Matt Gethers/CRI, Thailand: Difference between revisions
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==Project Ideas== | ==Project Ideas== | ||
*The Fuangthong lab has done some work characterizing transcriptional regulators (I think) that are responsive to iron. It would be interesting to see if you could swap sensitivity/activator specificities (i.e. respond to hyperoxide rather than iron, but activate the same genes as Iron). This would be a considerably involved project, I think. | *The Fuangthong lab has done some work characterizing transcriptional regulators (I think) that are responsive to iron. It would be interesting to see if you could swap sensitivity/activator specificities (i.e. respond to hyperoxide rather than iron, but activate the same genes as Iron). This would be a considerably involved project, I think, but it would certainly be interesting scientificallly and it would generate some parts to add to the registry. | ||
===References=== | ===References=== | ||
Revision as of 10:21, 20 May 2008
CRI Thailand
Project Ideas
- The Fuangthong lab has done some work characterizing transcriptional regulators (I think) that are responsive to iron. It would be interesting to see if you could swap sensitivity/activator specificities (i.e. respond to hyperoxide rather than iron, but activate the same genes as Iron). This would be a considerably involved project, I think, but it would certainly be interesting scientificallly and it would generate some parts to add to the registry.
References
- Fuangthong M, Sallabhan R, Atichartpongkul S, Rangkadilok N, Sriprang R, Satayavivad J, and Mongkolsuk S. The omlA gene is involved in multidrug resistance and its expression is inhibited by coumarins in Xanthomonas campestris pv. phaseoli. Arch Microbiol. 2008 Mar;189(3):211-8. DOI:10.1007/s00203-007-0310-1 |
