Lauffenburger Lab - Revision history

Skosuri at 22:14, 5 December 2005

Skosuri — Mon, 05 Dec 2005 22:14:59 GMT

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	'''Molecular cell bioengineering''' is the application of engineering approaches to develop quantitative understanding of cell function in terms of fundamental molecular properties, and to apply this understanding for improved design of molecular- and cell-based technologies. Our research group focuses on elucidating important aspects of receptor-mediated regulation of mammalian blood and tissue cell behavioral functions such as proliferation, adhesion, migration, differentiation, and death. A central paradigm of our work is development and testing of computational models -- based on principles from engineering analysis and synthesis -- for receptor regulation of cell function by exploiting techniques of molecular biology to alter parameters characterizing receptor or ligand properties in well-characterized cell systems. Quantitative experimental assays are used to measure cell functions, receptor/ligand interaction parameters, and signaling network dynamics. Problems are primarily motivated by health care technologies of interest to pharmaceutical and biotechnological companies, and emphasize multi-disciplinary collaborative interactions, including colleagues in both academia and industry.		'''Molecular cell bioengineering''' is the application of engineering approaches to develop quantitative understanding of cell function in terms of fundamental molecular properties, and to apply this understanding for improved design of molecular- and cell-based technologies. Our research group focuses on elucidating important aspects of receptor-mediated regulation of mammalian blood and tissue cell behavioral functions such as proliferation, adhesion, migration, differentiation, and death. A central paradigm of our work is development and testing of computational models -- based on principles from engineering analysis and synthesis -- for receptor regulation of cell function by exploiting techniques of molecular biology to alter parameters characterizing receptor or ligand properties in well-characterized cell systems. Quantitative experimental assays are used to measure cell functions, receptor/ligand interaction parameters, and signaling network dynamics. Problems are primarily motivated by health care technologies of interest to pharmaceutical and biotechnological companies, and emphasize multi-disciplinary collaborative interactions, including colleagues in both academia and industry.
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Aran at 22:10, 5 December 2005

Aran — Mon, 05 Dec 2005 22:10:03 GMT

←Older revision		Revision as of 22:10, 5 December 2005
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	'''Molecular cell bioengineering''' is the application of engineering approaches to develop quantitative understanding of cell function in terms of fundamental molecular properties, and to apply this understanding for improved design of molecular- and cell-based technologies. Our research group focuses on elucidating important aspects of receptor-mediated regulation of mammalian blood and tissue cell behavioral functions such as proliferation, adhesion, migration, differentiation, and death. A central paradigm of our work is development and testing of computational models -- based on principles from engineering analysis and synthesis -- for receptor regulation of cell function by exploiting techniques of molecular biology to alter parameters characterizing receptor or ligand properties in well-characterized cell systems. Quantitative experimental assays are used to measure cell functions, receptor/ligand interaction parameters, and signaling network dynamics. Problems are primarily motivated by health care technologies of interest to pharmaceutical and biotechnological companies, and emphasize multi-disciplinary collaborative interactions, including colleagues in both academia and industry.		'''Molecular cell bioengineering''' is the application of engineering approaches to develop quantitative understanding of cell function in terms of fundamental molecular properties, and to apply this understanding for improved design of molecular- and cell-based technologies. Our research group focuses on elucidating important aspects of receptor-mediated regulation of mammalian blood and tissue cell behavioral functions such as proliferation, adhesion, migration, differentiation, and death. A central paradigm of our work is development and testing of computational models -- based on principles from engineering analysis and synthesis -- for receptor regulation of cell function by exploiting techniques of molecular biology to alter parameters characterizing receptor or ligand properties in well-characterized cell systems. Quantitative experimental assays are used to measure cell functions, receptor/ligand interaction parameters, and signaling network dynamics. Problems are primarily motivated by health care technologies of interest to pharmaceutical and biotechnological companies, and emphasize multi-disciplinary collaborative interactions, including colleagues in both academia and industry.
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Skosuri at 20:43, 18 September 2005

Skosuri — Sun, 18 Sep 2005 20:43:53 GMT

←Older revision		Revision as of 20:43, 18 September 2005
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-	~~<div style="padding: .4em .9em .9em">~~
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-	~~<h3>People</h3>~~
-	~~• [[Doug Lauffenburger]] <br>~~
-	~~• [[Lauffenburger:Lab Members\|Lab Members]] <br>~~
-	~~• [[Lauffenburger:Alumni\|Alumni]]<br>~~
-	~~• [[Lauffenburger:Collaborators\|Collaborators]]<br>~~
-	~~• [[Lauffenburger:Photo Album\|Photo Album]]<br>~~
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-	~~</div>~~
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-	~~<div style="clear: right; text-align: left; float: left; padding: .4em .9em .9em">~~
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-	~~<h3>Research</h3>~~
-	~~• [[Lauffenburger:Cell Signaling and Regulatory Networks\|Cell Signaling and Regulatory Networks]]<br>~~
-	~~• [[Lauffenburger:Cell Substratum Adhesion, Signaling, and Migration\|Cell Substratum Adhesion, Signaling, and Migration]]<br>~~
-	~~• [[Lauffenburger:Design of Biomolecular Therepeutics\|Design of Biomolecular Therepeutics]] <br>~~
-	~~----~~
-	~~• [[Lauffenburger:Lab Policies\|Lab Policies]]<br>~~
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-	~~<div style="padding: .4em .9em .9em">~~
-	~~<h3>Links</h3>~~
-	~~• [[Lauffenburger:Tools\|Tools]]<br>~~
-	~~• [http://web.mit.edu/dallab/index.html DL Lab Homepage]<br>~~
-	~~• [http://web.mit.edu/cheme/index.html MIT Chemical Engineering]<br>~~
-	~~• [http://web.mit.edu/cbe/www/ Center for Biomedical Engineering]<br>~~
-	~~• [http://web.mit.edu/cbe/www/ Center for Biomedical Engineering]<br>~~
-	~~• [http://web.mit.edu/ccr Center for Cancer Research]<br>~~
-	~~• [http://web.mit.edu/be Biological Engineering Division]<br>~~
-	~~• [http://web.mit.edu/bpec/ Biotechnology Process Engineering Center]<br>~~
-	~~• [http://mit.edu/biology/www/ Department of Biology]<br>~~
-	~~• [http://web.mit.edu/ MIT]~~
-	~~</div>~~
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Skosuri at 20:40, 18 September 2005

Skosuri — Sun, 18 Sep 2005 20:40:21 GMT

←Older revision		Revision as of 20:40, 18 September 2005
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Skosuri at 20:39, 18 September 2005

Skosuri — Sun, 18 Sep 2005 20:39:52 GMT

←Older revision		Revision as of 20:39, 18 September 2005
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Skosuri at 20:38, 18 September 2005

Skosuri — Sun, 18 Sep 2005 20:38:44 GMT

←Older revision		Revision as of 20:38, 18 September 2005
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-	~~<div style="padding: 3px; color: #ffffff; background-color: #9966FF; width: 750px"></div>~~	+	{{Lauffenburger Top}}
-	~~<div style="padding: 3px; color: #ffffff; background-color: #99CCFF; width: 750px"></div>~~	+
-	~~<div style="padding: 1px; color: #ffffff; background-color: #336633; width: 754px"></div>~~	+
-	~~<div style="padding: 20px; color: #ffffff; background-color: #ffffff; width: 750px">~~	+
-	~~<font face="trebuchet ms" style="color:#3333CC" size="6">~~	+
-	~~'''Doug~~ Lauffenburger~~'s Research Group'''~~	+
-	~~</font>~~	+
-	~~</div>~~	+
-	~~<div style="padding: 10px; color: #ffffff; background-color: #9966FF; width: 740px">~~	+
-	~~<center>~~	+
-	~~[[Lauffenburger Lab\| <font face="trebuchet ms" style="color:#ffffff"> '''Home''' </font>]]       ~~	+
-	~~[[Lauffenburger:People\| <font face="trebuchet ms" style="color:#ffffff"> '''People''' </font>]]       ~~	+
-	~~[[Lauffenburger:Research\| <font face="trebuchet ms" style="color:#ffffff"> '''Research''' </font>]]       ~~	+
-	~~[[Lauffenburger:Publications\| <font face="trebuchet ms" style="color:#ffffff"> '''Publications''' </font>]]       ~~	+
-	~~[[Lauffenburger:Links\| <font face="trebuchet ms" style="color:#ffffff"> '''Links''' </font>]]       ~~	+
-	~~[[Lauffenburger:Internal\| <font face="trebuchet ms" style="color:#ffffff"> '''Internal''' </font>]]       ~~	+
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Skosuri at 20:36, 18 September 2005

Skosuri — Sun, 18 Sep 2005 20:36:48 GMT

←Older revision		Revision as of 20:36, 18 September 2005
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	[[Lauffenburger:People\| <font face="trebuchet ms" style="color:#ffffff"> '''People''' </font>]]		[[Lauffenburger:People\| <font face="trebuchet ms" style="color:#ffffff"> '''People''' </font>]]
	[[Lauffenburger:Research\| <font face="trebuchet ms" style="color:#ffffff"> '''Research''' </font>]]		[[Lauffenburger:Research\| <font face="trebuchet ms" style="color:#ffffff"> '''Research''' </font>]]
-	[[~~Synthetic Biology~~:Publications\| <font face="trebuchet ms" style="color:#ffffff"> '''Publications''' </font>]]	+	[[Lauffenburger:Publications\| <font face="trebuchet ms" style="color:#ffffff"> '''Publications''' </font>]]
-	[[~~Synthetic Biology~~:Internal\| <font face="trebuchet ms" style="color:#ffffff"> '''Internal''' </font>]]	+	[[Lauffenburger:Links\| <font face="trebuchet ms" style="color:#ffffff"> '''Links''' </font>]]
		+	[[Lauffenburger:Internal\| <font face="trebuchet ms" style="color:#ffffff"> '''Internal''' </font>]]
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Skosuri at 20:35, 18 September 2005

Skosuri — Sun, 18 Sep 2005 20:35:23 GMT

←Older revision		Revision as of 20:35, 18 September 2005
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		+	'''Molecular cell bioengineering''' is the application of engineering approaches to develop quantitative understanding of cell function in terms of fundamental molecular properties, and to apply this understanding for improved design of molecular- and cell-based technologies. Our research group focuses on elucidating important aspects of receptor-mediated regulation of mammalian blood and tissue cell behavioral functions such as proliferation, adhesion, migration, differentiation, and death. A central paradigm of our work is development and testing of computational models -- based on principles from engineering analysis and synthesis -- for receptor regulation of cell function by exploiting techniques of molecular biology to alter parameters characterizing receptor or ligand properties in well-characterized cell systems. Quantitative experimental assays are used to measure cell functions, receptor/ligand interaction parameters, and signaling network dynamics. Problems are primarily motivated by health care technologies of interest to pharmaceutical and biotechnological companies, and emphasize multi-disciplinary collaborative interactions, including colleagues in both academia and industry.
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-	~~<div style="padding: 5px; color: #ffffff; background-color: #9966FF; width: 750px"></div>~~
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-	~~<div style="padding: .4em .9em .9em">~~
-	~~<font face="courier new">~~
-	'''Molecular cell bioengineering''' is the application of engineering approaches to develop quantitative understanding of cell function in terms of fundamental molecular properties, and to apply this understanding for improved design of molecular- and cell-based technologies. Our research group focuses on elucidating important aspects of receptor-mediated regulation of mammalian blood and tissue cell behavioral functions such as proliferation, adhesion, migration, differentiation, and death. A central paradigm of our work is development and testing of computational models -- based on principles from engineering analysis and synthesis -- for receptor regulation of cell function by exploiting techniques of molecular biology to alter parameters characterizing receptor or ligand properties in well-characterized cell systems. Quantitative experimental assays are used to measure cell functions, receptor/ligand interaction parameters, and signaling network dynamics. Problems are primarily motivated by health care technologies of interest to pharmaceutical and biotechnological companies, and emphasize multi-disciplinary collaborative interactions, including colleagues in both academia and industry.
-	~~</font>~~
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-	~~</div>~~
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	<div style="padding: 5px; color: #ffffff; background-color: #9966FF; width: 750px"></div>		<div style="padding: 5px; color: #ffffff; background-color: #9966FF; width: 750px"></div>

Skosuri at 20:29, 18 September 2005

Skosuri — Sun, 18 Sep 2005 20:29:01 GMT

←Older revision		Revision as of 20:29, 18 September 2005
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	<font face="trebuchet ms" style="color:#3333CC" size="6">		<font face="trebuchet ms" style="color:#3333CC" size="6">
-	Doug Lauffenburger's Research Group	+	'''Doug Lauffenburger's Research Group'''
	</font>		</font>
		+	</div>
		+	<div style="padding: 10px; color: #ffffff; background-color: #9966FF; width: 740px">
		+	<center>
		+	[[Lauffenburger Lab\| <font face="trebuchet ms" style="color:#ffffff"> '''Home''' </font>]]
		+	[[Lauffenburger:People\| <font face="trebuchet ms" style="color:#ffffff"> '''People''' </font>]]
		+	[[Lauffenburger:Research\| <font face="trebuchet ms" style="color:#ffffff"> '''Research''' </font>]]
		+	[[Synthetic Biology:Publications\| <font face="trebuchet ms" style="color:#ffffff"> '''Publications''' </font>]]
		+	[[Synthetic Biology:Internal\| <font face="trebuchet ms" style="color:#ffffff"> '''Internal''' </font>]]
		+	</center>
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Skosuri at 19:12, 18 September 2005

Skosuri — Sun, 18 Sep 2005 19:12:11 GMT

←Older revision		Revision as of 19:12, 18 September 2005
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←Older revision		Revision as of 20:36, 18 September 2005
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	[[Lauffenburger:People\| <font face="trebuchet ms" style="color:#ffffff"> '''People''' </font>]]		[[Lauffenburger:People\| <font face="trebuchet ms" style="color:#ffffff"> '''People''' </font>]]
	[[Lauffenburger:Research\| <font face="trebuchet ms" style="color:#ffffff"> '''Research''' </font>]]		[[Lauffenburger:Research\| <font face="trebuchet ms" style="color:#ffffff"> '''Research''' </font>]]
-	[[~~Synthetic Biology~~:Publications\| <font face="trebuchet ms" style="color:#ffffff"> '''Publications''' </font>]]	+	[[Lauffenburger:Publications\| <font face="trebuchet ms" style="color:#ffffff"> '''Publications''' </font>]]
-	[[~~Synthetic Biology~~:Internal\| <font face="trebuchet ms" style="color:#ffffff"> '''Internal''' </font>]]	+	[[Lauffenburger:Links\| <font face="trebuchet ms" style="color:#ffffff"> '''Links''' </font>]]
		+	[[Lauffenburger:Internal\| <font face="trebuchet ms" style="color:#ffffff"> '''Internal''' </font>]]
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