Linda and Fori's Project: Difference between revisions

Revision as of 19:48, 5 May 2009

Mod 3 Final Project: Research Proposal
Begin to define your research proposal by making a wiki page to collect your ideas and resources (you can do this on one page with your partner or split the effort and each turn in an individual page). Keep in mind that your presentation to the class will ultimately need:
- a brief project overview
- sufficient background information for everyone to understand your proposal
- a statement of the research problem and goals
- project details and methods
- predicted outcomes if everything goes according to plan and if nothing does
- needed resources to complete the work
You can organize your wiki page along these lines or however you feel is most helpful. For now, focus on coming up with a research problem and giving a little background about it. *Print your user page(s) for next time, making sure it defines your topic, your idea and two or more references you've collected and summarized. Keep in mind that you're not committed to this idea - if you come up with something that you like better later on, that's fine.

Research Problems: On of the primary causes of wrinkles is extended chronic UV exposure, which leads to photo-aging. As photons bombard the surface of the skin, elasticity is lost and wrinkling occurs. The extracellular matrix of skin cells undergoes degradation: underlying proteins, such as collagen, and fibers, such as elastin, breakdown resulting in loss of mechanical intregrity and the formation of a wrinkle.
Research Goals: To attack the root cuase of wrinkle formation by Try to reverse or reduce the loss of skin matrix by inhibiting or reducing the levels of MMP enzymes. This may especially benefit older individuals since research indicates that MMP levels rise excessively with age. It makes a good sense to try to return MMP levels to normal youthful levels, which are sufficient to remove the damaged matrix but allow you to preserve the healthy one
Predicted outcomes:

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 ==Our Idea==
-*Research Problems:
+*Research Problems: On of the primary causes of wrinkles is extended chronic UV exposure, which leads to photo-aging. As photons bombard the surface of the skin, elasticity is lost and wrinkling occurs. The extracellular matrix of skin cells undergoes degradation: underlying proteins, such as collagen, and fibers, such as elastin, breakdown resulting in loss of mechanical intregrity and the formation of a wrinkle.
-*Research Goals:
+*Research Goals: To attack the root cuase of wrinkle formation by Try to reverse or reduce the loss of skin matrix by inhibiting or reducing the levels of MMP enzymes. This may especially benefit older individuals since research indicates that MMP levels rise excessively with age. It makes a good sense to try to return MMP levels to normal youthful levels, which are sufficient to remove the damaged matrix but allow you to preserve the healthy one
 *Predicted outcomes: