Malaria
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| + | == OpenWetWare Projects on Malaria == | ||
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| + | A list of OpenWetWare projects on Malaria: | ||
| + | *[[Open_Source_Drug_Discovery_-_Malaria|Open Source Drug Discovery - Malaria]] | ||
| + | *[[Crisanti:Projects|Crisanti Group]] | ||
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== Live replicating adenovirus malaria vaccine == | == Live replicating adenovirus malaria vaccine == | ||
== Plasmids == | == Plasmids == | ||
| - | *Progenitor - pTG3602 - whole Ad5 genome with pPolyII linking ITRs. Cut with PacI to liberate infectious Ad5 DNA | + | *Progenitor - [[pTG3602]] - whole Ad5 genome with pPolyII linking ITRs. Cut with PacI to liberate infectious Ad5 DNA |
| - | **pCP08 - Ad5 with NdeI site in fiber removed and lacZ from pUC19 stuck into NdeI site in hexon - hexon recombination plasmid [[ | + | **[[pCP08]] - Ad5 with NdeI site in fiber removed and lacZ from pUC19 stuck into NdeI site in hexon - hexon recombination plasmid |
| - | **pCP03 - Ad5 with NdeI site in fiber removed - hexon recombination plasmid | + | **[[pCP05]] - Ad5 with hexon deletion (15671bp-25290bp) - fiber recombination plasmid |
| - | + | **[[pCP03]] - Ad5 with NdeI site in fiber removed - hexon recombination plasmid | |
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all plasmids are AmpR | all plasmids are AmpR | ||
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| + | == Viruses == | ||
| + | *Ad5 full genome capsid display mutants | ||
| + | **CS (circumsporozoite antigent) mutants | ||
| + | ***Gk2 - HVR1 (NANP)5 subsitution | ||
| + | ***GKIII-2 - HVR5 T* insertion between hexon AAs 272 and 273 | ||
| + | *Ad5 late gene expression mutants | ||
| + | **LSA3 (liver stage antigen 3) | ||
| + | ***FFH3 - hexon splice aceptor | ||
Current revision
Contents |
OpenWetWare Projects on Malaria
A list of OpenWetWare projects on Malaria:
Live replicating adenovirus malaria vaccine
Plasmids
- Progenitor - pTG3602 - whole Ad5 genome with pPolyII linking ITRs. Cut with PacI to liberate infectious Ad5 DNA
all plasmids are AmpR
Viruses
- Ad5 full genome capsid display mutants
- CS (circumsporozoite antigent) mutants
- Gk2 - HVR1 (NANP)5 subsitution
- GKIII-2 - HVR5 T* insertion between hexon AAs 272 and 273
- CS (circumsporozoite antigent) mutants
- Ad5 late gene expression mutants
- LSA3 (liver stage antigen 3)
- FFH3 - hexon splice aceptor
- LSA3 (liver stage antigen 3)
