Matt Gethers

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I'm currently a sophomore in course 20. When I'm behaving myself, I'm allowed to work in the Endy Lab at MIT. I have links to my UROP projects and 20.109 work directly below.


UROP Projects

Translation Demand

Mitochondrial Engineering

20.109 Work

20.310 Project

  1. Galkin O, Pan W, Filobelo L, Hirsch RE, Nagel RL, and Vekilov PG. . pmid:17449671. PubMed HubMed [Galkin]
  2. Carragher B, Bluemke DA, Gabriel B, Potel MJ, and Josephs R. . pmid:3351926. PubMed HubMed [Carragher]
  3. Bluemke DA, Carragher B, Potel MJ, and Josephs R. . pmid:3351927. PubMed HubMed [Carragher2]
  4. Carragher B, Bluemke DA, Becker M, McDade WA, Potel MJ, and Josephs R. . pmid:3351930. PubMed HubMed [Carragher3]
  5. Jones CW, Wang JC, Ferrone FA, Briehl RW, and Turner MS. . pmid:12638863. PubMed HubMed [Turner]
  6. Wang JC, Turner MS, Agarwal G, Kwong S, Josephs R, Ferrone FA, and Briehl RW. . pmid:11812133. PubMed HubMed [Wang]
All Medline abstracts: PubMed HubMed

Treatments exist for preventive and palliative treatment of sickle cell episodes, but no treatment has yet been developed to mitigate the effects of an attack once it has started. We need a way of dealing with Hbs fibers once they have polymerized. We feel we can develop a treatment for an ongoing attack by addressing the biomechanical basis of the pathology.

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