Mag Lab

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Exterior view of the Bioscience Building
Exterior view of the Bioscience Building

Welcome to the lab wiki of the Integrative Genomics of Ageing Group. We are a highly interdisciplinary and international team, located in the heart of Liverpool (United Kingdom) and using in silico, in vitro as well as in vivo approaches to study the biology and genetics of ageing. The group's PI is Joao Pedro de Magalhaes, hence the name Mag Lab.


About our lab


Useful Links For Prospective Students

Night time lapse of the Bioscience Building
Night time lapse of the Bioscience Building

Bioinformatics Tools

Programming Language
Programming Language



News & Literature

  1. Budovsky A, Abramovich A, Cohen R, Chalifa-Caspi V, and Fraifeld V. . pmid:17116322. PubMed HubMed [Paper7]
    Creation of a human longevity-associated Network from homologous of different species. The nodes are very interesting.

  2. Lister R, Pelizzola M, Dowen RH, Hawkins RD, Hon G, Tonti-Filippini J, Nery JR, Lee L, Ye Z, Ngo QM, Edsall L, Antosiewicz-Bourget J, Stewart R, Ruotti V, Millar AH, Thomson JA, Ren B, and Ecker JR. . pmid:19829295. PubMed HubMed [Paper6]
    First step to understand the methylation pattern of cells and how it alters in time.

    This is interesting especially for two aspects: The embryonal development and the ageing process

  3. Eisenberg T, Knauer H, Schauer A, Büttner S, Ruckenstuhl C, Carmona-Gutierrez D, Ring J, Schroeder S, Magnes C, Antonacci L, Fussi H, Deszcz L, Hartl R, Schraml E, Criollo A, Megalou E, Weiskopf D, Laun P, Heeren G, Breitenbach M, Grubeck-Loebenstein B, Herker E, Fahrenkrog B, Fröhlich KU, Sinner F, Tavernarakis N, Minois N, Kroemer G, and Madeo F. . pmid:19801973. PubMed HubMed [Paper5]
    Spermidine is a small molecule, just a polyamine with a very simple structure: C7H19N3

  4. Zid BM, Rogers AN, Katewa SD, Vargas MA, Kolipinski MC, Lu TA, Benzer S, and Kapahi P. . pmid:19804760. PubMed HubMed [Paper4]
    Translating Dietary Restriction into Long Life PaperFlick Supporting Documents

  5. Veatch JR, McMurray MA, Nelson ZW, and Gottschling DE. . pmid:19563757. PubMed HubMed [Paper3]
    Mitochondrial Links to Genomic Instability in Aging PaperFlick

  6. Brunet A. . pmid:19360073. PubMed HubMed [Paper2]
    Nice essay about connections of cancer, ageing and CR

  7. Kalaany NY and Sabatini DM. . pmid:19279572. PubMed HubMed [Paper1]
    I think xenografts are a very bad model of cancer formation [DW].

All Medline abstracts: PubMed HubMed


  1. de Magalhães JP and Church GM. . pmid:17459455. PubMed HubMed [Paper7]
  2. de Magalhães JP, Sedivy JM, Finch CE, Austad SN, and Church GM. . pmid:17595413. PubMed HubMed [Paper6]
  3. de Magalhães JP and Faragher RG. . pmid:18478536. PubMed HubMed [Paper5]
  4. de Magalhães JP, Budovsky A, Lehmann G, Costa J, Li Y, Fraifeld V, and Church GM. . pmid:18986374. PubMed HubMed [Paper4]
  5. de Magalhães JP. . pmid:19418994. PubMed HubMed [Paper3]
  6. de Magalhães JP, Curado J, and Church GM. . pmid:19189975. PubMed HubMed [Paper2]
  7. de Magalhães JP and Costa J. . pmid:19522730. PubMed HubMed [Paper1]
  8. de Magalhães JP, Costa J, and Church GM. . pmid:17339640. PubMed HubMed [Paper8]
  9. de Magalhães JP and Church GM. . pmid:16226003. PubMed HubMed [Paper9]
  10. de Magalhães JP and Church GM. . pmid:16024513. PubMed HubMed [Paper10]
  11. de Magalhães JP and Sandberg A. . pmid:15946728. PubMed HubMed [Paper11]
  12. de Magalhães JP. . pmid:15619467. PubMed HubMed [Paper12]
  13. de Magalhães JP, Costa J, and Toussaint O. . pmid:15608256. PubMed HubMed [Paper13]
  14. de Magalhães JP, Chainiaux F, de Longueville F, Mainfroid V, Migeot V, Marcq L, Remacle J, Salmon M, and Toussaint O. . pmid:15489061. PubMed HubMed [Paper14]
  15. de Magalhães JP, Cabral JA, and Magalhães D. . pmid:15466429. PubMed HubMed [Paper15]
  16. de Magalhães JP. . pmid:15383309. PubMed HubMed [Paper16]
  17. de Magalhães JP and Toussaint O. . pmid:15312299. PubMed HubMed [Paper17]
  18. de Magalhães JP and Toussaint O. . pmid:15280050. PubMed HubMed [Paper18]
  19. de Magalhães JP, Migeot V, Mainfroid V, de Longueville F, Remacle J, and Toussaint O. . pmid:15247048. PubMed HubMed [Paper19]
  20. de Magalhães JP and Toussaint O. . pmid:15177050. PubMed HubMed [Paper20]
  21. de Magalhães JP. . pmid:12766537. PubMed HubMed [Paper21]
  22. de Magalhães JP and Toussaint O. . pmid:12175477. PubMed HubMed [Paper22]
  23. de Magalhães JP, Chainiaux F, Remacle J, and Toussaint O. . pmid:12123824. PubMed HubMed [Paper23]
  24. Dumont P, Royer V, Pascal T, Dierick JF, Chainiaux F, Frippiat C, de Magalhaes JP, Eliaers F, Remacle J, and Toussaint O. . pmid:11583109. PubMed HubMed [Paper24]
  25. edited by Christine Foyer, Richard Faragher, Paul Thornalley. Redox metabolism and longevity relationships in animals and plants. New York, NY: Taylor & Francis Group, 2009. isbn:9780415419543. [Book1]
  26. isbn:9780203866740. [Book2]
All Medline abstracts: PubMed HubMed
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