaction with pathogens?''' | |||
* '''How the environment manipulates immune responses? How this affects the above points?''' | |||
To address these and other questions, we (and others) developed a new model for plant immunity studies based on the use of ''Arabidopsis'' immune-related incompatible hybrids. These are hybrids obtained by crosses of natural ''Arabidopsis'' accessions that exhibit constitutive activation of defense, stunted growth and sterility in the absence of pathogen challenge. Often, such phenotypes are temperature-dependent and suppressed at high temperature. | |||
These genetic interactions might unravel molecular partners required for proper modulation of defense. Some of these cases are background-dependent and therefore, likely difficult to be observed in classical reference accessions. | |||
Since some years, we're using the Ler / Kas-2 immune-related hybrid incompatibility as molecular model to answer some of the questions above. The Landsberg (from Gorzów Wielkopolski, Poland)/Kashmir-2 (from Kashmir mountains) incompatibility involves populations in Central Europe and Central Asia which enable to expand our analyses to population scales. We apply population genetics on top of our molecular and biochemical analyses. | |||
Derived from our research, we attempt to provide new strategies for crop protection at medium to long-term. | |||
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[[Image:Announcement_alcazar.jpg |100px]] '''News and Announcements e-Board'''<br> | |||
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NEWS | |||
Master in Molecular Biotechnology (Trabajo Final de Máster) offers. | |||
[http://www.ub.edu/portal/web/farmacia/masters-universitaris/-/ensenyament/detallEnsenyament/483691/0 info] | |||
Contact us directly at ralcazar(at)ub.edu | |||
''' ACADEMIC PRESS RELEASES'''<br> | |||
[http://www.ub.edu/web/ub/en/menu_eines/noticies/2015/01/020.html? Alcázar Lab work highlighted by the University of Barcelona 20.01.15]<br> | |||
[http://www.ub.edu/noticies/cgi/event.pl?id=62490¬iciaub=FARMACIA Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015]<br> | |||
[http://sefv.net/files/sd_publicaciones/58.pdf Alcázar Lab work highlighted by the Bulletin of the Spanish Society of Plant Physiology, SEFV. January, 2015]<br> | |||
[http://www.mpipz.mpg.de/4042700/PM_Parker_2015 PLoS Genet 2014 highlight by Max Planck Institute, Cologne. 11.12.14.]<br> | |||
[http://www.ub.edu/web/ub/en/menu_eines/noticies/2013/11/063.html? Arabidopsis semidwarfs: the green revolution in nature] 02.12.2013. University of Barcelona.<br> | |||
[http://www.mpipz.mpg.de/5389/news_publication_619091 Hybrid plants with over-reactive immune system] 17.11.2010. Max Planck Society. | |||
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Rubén Alcázar is Ramón y Cajal Researcher at the Department of Biology, Healthcare and Environment of the [http://www.ub.edu University of Barcelona].<br> | |||
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<br>'''Research in Alcázar Lab is supported by:''' | |||
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* 7th Framework Programme. Marie Curie Career Integration Grant (DISEASENVIRON, PCIG10-GA-2011-303568) of the European Union. | |||
* Ramón y Cajal Program (RYC-2011-07847) of the Ministerio de Ciencia e Innovación (Spain). | |||
* BFU2013-41337-P grant of the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia (Ministerio de Economía y Competitividad, Spain). | |||
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Revision as of 01:53, 11 August 2017
**** New lab webpage hosted at University of Barcelona servers***
Please visit: http://www.ub.edu/portal/web/dp-bsma/stress
Dept. Biology, Healthcare & Environment
Section of Plant Physiology
Facultat de Farmàcia, Av. Joan XXIII 27-31
08028 Barcelona, Spain
<html><a href="http://www.revolvermaps.com/?target=enlarge&i=0ewrbw4fec7"><img src="//ra.revolvermaps.com/h/m/a/0/fff600/128/40/0ewrbw4fec7.png" width="156" height="100" alt="Map" style="border:0;"></a>
Dear visitor,
Welcome to the Molecular Genetics of Plant Stress Tolerance Lab (Ruben Alcazar & A.F. Tiburcio Labs) at the Department of Biology, Healthcare & Environment of the University of Barcelona.
We're a recently created joint research group that investigates the adaptation of plants to local environments. We focus on the evolutionary adaptation of plant populations to abiotic and biotic stresses, which are major challenges for plant survival under the current climate change predictions. Derived from our research, we investigate ways for improving stress protection.
For a more detailed view of our research, please have a look at our Research Projects and Scientific Publications sections. You can follow an updated list of our activities and publications in the NEWS section below. For any other enquires, do not hesitate to contact us directly.
1. POLYAMINE PERCEPTION AND SIGNALING
Our research laboratory has long-standing experience in the field of plant polyamines, for which we performed a number of omics approaches and established genetic evidence for their role in abiotic stress protection.
Our previous research pointed to interactions of polyamines with hormones and other stress-related metabolites. Our current goal is to investigate how polyamines are perceived by the plant, which early signaling components are involved, and how this is shaped by the environment.
We’re making use of background knowledge from different disciplines to gain insight into polyamine perception and signaling, for which little is known in plants. We’re making use of genetics of natural variation, reverse genetics, molecular biology and plant-microbe interactions to unravel how polyamines are sensed and how this relates to the local microbiota.
Our final goal is to provide novel approaches for crop protection against abiotic and biotic stresses.
Key words: stress tolerance, drought, salinity, freezing tolerance, priming, ROS, crop protection, microbiome, rhizosphere, polyamines, natural variation, transcriptional regulation, metabolon, modulon.
2. MOLECULAR EVOLUTION OF DISEASE RESISTANCE IN PLANTS
In our lab, we make use of the extensive natural variation of Arabidopsis thaliana populations to answer key fundamental questions:
- How plants adapt to local environments including the microbiota?
- How plants maintain variability of genes involved in pathogen recognition and to which extent this variability is caused by the interaction with pathogens?
- How the environment manipulates immune responses? How this affects the above points?
To address these and other questions, we (and others) developed a new model for plant immunity studies based on the use of Arabidopsis immune-related incompatible hybrids. These are hybrids obtained by crosses of natural Arabidopsis accessions that exhibit constitutive activation of defense, stunted growth and sterility in the absence of pathogen challenge. Often, such phenotypes are temperature-dependent and suppressed at high temperature.
These genetic interactions might unravel molecular partners required for proper modulation of defense. Some of these cases are background-dependent and therefore, likely difficult to be observed in classical reference accessions.
Since some years, we're using the Ler / Kas-2 immune-related hybrid incompatibility as molecular model to answer some of the questions above. The Landsberg (from Gorzów Wielkopolski, Poland)/Kashmir-2 (from Kashmir mountains) incompatibility involves populations in Central Europe and Central Asia which enable to expand our analyses to population scales. We apply population genetics on top of our molecular and biochemical analyses.
Derived from our research, we attempt to provide new strategies for crop protection at medium to long-term.
News and Announcements e-Board
NEWS Master in Molecular Biotechnology (Trabajo Final de Máster) offers. info Contact us directly at ralcazar(at)ub.edu
ACADEMIC PRESS RELEASES
Alcázar Lab work highlighted by the University of Barcelona 20.01.15
Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015
Alcázar Lab work highlighted by the Bulletin of the Spanish Society of Plant Physiology, SEFV. January, 2015
PLoS Genet 2014 highlight by Max Planck Institute, Cologne. 11.12.14.
Arabidopsis semidwarfs: the green revolution in nature 02.12.2013. University of Barcelona.
Hybrid plants with over-reactive immune system 17.11.2010. Max Planck Society.
Rubén Alcázar is Ramón y Cajal Researcher at the Department of Biology, Healthcare and Environment of the University of Barcelona.
Research in Alcázar Lab is supported by:
- 7th Framework Programme. Marie Curie Career Integration Grant (DISEASENVIRON, PCIG10-GA-2011-303568) of the European Union.
- Ramón y Cajal Program (RYC-2011-07847) of the Ministerio de Ciencia e Innovación (Spain).
- BFU2013-41337-P grant of the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia (Ministerio de Economía y Competitividad, Spain).
