Matthew R Allegretti Week 9

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Week 9 Assignment

Purpose

Methods and Results

Data and Files

Conclusion

Defining Your HIV Structure Research Project

  1. What is your question?
    • What amino acid type changes most effected the success of viral membrane fusion.
  2. Make a prediction about the answer to your question before you begin your analysis.
    • Changes from hydrophobic to charged hydrophilic will have the greatest effect on fusion.
  3. Which subjects, visits, and clones will you use to answer your question?
    • 4, 11, 9, 14. These four subjects have identical dS/dN ratios but are in different progressor groups. Sequences will be taken from visits 1 and 4, as subjects 2 and 11 only have 4 visits total.

References

Acknowledgements

Useful links

Course Home Page