Lauffenburger:Laura Sontag: Difference between revisions
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[[Image:Laura_Sontag.JPG|150px|right]] | [[Image:Laura_Sontag.JPG|150px|right]] | ||
'''Laura Sontag''' ( | '''Laura Sontag''' (Computational and Systems Biology doctoral student), in collaboration with Prof. Peter Sorger (Biology/BE, MIT) and Prof. Tyler Jacks (Biology/Center for Cancer Research, | ||
(Biology/BE, MIT) and Prof. Tyler Jacks (Biology/Center for Cancer Research, | |||
MIT) | MIT) | ||
Computational and experimental analysis of mitogenic signaling pathways | Computational and experimental analysis of mitogenic signaling pathways | ||
activated by | activated by mutations in the K-ras oncogene. The Ras signaling cascade | ||
constitutes a major pathway shown to be | constitutes a major pathway shown to be deregulated due to activating | ||
mutations in 30% of all human tumors. The vast majority of mutations occur in | mutations in 30% of all human tumors. The vast majority of mutations occur in the | ||
K-ras. We use genetically engineered mice that harbor a conditional, | K-ras isoform. We use genetically engineered mice that harbor a conditional, | ||
activatable | activatable K-ras allele as a model of human cancer. | ||
Email: sontag {AT} mit {DOT} edu | |||
[http://www.mit.edu/~sontag/ Laura Sontag's Homepage] | |||
</div> | </div> | ||
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Revision as of 14:46, 6 January 2006
 Laura Sontag (Computational and Systems Biology doctoral student), in collaboration with Prof. Peter Sorger (Biology/BE, MIT) and Prof. Tyler Jacks (Biology/Center for Cancer Research, MIT)
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