Lauffenburger:Laura Sontag

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Revision as of 07:20, 6 April 2009

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Laura Kleiman (Computational and Systems Biology doctoral student)

Advisors: Peter Sorger (BE - MIT, Systems Biology - HMS) and Douglas Lauffenburger (BE/ChemE/Biology - MIT)

Computational and experimental analysis of ErbB receptor signaling and oncogenic K-Ras mutations.

Email: sontag {AT} mit {DOT} edu

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 [[Image:Laura_Sontag.JPG|150px|right]]
-'''Laura Sontag''' (Computational and Systems Biology doctoral student)
+'''Laura Kleiman''' (Computational and Systems Biology doctoral student)
-Advisors: Professors Peter Sorger (Biology/BE, MIT) and Douglas Lauffenburger (BE/ChemE/Biology, MIT), in collaboration with Professor Tyler Jacks (Biology/Center for Cancer Research, MIT)
+Advisors: Peter Sorger (BE - MIT, Systems Biology - HMS) and Douglas Lauffenburger (BE/ChemE/Biology - MIT)
-Computational and experimental analysis of mitogenic signaling pathways
-activated by oncogenic Ras.  The Ras signaling cascade
-constitutes a major pathway shown to be deregulated due to activating
-mutations in 30% of all human tumors.  The vast majority of mutations occur in the K-ras gene.  We use genetically engineered mice that harbor a conditional,
-activatable K-ras allele as a model of human cancer.
+Computational and experimental analysis of ErbB receptor signaling and oncogenic K-Ras mutations.
 Email:  sontag {AT} mit {DOT} edu
-[http://www.mit.edu/~sontag/ Laura Sontag's Homepage]
+[http://www.mit.edu/~sontag/ Laura Kleiman's Homepage]
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