Lauffenburger:Laura Sontag

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Laura Sontag-Kleiman (Computational and Systems Biology doctoral student)

Advisors: Peter Sorger (BE - MIT, Systems Biology - HMS) and Doug Lauffenburger (BE/ChemE/Biology - MIT)

Computational and experimental analysis of ErbB receptor signaling and oncogenic K-Ras mutations.

Email: sontag {AT} mit {DOT} edu

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-[[Image:Laura_Sontag.JPG|150px|right]]
+[[Image:Laura_Sontag-Kleiman.jpg|150px|right]]
-'''Laura Sontag''' (CSB doctoral), in collaboration with Prof. Peter Sorger
+'''Laura Sontag-Kleiman''' (Computational and Systems Biology doctoral student)
-(Biology/BE, MIT) and Prof. Tyler Jacks (Biology/Center for Cancer Research,
-MIT)
-Computational and experimental analysis of mitogenic signaling pathways
+Advisors: Peter Sorger (BE - MIT, Systems Biology - HMS) and Doug Lauffenburger (BE/ChemE/Biology - MIT)
-activated by a mutation in the K-ras oncogene.  The Ras signaling cascade
-constitutes a major pathway shown to be misregulated due to activating
-mutations in 30% of all human tumors.  The vast majority of mutations occur in
-K-ras.  We use genetically engineered mice that harbor a conditional,
-activatable allele of the K-ras oncogene as a model of human cancer.
+Computational and experimental analysis of ErbB receptor signaling and oncogenic K-Ras mutations.
+Email:  sontag {AT} mit {DOT} edu
+[http://www.mit.edu/~sontag/ Laura Kleiman's Homepage]
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