Malaria: Difference between revisions
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== OpenWetWare Projects on Malaria == | |||
A list of OpenWetWare projects on Malaria: | |||
*[[Open_Source_Drug_Discovery_-_Malaria|Open Source Drug Discovery - Malaria]] | |||
*[[Crisanti:Projects|Crisanti Group]] | |||
== Live replicating adenovirus malaria vaccine == | == Live replicating adenovirus malaria vaccine == | ||
== Plasmids == | == Plasmids == | ||
*Progenitor - pTG3602 - whole Ad5 genome with pPolyII linking ITRs. Cut with PacI to liberate infectious Ad5 DNA | *Progenitor - [[pTG3602]] - whole Ad5 genome with pPolyII linking ITRs. Cut with PacI to liberate infectious Ad5 DNA | ||
**pCP08 - Ad5 with NdeI site in fiber removed and lacZ from pUC19 stuck into NdeI site in hexon - hexon recombination plasmid | **[[pCP08]] - Ad5 with NdeI site in fiber removed and lacZ from pUC19 stuck into NdeI site in hexon - hexon recombination plasmid | ||
** | **[[pCP05]] - Ad5 with hexon deletion (15671bp-25290bp) - fiber recombination plasmid | ||
** | **[[pCP03]] - Ad5 with NdeI site in fiber removed - hexon recombination plasmid | ||
all plasmids are AmpR | all plasmids are AmpR | ||
== Viruses == | |||
*Ad5 full genome capsid display mutants | |||
**CS (circumsporozoite antigent) mutants | |||
***Gk2 - HVR1 (NANP)5 subsitution | |||
***GKIII-2 - HVR5 T* insertion between hexon AAs 272 and 273 | |||
*Ad5 late gene expression mutants | |||
**LSA3 (liver stage antigen 3) | |||
***FFH3 - hexon splice aceptor | |||
Latest revision as of 16:46, 1 February 2012
OpenWetWare Projects on Malaria
A list of OpenWetWare projects on Malaria:
Live replicating adenovirus malaria vaccine
Plasmids
- Progenitor - pTG3602 - whole Ad5 genome with pPolyII linking ITRs. Cut with PacI to liberate infectious Ad5 DNA
all plasmids are AmpR
Viruses
- Ad5 full genome capsid display mutants
- CS (circumsporozoite antigent) mutants
- Gk2 - HVR1 (NANP)5 subsitution
- GKIII-2 - HVR5 T* insertion between hexon AAs 272 and 273
- CS (circumsporozoite antigent) mutants
- Ad5 late gene expression mutants
- LSA3 (liver stage antigen 3)
- FFH3 - hexon splice aceptor
- LSA3 (liver stage antigen 3)
