Melissa Kemp: Difference between revisions
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'''Melissa Kemp''' (BE postdoctoral), in collaboration | '''Melissa Kemp''' (BE postdoctoral), in collaboration with Lucia Wille, John Burke, Christina Lewis | ||
Investigation of the signaling dynamics and cytokine responses resulting from stimulation of the T cell receptor via ligands of varying avidity. Using a systems approach, we have generated a large dataset characterizing the multivariate relationships between ligand avidity, signaling dynamics and IL-2 production in a murine T cell hybridoma line. Partial least squares regression analysis leads to a predictive model of IL-2 production in our system. | |||
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Revision as of 10:00, 6 December 2005
 Melissa Kemp (BE postdoctoral), in collaboration with Lucia Wille, John Burke, Christina Lewis Investigation of the signaling dynamics and cytokine responses resulting from stimulation of the T cell receptor via ligands of varying avidity. Using a systems approach, we have generated a large dataset characterizing the multivariate relationships between ligand avidity, signaling dynamics and IL-2 production in a murine T cell hybridoma line. Partial least squares regression analysis leads to a predictive model of IL-2 production in our system. |
