Lauffenburger:Laura Sontag

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[[Image:Laura_Sontag.JPG|150px|right]]
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[[Image:Laura_Sontag-Kleiman.jpg|150px|right]]
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'''Laura Sontag''' (Computational and Systems Biology doctoral student)
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'''Laura Sontag-Kleiman''' (Computational and Systems Biology doctoral student)
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Advisors: Professors Peter Sorger (Biology/BE, MIT) and Douglas Lauffenburger (BE/ChemE/Biology, MIT), in collaboration with Professor Tyler Jacks (Biology/Center for Cancer Research, MIT)
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Advisors: Peter Sorger (BE - MIT, Systems Biology - HMS) and Doug Lauffenburger (BE/ChemE/Biology - MIT)
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Computational and experimental analysis of mitogenic signaling pathways
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activated by oncogenic Ras.  The Ras signaling cascade
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constitutes a major pathway shown to be deregulated due to activating
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mutations in 30% of all human tumors.  The vast majority of mutations occur in the K-ras gene.  We use genetically engineered mice that harbor a conditional,
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activatable K-ras allele as a model of human cancer.
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Computational and experimental analysis of ErbB receptor signaling and oncogenic K-Ras mutations.
Email:  sontag {AT} mit {DOT} edu
Email:  sontag {AT} mit {DOT} edu
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[http://www.mit.edu/~sontag/ Laura Sontag's Homepage]
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[http://www.mit.edu/~sontag/ Laura Kleiman's Homepage]
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Laura Sontag-Kleiman (Computational and Systems Biology doctoral student)

Advisors: Peter Sorger (BE - MIT, Systems Biology - HMS) and Doug Lauffenburger (BE/ChemE/Biology - MIT)

Computational and experimental analysis of ErbB receptor signaling and oncogenic K-Ras mutations.

Email: sontag {AT} mit {DOT} edu

Laura Kleiman's Homepage

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