Lon Chubiz: Difference between revisions
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==Research Interests== | ==Research Interests== | ||
'''Translational regulation and control strategies.''' In all branches of life organisms have evolved highly sophisticated strategies to regulate gene expression. Although transcriptional level control has been extensively studied, translational level events are becoming more important to understand. A primary example is the observation that there is very limited correlation between mRNA abundance and protein concentration. As we try to reprogram cellular behavior with increasingly sensitive systems, this paradox will become an important phenomena to understand in order to produce optimized cellular responses. | '''Translational regulation and control strategies.''' In all branches of life organisms have evolved highly sophisticated strategies to regulate gene expression. Although transcriptional level control has been extensively studied, translational level events are becoming more important to understand. A primary example is the observation that there is very limited correlation between mRNA abundance and protein concentration. As we try to reprogram cellular behavior with increasingly sensitive systems, this paradox will become an important phenomena to understand in order to produce optimized cellular responses. | ||
'''Transcriptional Regulatory Networks and Cellular Physiology.''' | '''Transcriptional Regulatory Networks and Cellular Physiology.''' | ||
Revision as of 13:27, 6 June 2008
Bio
- Fourth year graduate student in Chris Rao's group in Chemical and Biomolecular Engineering at the University of Illinois at Urbana-Champaign.
- Undergraduate degree in Chemical Engineering from the University of Minnesota.
Graduate Activities
- Member OWW Steering Committee
- Internal Vice-President ChBE Graduate Student Advisory Council (2005-2007)
- Teaching Assisant
- Mass Transfer and Separations, Spring 2007
- Process Dynamics and Control, Fall 2006
- Unit Operations, Spring 2006
- Fluid Mechanics, Fall 2005
Research Interests
Translational regulation and control strategies. In all branches of life organisms have evolved highly sophisticated strategies to regulate gene expression. Although transcriptional level control has been extensively studied, translational level events are becoming more important to understand. A primary example is the observation that there is very limited correlation between mRNA abundance and protein concentration. As we try to reprogram cellular behavior with increasingly sensitive systems, this paradox will become an important phenomena to understand in order to produce optimized cellular responses.
Transcriptional Regulatory Networks and Cellular Physiology.
Publications
- Chubiz, L.M. and Rao, C.V., Computational design of orthogonal ribosomes, Nucleic Acids Res. (2008) PMID: 18522973
Personal Interests
- Summer: Bicycling, outdoor activities.
- Winter: Snowboarding, Bicycling (yes, I actually ride my bike year-round)
- Indoor: Reading, Movies, and general R&R
Contact
- Post : Use Rao Lab mailing address.
- Email: lchubiz2 AT uiuc DOT edu
