Lauffenburger:Laura Sontag: Difference between revisions
From OpenWetWare
Jump to navigationJump to search
mNo edit summary |
No edit summary |
||
Line 6: | Line 6: | ||
[[Image:Laura_Sontag.JPG|150px|right]] | [[Image:Laura_Sontag.JPG|150px|right]] | ||
'''Laura Sontag''' (Computational and Systems Biology doctoral student) | '''Laura Sontag''' (Computational and Systems Biology doctoral student) | ||
MIT) | Advisors: Professors Peter Sorger (Biology/BE, MIT) and Doug Lauffenburger (Biology/BE, MIT), in collaboration with Prof. Tyler Jacks (Biology/Center for Cancer Research, MIT) | ||
Line 13: | Line 13: | ||
activated by mutations in the K-ras oncogene. The Ras signaling cascade | activated by mutations in the K-ras oncogene. The Ras signaling cascade | ||
constitutes a major pathway shown to be deregulated due to activating | constitutes a major pathway shown to be deregulated due to activating | ||
mutations in 30% of all human tumors. The vast majority of mutations occur in | mutations in 30% of all human tumors. The vast majority of mutations occur in K-ras. We use genetically engineered mice that harbor a conditional, | ||
K-ras | |||
activatable K-ras allele as a model of human cancer. | activatable K-ras allele as a model of human cancer. | ||
Revision as of 14:31, 5 February 2006
Laura Sontag (Computational and Systems Biology doctoral student) Advisors: Professors Peter Sorger (Biology/BE, MIT) and Doug Lauffenburger (Biology/BE, MIT), in collaboration with Prof. Tyler Jacks (Biology/Center for Cancer Research, MIT)
|