Mag Lab

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Exterior view of the Bioscience Building

Welcome to the lab wiki of the Integrative Genomics of Ageing Group. We are a highly interdisciplinary and international team, located in the heart of Liverpool (United Kingdom) and using in silico, in vitro as well as in vivo approaches to study the biology and genetics of ageing. The group's PI is Joao Pedro de Magalhaes, hence the name Mag Lab.

About our lab

Scientists

• Research
• Resources
• Puplications
• People
• Vacancies
• Links
• Contact

Useful Links For Prospective Students

Night time lapse of the Bioscience Building

• Introduction to Biogerontology
• The University of Liverpool
• School of Life Sciences
• Undergraduate
• Graduate School
• Finance & Funding
• Postgraduate School
• Postgraduate Handbook

Infos for Students

[Image:ezproxy.jpg|thumb|right|EZproxy]] If you are a member of the University of Liverpool you can get off-campus access to subscription-required journals (such as Science, Nature, Cell, etc. via ezproxy.

For this purpose insert ".exproxy.liv.ac.uk." right after the top-level domain (for example: .com, .gov, .de, etc.) and login with you username and password (enable cookies in the browser to avoid repeating this).

Bioinformatics/Informatics Tools/Resources

Programming Language

• HAGR (Human Ageing Genomic Resources)
• GeneAge
• GenDR
• AnAge
• Digital Ageing Atlas
• Bio-Linux
• Firefox
• Zotero

List of Suppliers

Suppliers

• UoL software downloads
• Scientific Laboratory Supplies Ltd.
• New England Biolabs (UK) Ltd
• VWR International Greiner Bio One
• QIAGEN - Sample & Assay Technologies
• Invitrogen.com a Provider of Essential Life Science Technologies
• Sigma Aldrich Home
• Welcome to BD Biosciences Europe
• Fisher Scientific UK - Laboratory supplies and chemical manufacturing/ Sigma-Genosys: Custom Oligos
• [1]
• Research Core Facilities
• Springer Protocols
• [http://www.springerlink.com/books/ SpringerLink - Books
• Table of Contents: Current Protocols in Molecular Biology : Wiley InterScience

People

• Daniel A. Wuttke
• Joao Magalhaes
• Yang Li

Collaborations

• Dr. Brian Merry, University of Liverpool, Functional and Comparative Genomics
• Prof. Dr. Alan Morgan, University of Liverpool, School of Biomedical Sciences
• Fusheng Tang, University of Arkansas, Little Rock
• Prof. Dr. Robert J. Shmookler Reis, University of Arkansas for Medical Sciences

News & Literature

1. Budovsky A, Abramovich A, Cohen R, Chalifa-Caspi V, and Fraifeld V. . pmid:17116322. PubMed HubMed [Paper7]

   Creation of a human longevity-associated Network from homologous of different species. The nodes are very interesting.

2. Lister R, Pelizzola M, Dowen RH, Hawkins RD, Hon G, Tonti-Filippini J, Nery JR, Lee L, Ye Z, Ngo QM, Edsall L, Antosiewicz-Bourget J, Stewart R, Ruotti V, Millar AH, Thomson JA, Ren B, and Ecker JR. . pmid:19829295. PubMed HubMed [Paper6]

   First step to understand the methylation pattern of cells and how it alters in time. This is interesting especially for two aspects: The embryonal development and the ageing process

3. Eisenberg T, Knauer H, Schauer A, Büttner S, Ruckenstuhl C, Carmona-Gutierrez D, Ring J, Schroeder S, Magnes C, Antonacci L, Fussi H, Deszcz L, Hartl R, Schraml E, Criollo A, Megalou E, Weiskopf D, Laun P, Heeren G, Breitenbach M, Grubeck-Loebenstein B, Herker E, Fahrenkrog B, Fröhlich KU, Sinner F, Tavernarakis N, Minois N, Kroemer G, and Madeo F. . pmid:19801973. PubMed HubMed [Paper5]

   Spermidine is a small molecule, just a polyamine with a very simple structure: C7H19N3

4. Zid BM, Rogers AN, Katewa SD, Vargas MA, Kolipinski MC, Lu TA, Benzer S, and Kapahi P. . pmid:19804760. PubMed HubMed [Paper4]

   Translating Dietary Restriction into Long Life PaperFlick Supporting Documents

5. Veatch JR, McMurray MA, Nelson ZW, and Gottschling DE. . pmid:19563757. PubMed HubMed [Paper3]

   Mitochondrial Links to Genomic Instability in Aging PaperFlick

6. Brunet A. . pmid:19360073. PubMed HubMed [Paper2]

   Nice essay about connections of cancer, ageing and CR

7. Kalaany NY and Sabatini DM. . pmid:19279572. PubMed HubMed [Paper1]

   I think xenografts are a very bad model of cancer formation [DW].

• Nature Web Focus on Ageing
• Nature Podcast on Ageing
• NPG library on Ageing

Publications

1. de Magalhães JP, Wuttke D, Wood SH, Plank M, and Vora C. . pmid:22090473. PubMed HubMed [Paper7]
2. de Magalhães JP and Matsuda A. . pmid:22188222. PubMed HubMed [Paper6]
3. Li Y and de Magalhães JP. . pmid:22205409. PubMed HubMed [Paper5]
4. Plank M, Wuttke D, van Dam S, Clarke SA, and de Magalhães JP. . pmid:22327899. PubMed HubMed [Paper4]
5. Wood SH, Craig T, Li Y, Merry B, and de Magalhães JP. . pmid:22555619. PubMed HubMed [Paper3]
6. Wuttke D and de Magalhães JP. . pmid:22722495. PubMed HubMed [Paper2]
7. Aledo JC, Valverde H, and de Magalhães JP. . pmid:22752047. PubMed HubMed [Paper1]
8. Yu C, Li Y, Holmes A, Szafranski K, Faulkes CG, Coen CW, Buffenstein R, Platzer M, de Magalhães JP, and Church GM. . pmid:22073188. PubMed HubMed [Paper8]
9. Silva AS, Wood SH, van Dam S, Berres S, McArdle A, and de Magalhães JP. . pmid:21994229. PubMed HubMed [Paper9]
10. Freitas AA and de Magalhães JP. . pmid:21600302. PubMed HubMed [Paper10]
11. de Magalhães JP. . pmid:21512206. PubMed HubMed [Paper11]
12. Freitas AA, Vasieva O, and de Magalhães JP. . pmid:21226956. PubMed HubMed [Paper12]
13. Fuellen G, Adjaye J, de Grey A, Lepperdinger G, de Magalhães JP, Sühnel J, and Wipat A. . pmid:21204651. PubMed HubMed [Paper13]
14. de Magalhães JP. . pmid:21182853. PubMed HubMed [Paper14]
15. Aledo JC, Li Y, de Magalhães JP, Ruíz-Camacho M, and Pérez-Claros JA. . pmid:21108730. PubMed HubMed [Paper15]
16. Nicholas A, de Magalhaes JP, Kraytsberg Y, Richfield EK, Levanon EY, and Khrapko K. . pmid:20538013. PubMed HubMed [Paper16]
17. Finch CE, Morgan TE, Longo VD, and de Magalhaes JP. . pmid:20415721. PubMed HubMed [Paper17]
18. Cevenini E, Bellavista E, Tieri P, Castellani G, Lescai F, Francesconi M, Mishto M, Santoro A, Valensin S, Salvioli S, Capri M, Zaikin A, Monti D, de Magalhães JP, and Franceschi C. . pmid:20388091. PubMed HubMed [Paper18]
19. de Magalhães JP, Finch CE, and Janssens G. . pmid:19900591. PubMed HubMed [Paper19]
20. de Magalhães JP and Costa J. . pmid:19522730. PubMed HubMed [Paper20]
21. de Magalhães JP. . pmid:19418994. PubMed HubMed [Paper21]
22. Maldonado J, Pereira T, and Estudo AMPA. . pmid:19388489. PubMed HubMed [Paper22]
23. de Magalhães JP, Curado J, and Church GM. . pmid:19189975. PubMed HubMed [Paper23]
24. de Magalhães JP, Budovsky A, Lehmann G, Costa J, Li Y, Fraifeld V, and Church GM. . pmid:18986374. PubMed HubMed [Paper24]
25. de Magalhães JP and Faragher RG. . pmid:18478536. PubMed HubMed [Paper25]
26. de Magalhães JP, Sedivy JM, Finch CE, Austad SN, and Church GM. . pmid:17595413. PubMed HubMed [Paper26]
27. de Magalhães JP and Church GM. . pmid:17459455. PubMed HubMed [Paper27]
28. de Magalhães JP, Costa J, and Church GM. . pmid:17339640. PubMed HubMed [Paper28]
29. de Magalhães JP and Church GM. . pmid:16226003. PubMed HubMed [Paper29]
30. de Magalhães JP. . pmid:16132471. PubMed HubMed [Paper30]
31. de Magalhães JP and Church GM. . pmid:16024513. PubMed HubMed [Paper31]
32. de Magalhães JP and Sandberg A. . pmid:15946728. PubMed HubMed [Paper32]
33. de Magalhães JP. . pmid:15619467. PubMed HubMed [Paper33]
34. de Magalhães JP, Costa J, and Toussaint O. . pmid:15608256. PubMed HubMed [Paper34]
35. de Magalhães JP, Chainiaux F, de Longueville F, Mainfroid V, Migeot V, Marcq L, Remacle J, Salmon M, and Toussaint O. . pmid:15489061. PubMed HubMed [Paper35]
36. de Magalhães JP, Cabral JA, and Magalhães D. . pmid:15466429. PubMed HubMed [Paper36]
37. de Magalhães JP. . pmid:15383309. PubMed HubMed [Paper37]
38. de Magalhães JP and Toussaint O. . pmid:15312299. PubMed HubMed [Paper38]
39. de Magalhães JP and Toussaint O. . pmid:15280050. PubMed HubMed [Paper39]
40. de Magalhães JP, Migeot V, Mainfroid V, de Longueville F, Remacle J, and Toussaint O. . pmid:15247048. PubMed HubMed [Paper40]
41. de Magalhães JP and Toussaint O. . pmid:15177050. PubMed HubMed [Paper41]
42. de Magalhães JP. . pmid:12766537. PubMed HubMed [Paper42]
43. de Magalhães JP and Toussaint O. . pmid:12175477. PubMed HubMed [Paper43]
44. de Magalhães JP, Chainiaux F, Remacle J, and Toussaint O. . pmid:12123824. PubMed HubMed [Paper44]
45. Dumont P, Royer V, Pascal T, Dierick JF, Chainiaux F, Frippiat C, de Magalhaes JP, Eliaers F, Remacle J, and Toussaint O. . pmid:11583109. PubMed HubMed [Paper45]
46. edited by Christine Foyer, Richard Faragher, Paul Thornalley. Redox metabolism and longevity relationships in animals and plants. New York, NY: Taylor & Francis Group, 2009. isbn:9780415419543. [Book1]
47. isbn:9780203866740. [Book2]